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Mitochondrial RRNA Methyltransferase 1 (MRM1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146035

Description: MRM1 Human Recombinant produced in E Coli is a single polypeptide chain containing 356 amino acids (21-353) and having a molecular mass of 38.8kDa. MRM1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mitochondrial RRNA Methyltransferase 1 (MRM1), Recombinant Protein
Full Product Name
Recombinant Human Mitochondrial RRNA Methyltransferase 1
Product Gene Name
Product Synonym Names
MRM1 Human; Mitochondrial RRNA Methyltransferase 1 Human Recombinant; Mitochondrial rRNA methyltransferase 1 homolog; rRNA methyltransferase 1; mitochondrial; Mitochondrial large ribosomal RNA ribose methylase; MRM1
Sequence
MGSSHHH HHH SSGLVPRGSH MGSSHA ARHG ERPGGEELSR LLLDDLVPTS RLELLFGMTP CLLALQAARR SVARLLLQAG KAGLQGKRAE LLRMAEARDI PVLRPRRQKL DTMCRYQVHQ GVCMEVSPLR PRPWREAGEA SPGDDPQQLW LVLDGIQDPR NFGAVLRSAH FLGVDKVITS RRNSCPLTPV VSKSSAGAME VMDVFSTDDL TGFLQTKAQQ GWLVAGTVGC PSTEDPQSSE IPIMSCLEFL WERPTLLVLG NEGSGLSQEV QASCQLLLTI LPRRQLPPGL ESLNVSVAAG ILLHSICSQR KGFPTEGERR QLLQDPQEPS ARSEGLSMAQ HPGLSSGPEK ERQNEG
Host
E Coli
Form/Format
The MRM1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 30% glycerol, 1mM DTT and 0.1mM PMSF.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Molecular Weight
16,770 Da
3D Structure
ModBase 3D Structure for Q6IN84

Other Notes

Small volumes of MRM1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MRM1 purchase

MBS146035 is a recombinant protein targeting MRM1. Also known as Recombinant Human Mitochondrial RRNA Methyltransferase 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MRM1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rRNA methyltransferase 1, mitochondrial
NCBI Official Synonym Full Names
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NCBI Official Symbol
MRM1
UniProt Protein Name
rRNA methyltransferase 1, mitochondrial
UniProt Synonym Protein Names
16S rRNA (guanosine(1145)-2'-O)-methyltransferase; 16S rRNA [Gm1145] 2'-O-methyltransferase
UniProt Gene Name
MRM1
UniProt Entry Name
MRM1_HUMAN
NCBI Protein Information
rRNA methyltransferase 1, mitochondrial; 16S rRNA (guanosine(1145)-2'-O)-methyltransferase; 16S rRNA [Gm1145] 2'-O-methyltransferase; mitochondrial large ribosomal RNA ribose methylase

UniProt Comments for MRM1

MRM1: Probably methylates the ribose of guanosine G-2270 in the peptidyl transferase center of the mitochondrial large ribosomal RNA (21S). Belongs to the RNA methyltransferase TrmH family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.1.1.-; Methyltransferase

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: mitochondrion

Molecular Function: RNA methyltransferase activity

Biological Process: RNA processing; RNA methylation; rRNA processing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with MRM1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with MRM1 and Muscle
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