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Tumor Suppressor Candidate 2 (TUSC2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145963

Description: TUSC2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 133 amino acids (1-110) and having a molecular mass of 14.5 kDa.TUSC2 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tumor Suppressor Candidate 2 (TUSC2), Recombinant Protein
Full Product Name
Recombinant Human Tumor Suppressor Candidate 2
Product Gene Name
Product Synonym Names
TUSC2 Human; Tumor Suppressor Candidate 2 Human Recombinant; 800x600 800x600 Tumor suppressor candidate 2; C3orf11; FUS1; PAP; PDAP2; TUSC2; Fusion 1 protein; Fus-1 protein; PDGFA-associated protein 2; LGCC
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMGA SGSK ARGLWPFASA AGGGGSEAAG AEQALVRPRG RAVPPFVFTR RGSMFYDEDG DLAHEFYEET IVTKNGQKRA KLRRVHKNLI PQGIVKLDHP RIHVDFPVIL YEV
Host
E Coli
Form/Format
The TUSC2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Molecular Weight
12,074 Da
OMIM
607052
3D Structure
ModBase 3D Structure for O75896

Other Notes

Small volumes of TUSC2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TUSC2 purchase

MBS145963 is a recombinant protein targeting TUSC2. Also known as Recombinant Human Tumor Suppressor Candidate 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TUSC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tumor suppressor candidate 2
NCBI Official Synonym Full Names
tumor suppressor candidate 2
NCBI Official Symbol
TUSC2
NCBI Official Synonym Symbols
PAP; FUS1; PDAP2; C3orf11
UniProt Protein Name
Tumor suppressor candidate 2
UniProt Synonym Protein Names
Fusion 1 protein; Fus-1 protein; PDGFA-associated protein 2
UniProt Gene Name
TUSC2
UniProt Synonym Gene Names
C3orf11; FUS1; LGCC; PDAP2; Fus-1 protein
UniProt Entry Name
TUSC2_HUMAN
NCBI Protein Information
tumor suppressor candidate 2; PDGFA associated protein 2; PDGFA-associated protein 2; fus-1 protein; fusion 1 protein

NCBI Summary for TUSC2

This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008]

UniProt Comments for TUSC2

TUSC2: May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. Belongs to the TUSC2 family.

Protein type: Tumor suppressor

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: mitochondrion

Biological Process: interleukin-15 production; cell proliferation; negative regulation of interleukin-17 production; cell-cell signaling; regulation of mitochondrial membrane potential; natural killer cell differentiation; response to defense-related host reactive oxygen species production; cell maturation; cell cycle; inflammatory response; positive regulation of interleukin-10 production; phagocytosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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