Rhesus Macaque rmIP10 Active Protein – Cat# MBS146259

Ip-10 (rmIP10) Rhesus Macaque Active Protein

Name: rmIP10 Active Protein; Ip-10; Rhesus Macaque; MyBioSource
Brand: MyBioSource
SKU: MBS146259
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146259

Description: IP-10 Rhesus macaque Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of 8.7kDa. The IP-10 is purified by proprietary chromatographic techniques.Introduction:… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IP-10 (rmIP10), Active Protein

Full Product Name

Recombinant Rhesus macaque IP-10 (CXCL10)

Product Gene Name

rmIP10 active protein

Product Synonym Names

IP 10 Rhesus macaque; IP-10 Rhesus macaque Recombinant (CXCL10); C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; Small-inducible cytokine B10; CXCL10; SCYB10

Sequence

IPLSRTVRCT CISISNQPVN PRSLEKLEII PPSQFCPHVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP

Host

E Coli

Form/Format

Lyophilized from a 0.2 um filtered concentrated solution in 1xPBS, pH 7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Preparation and Storage

Lyophilized IP-10 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CXCL10 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Molecular Weight

10,888 Da

3D Structure

ModBase 3D Structure for Q8MIZ1

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Solubility

It is recommended to reconstitute the lyophilized IP-10 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Biological Activity

Determined by its ability to chemoattract human peripheral blood T-Lymphocytes using a concentration range of 10.0-100.0 ng/ml.

Product Categories/Family for rmIP10 active protein

Chemokines; IP-10 (CXCL10)

Other Notes

Small volumes of rmIP10 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for rmIP10 purchase

MBS146259 is an active protein targeting rmIP10. Also known as Recombinant Rhesus macaque IP-10 (CXCL10). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for rmIP10. It may not necessarily be applicable to this product.

NCBI GI #

74136347

NCBI GeneID

574243

NCBI Accession #

NP_001028064.1

UniProt Primary Accession #

Q8MIZ1

UniProt Related Accession #

Q8MIZ1

GenBank Nucleotide #

NM_001032892.1

NCBI Official Full Name

C-X-C motif chemokine 10

NCBI Official Symbol

CXCL10

UniProt Protein Name

C-X-C motif chemokine 10

UniProt Synonym Protein Names

10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; Small-inducible cytokine B10

UniProt Gene Name

CXCL10

UniProt Synonym Gene Names

SCYB10; Gamma-IP10; IP-10

UniProt Entry Name

CXL10_MACMU

NCBI Protein Information

C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein; 10 kDa interferon-gamma-induced protein; 10 kDa interferon-gamma-inducible protein CXCL10; IP-10; gamma-IP10; small inducible cytokine B10; small-inducible cytokine B10

UniProt Comments for rmIP10

Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with rmIP10 active protein

Reference Product	PubMed Publications
CXCR3 active protein	>827 publications with rmIP10 and CXCR3
CCL5 active protein	>641 publications with rmIP10 and CCL5
CCR7 active protein	>75 publications with rmIP10 and CCR7
CCR4 active protein	>61 publications with rmIP10 and CCR4
CCR1 active protein	>47 publications with rmIP10 and CCR1
CCR3 active protein	>47 publications with rmIP10 and CCR3
CCR6 active protein	>34 publications with rmIP10 and CCR6
IL8RB active protein	>16 publications with rmIP10 and IL8RB
IL8RA active protein	>10 publications with rmIP10 and IL8RA
CCR2B active protein	>1 publications with rmIP10 and CCR2B

Pathways associated with rmIP10 active protein

Products by Pathway	Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
RIG-I-like Receptor Signaling Pathway antibodies	RIG-I-like Receptor Signaling Pathway Diagram
RIG-I-like Receptor Signaling Pathway antibodies	RIG-I-like Receptor Signaling Pathway Diagram

Diseases associated with rmIP10 active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>1158 publications with rmIP10 and Inflammation
Necrosis Antibodies	>669 publications with rmIP10 and Necrosis
Disease Models, Animal Antibodies	>338 publications with rmIP10 and Disease Models, Animal
Lung Diseases Antibodies	>332 publications with rmIP10 and Lung Diseases
Liver Diseases Antibodies	>229 publications with rmIP10 and Liver Diseases
Cardiovascular Diseases Antibodies	>169 publications with rmIP10 and Cardiovascular Diseases
Fibrosis Antibodies	>126 publications with rmIP10 and Fibrosis
Neoplasms, Experimental Antibodies	>113 publications with rmIP10 and Neoplasms, Experimental
Kidney Diseases Antibodies	>86 publications with rmIP10 and Kidney Diseases
Lung Injury Antibodies	>63 publications with rmIP10 and Lung Injury

Organs/Tissues associated with rmIP10 active protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2017 publications with rmIP10 and Blood
Other Antibodies	>620 publications with rmIP10 and Other