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MAP3K12 Binding Inhibitory Protein 1 (MBIP) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146045

Description: MBIP Human Recombinant produced in E Coli is a single polypeptide chain containing 367 amino acids (1-344) and having a molecular mass of 41.7kDa. MBIP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MAP3K12 Binding Inhibitory Protein 1 (MBIP), Recombinant Protein
Full Product Name
Recombinant Human MAP3K12 Binding Inhibitory Protein 1
Product Gene Name
Product Synonym Names
MBIP Human; MAP3K12 Binding Inhibitory Protein 1 Human Recombinant; MAP3K12 binding inhibitory protein 1; MAPK upstream kinase-binding inhibitory protein; MUK-binding inhibitory protein; MBIP
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMAA ATEL NRPSSGDRNL ERRCRPNLSR EVLYEIFRSL HTLVGQLDLR DDVVKITIDW NKLQSLSAFQ PALLFSALEQ HILYLQPFLA KLQSPIKEEN TTAVEEIGRT EMGNKNEVND KFSIGDLQEE EKHKESDLRD VKKTQIHFDP EVVQIKAGKA EIDRRISAFI ERKQAEINEN NVREFCNVID CNQENSCART DAIFTPYPGF KSHVKVSRVV NTYGPQTRPE GIPGSGHKPN SMLRDCGNQA VEERLQNIEA HLRLQTGGPV PRDIYQRIKK LEDKILELEG ISPEYFQSVS FSGKRRKVQP PQQNYSLAEL DEKISALKQA LLRKSREAES MATHHLP
Host
E Coli
Form/Format
The MBIP solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
Sterile Filtered clear solution.
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Molecular Weight
39,153 Da
OMIM
609431
3D Structure
ModBase 3D Structure for Q9NS73

Other Notes

Small volumes of MBIP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MBIP purchase

MBS146045 is a recombinant protein targeting MBIP. Also known as Recombinant Human MAP3K12 Binding Inhibitory Protein 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MBIP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
MAP3K12-binding inhibitory protein 1 isoform 2
NCBI Official Synonym Full Names
MAP3K12 binding inhibitory protein 1
NCBI Official Symbol
MBIP
UniProt Protein Name
MAP3K12-binding inhibitory protein 1
UniProt Synonym Protein Names
MAPK upstream kinase-binding inhibitory protein; MUK-binding inhibitory protein
UniProt Gene Name
MBIP
UniProt Synonym Gene Names
MUK-binding inhibitory protein
UniProt Entry Name
MBIP1_HUMAN
NCBI Protein Information
MAP3K12-binding inhibitory protein 1; MAPK upstream kinase-binding inhibitory protein; MUK-binding inhibitory protein

UniProt Comments for MBIP

MBIP: Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, regulatory subunit

Chromosomal Location of Human Ortholog: 14q13.3

Cellular Component: cytoplasm; nucleolus; nucleus

Molecular Function: identical protein binding; protein binding; protein kinase inhibitor activity

Biological Process: establishment and/or maintenance of chromatin architecture; inactivation of MAPK activity during osmolarity sensing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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