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Semenogelin I (SEMG1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146273

Description: SEMG1 Human Recombinant produced in E Coli is a single polypeptide chain containing 462 amino acids (24-462) and having a molecular mass of 52kDa. SEMG1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Semenogelin I (SEMG1), Recombinant Protein
Full Product Name
Recombinant Human Semenogelin I
Product Gene Name
Product Synonym Names
SEMG1 Human; Semenogelin I Human Recombinant; CT103; dJ172H20.2; SEMG; SGI; Semenogelin-1; Semenogelin I; SEMG1
Sequence
MGSSHHH HHH SSGLVPRGSH MGSQKG GSKG RLPSEFSQFP HGQKGQHYSG QKGKQQTESK GSFSIQYTYH VDANDHDQSR KSQQYDLNAL HKTTKSQRHL GGSQQLLHNK QEGRDHDKSK GHFHRVVIHH KGGKAHRGTQ NPSQDQGNSP SGKGISSQYS NTEERLWVHG LSKEQTSVSG AQKGRKQGGS QSSYVLQTEE LVANKQQRET KNSHQNKGHY QNVVEVREEH SSKVQTSLCP AHQDKLQHGS KDIFSTQDEL LVYNKNQHQT KNLNQDQQHG RKANKISYQS SSTEERRLHY GENGVQKDVS QSSIYSQTEE KAQGKSQKQI TIPSQEQEHS QKANKISYQS SSTEERRLHY GENGVQKDVS QRSIYSQTEK LVAGKSQIQA PNPKQEPWHG ENAKGESGQS TNREQDLLSH EQKGRHQHGS HGGLDIVIIE QEDDSDRHLA QHLNNDRNPL FT
Host
E Coli
Form/Format
The SEMG1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 20% glycerol and 1mM DTT.
Sterile Filtered clear solution.
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Molecular Weight
45,322 Da
OMIM
182140
3D Structure
ModBase 3D Structure for P04279

Other Notes

Small volumes of SEMG1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEMG1 purchase

MBS146273 is a recombinant protein targeting SEMG1. Also known as Recombinant Human Semenogelin I. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SEMG1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
semenogelin-1 preproprotein
NCBI Official Synonym Full Names
semenogelin I
NCBI Official Symbol
SEMG1
NCBI Official Synonym Symbols
SGI; SEMG; CT103; dJ172H20.2
UniProt Protein Name
Semenogelin-1
UniProt Synonym Protein Names
Semenogelin I; SGI
Protein Family
UniProt Gene Name
SEMG1
UniProt Synonym Gene Names
SEMG; SGI
UniProt Entry Name
SEMG1_HUMAN
NCBI Protein Information
semenogelin-1; SgI-29; cancer/testis antigen 103; semen coagulating protein

NCBI Summary for SEMG1

The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely. The antimicrobial peptide SgI-29 is an antimicrobial peptide with antibacterial activity. [provided by RefSeq, Nov 2014]
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UniProt Comments for SEMG1

SEMG1: Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA. Belongs to the semenogelin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cancer Testis Antigen (CTA); Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20q12-q13.2

Cellular Component: extracellular space; extracellular region; nucleus; secretory granule

Molecular Function: protein binding; structural molecule activity

Biological Process: insemination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SEMG1 recombinant protein

Organs/Tissues associated with SEMG1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >5 publications with SEMG1 and Prostate
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