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Prolactin Regulatory Element-Binding Protein (PREB) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1459818

This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients… More details

$1585 / 0.5 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Prolactin regulatory element-binding protein (Preb), Recombinant Protein
Full Product Name
Recombinant Mouse Prolactin regulatory element-binding protein (Preb), partial
Product Gene Name
Preb recombinant protein
Product Synonym Gene Name
Preb
Sequence
MGRRRGVELY RAPFPLYALR IDPKTGLLIA AGGGGAAKTG IKNGVHFLQL ELINGCLSAS LLHSHDTETR ATMNLALAGD ILAAGQDAQC QLLRFQVHQQ KGSKAEKSGS KEQGPRQRKG APPAEKKSGA QVHPEGVELK VKNLEAVQTD FSNEPLQKVV CFNHDNTLLA TGGTDGHVRV WKVPSLEKVL EFKAHEGEIG DLTLGPDGKL VTVGWDFKAS VWQKDQLVTQ LQWQENGPAS SNTPYRYQAC RFGQVPDQLG GLRLFTVQIP HKRLRQPPPC YLTAWDSSTF LPLRTRSCGH EVISCLSVSD SGTFLGLGTV TGSVAIYIAF SLQRLYYVKE AHGIVVTDVT FLPEKGCGPK LLGPHETALF SVAVDSRCQL HLLPSRRS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
45,437 Da
Sequence Positions
1-388
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9WUQ2
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Preb recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Preb purchase

MBS1459818 is a recombinant protein targeting Preb. Also known as Recombinant Mouse Prolactin regulatory element-binding protein (Preb), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Preb. It may not necessarily be applicable to this product.

NCBI GI #
158749640
NCBI GeneID
50907
NCBI Accession #
NP_057912.2
UniProt Primary Accession #
Q9WUQ2
UniProt Secondary Accession #
Q9QZ99
UniProt Related Accession #
Q9WUQ2
GenBank Nucleotide #
NM_016703.3
NCBI Official Full Name
prolactin regulatory element-binding protein isoform 1
NCBI Official Synonym Full Names
prolactin regulatory element binding
NCBI Official Symbol
Preb
NCBI Official Synonym Symbols
C85705
UniProt Protein Name
Prolactin regulatory element-binding protein
UniProt Synonym Protein Names
Mammalian guanine nucleotide exchange factor mSec12
Protein Family
Prolactin regulatory element-binding protein
UniProt Gene Name
Preb
UniProt Synonym Gene Names
Sec12
NCBI Protein Information
prolactin regulatory element-binding protein

UniProt Comments for Preb

Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitement of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.

Research Articles on Preb

1. PREB may contribute to the regulation of ApN gene transcription, in response to cAMP activation in adipocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Preb recombinant protein

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 COPII (Coat Protein 2) Mediated Vesicle Transport Pathway antibodies  COPII (Coat Protein 2) Mediated Vesicle Transport Pathway Diagram
 ER To Golgi Transport Pathway antibodies  ER To Golgi Transport Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Transport To The Golgi And Subsequent Modification Pathway antibodies  Transport To The Golgi And Subsequent Modification Pathway Diagram

Diseases associated with Preb recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >58 publications with Preb and Neoplasms
 Lymphoma Antibodies  >46 publications with Preb and Lymphoma
 Drug Toxicity Antibodies  >7 publications with Preb and Drug Toxicity
 Cell Transformation, Neoplastic Antibodies  >7 publications with Preb and Cell Transformation, Neoplastic
 Necrosis Antibodies  >6 publications with Preb and Necrosis
 Prenatal Exposure Delayed Effects Antibodies  >4 publications with Preb and Prenatal Exposure Delayed Effects
 Pregnancy Complications Antibodies  >4 publications with Preb and Pregnancy Complications
 Disease Models, Animal Antibodies  >3 publications with Preb and Disease Models, Animal
 Anemia Antibodies  >2 publications with Preb and Anemia
 Prostatic Diseases Antibodies  >1 publications with Preb and Prostatic Diseases

Organs/Tissues associated with Preb recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >110 publications with Preb and Blood
 Bone Antibodies  >57 publications with Preb and Bone
 Bone Marrow Antibodies  >54 publications with Preb and Bone Marrow
 Spleen Antibodies  >18 publications with Preb and Spleen
 Liver Antibodies  >13 publications with Preb and Liver
 Brain Antibodies  >12 publications with Preb and Brain
 Embryonic Tissue Antibodies  >7 publications with Preb and Embryonic Tissue
 Pituitary Gland Antibodies  >6 publications with Preb and Pituitary Gland
 Lung Antibodies  >6 publications with Preb and Lung
 Pancreas Antibodies  >3 publications with Preb and Pancreas
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