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TEN1 Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146234

Description: TEN1 Human Recombinant produced in E Coli is a single polypeptide chain containing 146 amino acids (1-123) and having a molecular mass of 16.2kDa. TEN1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TEN1, Recombinant Protein
Full Product Name
Recombinant Human TEN1
Product Gene Name
Product Synonym Names
TEN1 Human; TEN1 Human Recombinant; TEN1 telomerase capping complex subunit homolog (S. cerevisiae); C17orf106; CST complex subunit TEN1; Protein telomeric pathways with STN1 homolog; Telomere length regulation protein TEN1 homolog; TEN1
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMML PKPG TYYLPWEVSA GQVPDGSTLR TFGRLCLYDM IQSRVTLMAQ HGSDQHQVLV CTKLVEPFHA QVGSLYIVLG ELQHQQDRGS VVKARVLTCV EGMNLPLLEQ AIREQRLYKQ ERGGSQ
Host
E Coli
Form/Format
The TEN1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered clear solution.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Molecular Weight
13,856 Da
OMIM
613130
3D Structure
ModBase 3D Structure for Q86WV5

Other Notes

Small volumes of TEN1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TEN1 purchase

MBS146234 is a recombinant protein targeting TEN1. Also known as Recombinant Human TEN1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TEN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CST complex subunit TEN1
NCBI Official Synonym Full Names
TEN1 CST complex subunit
NCBI Official Symbol
TEN1
NCBI Official Synonym Symbols
C17orf106
UniProt Protein Name
CST complex subunit TEN1
UniProt Synonym Protein Names
Protein telomeric pathways with STN1 homolog; Telomere length regulation protein TEN1 homolog
Protein Family
UniProt Gene Name
TEN1
UniProt Synonym Gene Names
C17orf106
UniProt Entry Name
TEN1L_HUMAN
NCBI Protein Information
CST complex subunit TEN1; TEN1 telomerase capping complex subunit homolog; protein telomeric pathways with STN1 homolog; telomere length regulation protein TEN1 homolog; telomeric pathways in association with Stn1, number 1

NCBI Summary for TEN1

C17ORF106, or TEN1, appears to function in a telomere-associated complex with STN1 (OBFC1; MIM 613128) and CTC1 (C17ORF68; MIM 613129) (Miyake et al., 2009 [PubMed 19854130]).[supplied by OMIM, Nov 2009]

UniProt Comments for TEN1

LOC100134934: Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites. Belongs to the TEN1 family.

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: nuclear chromosome, telomeric region; nucleus

Molecular Function: protein binding; single-stranded DNA binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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