Human PGLYRP1 Recombinant Protein – Cat# MBS146131

Peptidoglycan Recognition Protein 1 (PGLYRP1) Human Recombinant Protein

Name: PGLYRP1 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS146131
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146131

Description: PGLYRP1 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain (a.a 22-196) containing 185 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 20.68kDa (calculated).Introduction:… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Peptidoglycan Recognition Protein 1 (PGLYRP1), Recombinant Protein

Full Product Name

Recombinant Human Peptidoglycan Recognition Protein 1

Product Gene Name

PGLYRP1 recombinant protein

Product Synonym Names

PGLYRP1 Human; Peptidoglycan Recognition Protein 1 Human Recombinant; Peptidoglycan recognition protein 1; Peptidoglycan recognition protein short; PGRP-S; PGLYRP1; PGLYRP; PGRP; TNFSF3L; TAG7; PGRPS

Sequence

MKHHHHH HASQET EDPACCS PIVPRNEWKA LASECAQHLS LPLRYVVVSH TAGSSCNTPA SCQQQARNVQ HYHMKTLGWC DVGYNFLIGE DGLVYEGRGW NFTGAHSGHL WNPMSIGISF MGNYMDRVPT PQAIRAAQGL LACGVAQGAL RSNYVLKGHR DVQRTLSPGN QLYHLIQNWP HYRSP.

Host

E Coli

Form/Format

PGLYRP1 filtered (0.4 um) and lyophilized from 0.5mg/ml in 0.05M Acetate buffer pH-4.0.
Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Purity as determined by densitometric image analysis is greater than 90%.

Preparation and Storage

Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.

Molecular Weight

21,731 Da

OMIM

604963

3D Structure

ModBase 3D Structure for O75594

Solubility

It is recommended to add 200 ul of 0.1M Acetate buffer pH-4 to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely at 37 degree C. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10 ug/ml. In higher concentrations the solubility of this antigen is limited. PGLYRP1 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Product Categories/Family for PGLYRP1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of PGLYRP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PGLYRP1 purchase

MBS146131 is a recombinant protein targeting PGLYRP1. Also known as Recombinant Human Peptidoglycan Recognition Protein 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PGLYRP1. It may not necessarily be applicable to this product.

NCBI GI #

4827036

NCBI GeneID

8993

NCBI Accession #

NP_005082.1

UniProt Primary Accession #

O75594

UniProt Secondary Accession #

Q4VB36

UniProt Related Accession #

O75594

GenBank Nucleotide #

NM_005091.2

NCBI Official Full Name

peptidoglycan recognition protein 1

NCBI Official Synonym Full Names

peptidoglycan recognition protein 1

NCBI Official Symbol

PGLYRP1

NCBI Official Synonym Symbols

PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L

UniProt Protein Name

Peptidoglycan recognition protein 1

UniProt Synonym Protein Names

Peptidoglycan recognition protein short; PGRP-S

Protein Family

Peptidoglycan recognition protein

UniProt Gene Name

PGLYRP1

UniProt Synonym Gene Names

PGLYRP; PGRP; TNFSF3L; PGRP-S

UniProt Entry Name

PGRP1_HUMAN

NCBI Protein Information

peptidoglycan recognition protein 1; TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein)

UniProt Comments for PGLYRP1

PGLYRP1: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

Protein type: Secreted, signal peptide; Apoptosis; Secreted; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.2-q13.3

Cellular Component: extracellular region

Molecular Function: peptidoglycan receptor activity; peptidoglycan binding; zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity

Biological Process: defense response to Gram-positive bacterium; negative regulation of natural killer cell differentiation during immune response; detection of bacterium; negative regulation of interferon-gamma production; negative regulation of inflammatory response; innate immune response; immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process

Research Articles on PGLYRP1

1. shown that HspBP1 binds Tag7 in the conditioned medium of tumor CSML0 cells, thereby preventing formation of the cytotoxic Tag7-Hsp70 complex

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PGLYRP1 recombinant protein

Reference Product	PubMed Publications
HSPBP1 recombinant protein	>3 publications with PGLYRP1 and HSPBP1
S100A4 recombinant protein	>3 publications with PGLYRP1 and S100A4
NOD2 recombinant protein	>2 publications with PGLYRP1 and NOD2
NOD1 recombinant protein	>1 publications with PGLYRP1 and NOD1

Diseases associated with PGLYRP1 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>8 publications with PGLYRP1 and Inflammation
Disease Models, Animal Antibodies	>7 publications with PGLYRP1 and Disease Models, Animal
Necrosis Antibodies	>6 publications with PGLYRP1 and Necrosis
Adenocarcinoma Antibodies	>3 publications with PGLYRP1 and Adenocarcinoma
Respiratory Hypersensitivity Antibodies	>2 publications with PGLYRP1 and Respiratory Hypersensitivity
Lung Diseases Antibodies	>2 publications with PGLYRP1 and Lung Diseases
Hyperplasia Antibodies	>2 publications with PGLYRP1 and Hyperplasia
Neoplasms, Experimental Antibodies	>1 publications with PGLYRP1 and Neoplasms, Experimental
Liver Diseases Antibodies	>1 publications with PGLYRP1 and Liver Diseases
Cardiovascular Diseases Antibodies	>1 publications with PGLYRP1 and Cardiovascular Diseases

Organs/Tissues associated with PGLYRP1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>19 publications with PGLYRP1 and Blood
Bone Marrow Antibodies	>2 publications with PGLYRP1 and Bone Marrow