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Canopy 3 Homolog (CNPY3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146290

Description: CNPY3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 271 amino acids (31-278 a.a.) and having a molecular mass of 29.9kDa. CNPY3 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Canopy 3 Homolog (CNPY3), Recombinant Protein
Full Product Name
Recombinant Human Canopy 3 Homolog
Product Gene Name
Product Synonym Names
CNPY3 Human; Canopy 3 Homolog Human Recombinant; CAG4A; ERDA5; PRAT4A; TNRC5; Protein canopy homolog 3; CTG repeat protein 4a; Expanded repeat-domain protein CAG/CTG 5; Protein associated with TLR4; Trinucleotide repeat-containing gene 5 protein; CNPY3
Sequence
MGSSHHH HHH SSGLVPRGSH MGSGPS QAGA EENDWVRLPS KCEVCKYVAV ELKSAFEETG KTKEVIGTGY GILDQKASGV KYTKSDLRLI EVTETICKRL LDYSLHKERT GSNRFAKGMS ETFETLHNLV HKGVKVVMDI PYELWNETSA EVADLKKQCD VLVEEFEEVI EDWYRNHQEE DLTEFLCANH VLKGKDTSCL AEQWSGKKGD TAALGGKKSK KKSSRAKAAG GRSSSSKQRK ELGGLEGDPS PEEDEGIQKA SPLTHSPPDE L
Host
E Coli
Form/Format
CNPY3 protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Molecular Weight
5,773 Da
OMIM
610774
3D Structure
ModBase 3D Structure for Q9BT09

Other Notes

Small volumes of CNPY3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CNPY3 purchase

MBS146290 is a recombinant protein targeting CNPY3. Also known as Recombinant Human Canopy 3 Homolog. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CNPY3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein canopy homolog 3
NCBI Official Synonym Full Names
canopy FGF signaling regulator 3
NCBI Official Symbol
CNPY3
NCBI Official Synonym Symbols
CAG4A; ERDA5; TNRC5; PRAT4A
UniProt Protein Name
Protein canopy homolog 3
UniProt Synonym Protein Names
CTG repeat protein 4a; Expanded repeat-domain protein CAG/CTG 5; Protein associated with TLR4; Trinucleotide repeat-containing gene 5 protein
Protein Family
UniProt Gene Name
CNPY3
UniProt Synonym Gene Names
CTG4A; ERDA5; PRAT4A; TNRC5
UniProt Entry Name
CNPY3_HUMAN
NCBI Protein Information
protein canopy homolog 3; CAG repeat containing; CTG repeat protein 4a; canopy 3 homolog; expanded repeat domain, CAG/CTG 5; expanded repeat-domain protein CAG/CTG 5; protein associated with TLR4; protein associated with Toll-like receptor 4A; trinucleotide repeat containing 5; trinucleotide repeat-containing gene 5 protein

NCBI Summary for CNPY3

PRAT4A is associated with the immature form of TLR4 (MIM 603030) and regulates its cell surface expression (Wakabayashi et al., 2006 [PubMed 16849487]).[supplied by OMIM, Mar 2008]

UniProt Comments for CNPY3

TNRC5: Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptative immune responses. Belongs to the canopy family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: endoplasmic reticulum lumen

Molecular Function: receptor binding

Biological Process: toll-like receptor signaling pathway; innate immune response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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