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Cathelicidin Antimicrobial (CAMP) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146033

Description: CAMP Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 163 amino acids (34-173 a.a.) and having a molecular mass of 18.4kDa.CAMP is fused to a 23 amino acid His-tag at N-terminus.Introduction: CAMP… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cathelicidin Antimicrobial (CAMP), Recombinant Protein
Full Product Name
Recombinant Human Cathelicidin Antimicrobial Peptide
Product Gene Name
Product Synonym Names
CAMP Human; Cathelicidin Antimicrobial Peptide Human Recombinant; CAP-18; CAP18; CRAMP; FALL-39; FALL39; HSD26; LL37; 18 kDa cationic antimicrobial protein; FALL-39 peptide antibiotic; Cathelicidin antimicrobial peptide
Sequence
MGSSHHH HHH SSGLVPRGSH MGSQVL SYKE AVLRAIDGIN QRSSDANLYR LLDLDPRPTM DGDPDTPKPV SFTVKETVCP RTTQQSPEDC DFKKDGLVKR CMGTVTLNQA RGSFDISCDK DNKRFALLGD FFRKSKEKIG KEFKRIVQRI KDFLRNLVPR TES
Host
E Coli
Form/Format
CAMP protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used withing 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1 HSA or BSA).
Avoid multiple freeze-thaw cycles.
Molecular Weight
19,301 Da
OMIM
600474
3D Structure
ModBase 3D Structure for P49913

Other Notes

Small volumes of CAMP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CAMP purchase

MBS146033 is a recombinant protein targeting CAMP. Also known as Recombinant Human Cathelicidin Antimicrobial Peptide. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CAMP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cathelicidin antimicrobial peptide preproprotein
NCBI Official Synonym Full Names
cathelicidin antimicrobial peptide
NCBI Official Symbol
CAMP
NCBI Official Synonym Symbols
LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39
UniProt Protein Name
Cathelicidin antimicrobial peptide
UniProt Synonym Protein Names
18 kDa cationic antimicrobial protein; CAP-18; hCAP-18
UniProt Gene Name
CAMP
UniProt Synonym Gene Names
CAP18; FALL39; CAP-18; hCAP-18
UniProt Entry Name
CAMP_HUMAN
NCBI Protein Information
cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein

NCBI Summary for CAMP

This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]
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UniProt Comments for CAMP

CAMP: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Belongs to the cathelicidin family.

Protein type: Cell cycle regulation; Secreted, signal peptide; Vesicle; Secreted

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: extracellular space; specific granule; cell projection; cell wall; cytosol

Molecular Function: protein binding

Biological Process: interaction with host; positive regulation of angiogenesis; defense response to Gram-positive bacterium; innate immune response in mucosa; killing by host of symbiont cells; defense response to bacterium; positive regulation of cell proliferation; antibacterial humoral response; positive regulation of protein amino acid phosphorylation; defense response to Gram-negative bacterium
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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