Human CD100 Recombinant Protein – Cat# MBS146111

CD100 Human Recombinant Protein

Name: CD100 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS146111
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146111

Description: CD100 Human Recombinant produced by mammalian expression system in human cells is a single polypeptide chain containing 721 amino acids (22-734). CD100 is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD100, Recombinant Protein

Full Product Name

Recombinant Human CD100

Product Gene Name

CD100 recombinant protein

Product Synonym Names

CD100 Human HEK; CD100 Human Recombinant HEK; Thesemaphorin family containing 1 Ig-like C2-type domain; 1 PSI domain and 1 Sema domai; Semaphorin-4D; A8; BB18; GR3; SEMA4D; C9orf164; CD100; SEMAJ

Sequence

MAFAPIPRIT WEHREVHLVQ FHEPDIYNYS ALLLSEDKDT LYIGAREAVF AVNALNISEK QHEVYWKVSE DKKAKCAEKG KSKQTECLNY IRVLQPLSAT SLYVCGTNAF QPACDHLNLT SFKFLGKNED GKGRCPFDPA HSYTSVMVDG ELYSGTSYNF LGSEPIISRN SSHSPLRTEY AIPWLNEPSF VFADVIRKSP DSPDGEDDRV YFFFTEVSVE YEFVFRVLIP RIARVCKGDQ GGLRTLQKKW TSFLKARLIC SRPDSGLVFN VLRDVFVLRS PGLKVPVFYA LFTPQLNNVG LSAVCAYNLS TAEEVFSHGK YMQSTTVEQS HTKWVRYNGP VPKPRPGACI DSEARAANYT SSLNLPDKTL QFVKDHPLMD DSVTPIDNRP RLIKKDVNYT QIVVDRTQAL DGTVYDVMFV STDRGALHKA ISLEHAVHII EETQLFQDFE PVQTLLLSSK KGNRFVYAGS NSGVVQAPLA FCGKHGTCED CVLARDPYCA WSPPTATCVA LHQTESPSRG LIQEMSGDAS VCPDKSKGSY RQHFFKHGGT AELKCSQKSN SEKTMYLKSS DNRVDHHHHH H.

Host

HEK293 Cells

Form/Format

CD100 was lyophilized from a 0.2 uM filtered solution of 20mM PB and 150mM NaCl, PH 7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Greater than 95% as determined by SDS-PAGE.

Molecular Weight

82,164 Da

OMIM

601866

3D Structure

ModBase 3D Structure for Q92854

Solubility

It is recommended to reconstitute the lyophilized CCD100 in 1xPBS to a concentration no less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Product Categories/Family for CD100 recombinant protein

Recombinant & Natural Proteins; CD Antigens

Other Notes

Small volumes of CD100 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD100 purchase

MBS146111 is a recombinant protein targeting CD100. Also known as Recombinant Human CD100. Host: HEK293 Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for CD100. It may not necessarily be applicable to this product.

NCBI GI #

214010220

NCBI GeneID

10507

NCBI Accession #

NP_001135759.1

UniProt Primary Accession #

Q92854

UniProt Secondary Accession #

Q7Z5S4; Q8N8B0; B2RPM6

UniProt Related Accession #

Q92854

GenBank Nucleotide #

NM_001142287.1

NCBI Official Full Name

semaphorin-4D isoform 2

NCBI Official Synonym Full Names

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

NCBI Official Symbol

SEMA4D

NCBI Official Synonym Symbols

CD100; SEMAJ; coll-4; C9orf164; M-sema-G

UniProt Protein Name

Semaphorin-4D

UniProt Synonym Protein Names

A8; BB18; GR3; CD_antigen: CD100

Protein Family

Semaphorin

UniProt Gene Name

SEMA4D

UniProt Synonym Gene Names

C9orf164; CD100; SEMAJ

UniProt Entry Name

SEM4D_HUMAN

NCBI Protein Information

semaphorin-4D; A8; BB18; GR3; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D

UniProt Comments for CD100

SEMA4D: a single-pass type I membrane protein that my play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q22.2

