Human CGB Recombinant Protein – Cat# MBS146195

Chorionic Gonadotropin Beta (CGB) Human Recombinant Protein

Name: CGB Recombinant Protein; Chorionic Gonadotropin Beta; Human; MyBioSource
Brand: MyBioSource
SKU: MBS146195
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146195

Description: CGB Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 168 amino acids (21-165 a.a.) and having a molecular mass of 17.9kDa. CGB is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Chorionic Gonadotropin Beta (CGB), Recombinant Protein

Full Product Name

Recombinant Human Chorionic Gonadotropin Beta

Product Gene Name

CGB recombinant protein

Product Synonym Names

CGB Human; Chorionic Gonadotropin Beta Human Recombinant; CGB3; CGB5; CGB7; CGB8; hCGB; Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotrophin chain beta; CGB

Sequence

MGSSHHH HHH SSGLVPRGSH MGSSKE PLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQ

Host

E Coli

Form/Format

Sterile filtered colorless solution; CGB protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

Purity/Purification

Greater than 85.0% as determined by SDS-PAGE.

Preparation and Storage

Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

OMIM

118860

3D Structure

ModBase 3D Structure for P01233

Product Categories/Family for CGB recombinant protein

Hormones; Hormones; HCG

Other Notes

Small volumes of CGB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CGB purchase

MBS146195 is a recombinant protein targeting CGB. Also known as Recombinant Human Chorionic Gonadotropin Beta. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CGB. It may not necessarily be applicable to this product.

NCBI GI #

4502789

NCBI GeneID

1082

NCBI Accession #

NP_000728.1

UniProt Primary Accession #

P01233

UniProt Secondary Accession #

Q13991; Q14000; Q3KPI3; Q3SY41; Q8WTT5; Q8WXL1; Q8WXL2; Q8WXL3; Q8WXL4; A1A5E0; B9ZVP5

UniProt Related Accession #

P01233

GenBank Nucleotide #

NM_000737.3

NCBI Official Full Name

choriogonadotropin subunit beta

NCBI Official Synonym Full Names

chorionic gonadotropin, beta polypeptide

NCBI Official Symbol

CGB

NCBI Official Synonym Symbols

CGB3; CGB5; CGB7; CGB8; hCGB

UniProt Protein Name

Choriogonadotropin subunit beta

UniProt Synonym Protein Names

Chorionic gonadotrophin chain beta

Protein Family

Choriogonadotropin

UniProt Gene Name

CGB

UniProt Synonym Gene Names

CGB3; CG-beta

UniProt Entry Name

CGHB_HUMAN

NCBI Protein Information

choriogonadotropin subunit beta; CG-beta; chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit

NCBI Summary for CGB

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

UniProt Comments for CGB

CGB: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Belongs to the glycoprotein hormones subunit beta family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Inhibitor; Secreted

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: cellular protein metabolic process; cell-cell signaling; apoptosis; peptide hormone processing; female gamete generation; signal transduction

Research Articles on CGB

1. A protective effect of hCG against breast cancer may be associated with its growth inhibitory and differentiation induction function in breast cancer cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CGB recombinant protein

Products by Pathway	Pathway Diagram
Glycoprotein Hormones Pathway antibodies	Glycoprotein Hormones Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Peptide Hormone Biosynthesis Pathway antibodies	Peptide Hormone Biosynthesis Pathway Diagram
Peptide Hormone Metabolism Pathway antibodies	Peptide Hormone Metabolism Pathway Diagram

Diseases associated with CGB recombinant protein

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>20 publications with CGB and Breast Neoplasms
Cardiovascular Diseases Antibodies	>8 publications with CGB and Cardiovascular Diseases
Congenital Abnormalities Antibodies	>5 publications with CGB and Congenital Abnormalities
Pain Antibodies	>5 publications with CGB and Pain
Fibrosis Antibodies	>5 publications with CGB and Fibrosis
Inflammation Antibodies	>5 publications with CGB and Inflammation
Neoplasm Invasiveness Antibodies	>4 publications with CGB and Neoplasm Invasiveness
Hypertension Antibodies	>4 publications with CGB and Hypertension
Neoplasms, Experimental Antibodies	>4 publications with CGB and Neoplasms, Experimental
Hyperplasia Antibodies	>4 publications with CGB and Hyperplasia

Organs/Tissues associated with CGB recombinant protein

Organ/Tissue Name	Pubmed Publications
Placenta Antibodies	>25 publications with CGB and Placenta
Embryonic Tissue Antibodies	>13 publications with CGB and Embryonic Tissue
Heart Antibodies	>8 publications with CGB and Heart
Testis Antibodies	>6 publications with CGB and Testis
Skin Antibodies	>4 publications with CGB and Skin