Cellular Component: extracellular space; integral to plasma membrane; plasma membrane

Molecular Function: protein binding; transmembrane receptor activity; receptor activity; semaphorin receptor binding; receptor binding

Biological Process: axon guidance; negative regulation of peptidyl-tyrosine phosphorylation; regulation of dendrite morphogenesis; negative regulation of cell adhesion; negative regulation of transcription from RNA polymerase II promoter; positive regulation of phosphoinositide 3-kinase cascade; regulation of cell shape; positive regulation of peptidyl-tyrosine phosphorylation; immune response; negative regulation of osteoblast differentiation; positive regulation of protein amino acid phosphorylation; cell adhesion; positive regulation of collateral sprouting; negative regulation of apoptosis; positive regulation of cell migration; regulation of cell projection organization and biogenesis

Research Articles on CD100

1. Sema4D contributes to enhanced invasion and tumor progression through increased motility of cervical cancer and VEGF-C/-D-mediated lymphangiogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CD100 recombinant protein

Reference Product	PubMed Publications
PLXNB1 recombinant protein	>68 publications with CD100 and PLXNB1
CD72 recombinant protein	>36 publications with CD100 and CD72
MET recombinant protein	>18 publications with CD100 and MET
ERBB2 recombinant protein	>7 publications with CD100 and ERBB2
PTPRC recombinant protein	>5 publications with CD100 and PTPRC
RND1 recombinant protein	>4 publications with CD100 and RND1
RRAS recombinant protein	>3 publications with CD100 and RRAS
ARHGEF12 recombinant protein	>2 publications with CD100 and ARHGEF12
ARHGEF11 recombinant protein	>2 publications with CD100 and ARHGEF11
GRLF1 recombinant protein	>1 publications with CD100 and GRLF1

Pathways associated with CD100 recombinant protein

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Other Semaphorin Interactions Pathway antibodies	Other Semaphorin Interactions Pathway Diagram
Sema4D In Semaphorin Signaling Pathway antibodies	Sema4D In Semaphorin Signaling Pathway Diagram
Sema4D Induced Cell Migration And Growth-cone Collapse Pathway antibodies	Sema4D Induced Cell Migration And Growth-cone Collapse Pathway Diagram
Sema4D Mediated Inhibition Of Cell Attachment And Migration Pathway antibodies	Sema4D Mediated Inhibition Of Cell Attachment And Migration Pathway Diagram
Semaphorin Interactions Pathway antibodies	Semaphorin Interactions Pathway Diagram

Diseases associated with CD100 recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>25 publications with CD100 and Nervous System Diseases
Brain Diseases Antibodies	>15 publications with CD100 and Brain Diseases
Neovascularization, Pathologic Antibodies	>14 publications with CD100 and Neovascularization, Pathologic
Inflammation Antibodies	>12 publications with CD100 and Inflammation
Disease Models, Animal Antibodies	>10 publications with CD100 and Disease Models, Animal
Cardiovascular Diseases Antibodies	>9 publications with CD100 and Cardiovascular Diseases
Kidney Diseases Antibodies	>4 publications with CD100 and Kidney Diseases
Necrosis Antibodies	>4 publications with CD100 and Necrosis
Lung Diseases Antibodies	>3 publications with CD100 and Lung Diseases
Atherosclerosis Antibodies	>3 publications with CD100 and Atherosclerosis

Organs/Tissues associated with CD100 recombinant protein

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>96 publications with CD100 and Nerve
Blood Antibodies	>80 publications with CD100 and Blood
Brain Antibodies	>32 publications with CD100 and Brain
Embryonic Tissue Antibodies	>17 publications with CD100 and Embryonic Tissue
Skin Antibodies	>8 publications with CD100 and Skin
Spinal Cord Antibodies	>7 publications with CD100 and Spinal Cord
Kidney Antibodies	>7 publications with CD100 and Kidney
Lymph Node Antibodies	>7 publications with CD100 and Lymph Node
Lung Antibodies	>6 publications with CD100 and Lung
Liver Antibodies	>5 publications with CD100 and Liver