Human PLSCR1 Recombinant Protein – Cat# MBS146295

Phospholipid Scramblase 1 (PLSCR1) Human Recombinant Protein

Name: PLSCR1 Recombinant Protein; Phospholipid Scramblase 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS146295
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146295

Description: PLSCR1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 308 amino acids (1-288 a.a.) and having a molecular mass of 33.8kDa.PLSCR1 is fused to a 20 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Phospholipid Scramblase 1 (PLSCR1), Recombinant Protein

Full Product Name

Recombinant Human Phospholipid Scramblase 1

Product Gene Name

PLSCR1 recombinant protein

Product Synonym Names

PLSCR1 Human; Phospholipid Scramblase 1 Protein Human Recombinant; MMTRA1B; Phospholipid scramblase 1; PL scramblase 1; Ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; MmTRA1b

Sequence

MGSSHHH HHH SSGLVPRGSH MDKQNSQMNA SHPETNLPVG YPPQYPPTAF QGPPGYSGYP GPQVSYPPPP AGHSGPGPAG FPVPNQPVYN QPVYNQPVGA AGVPWMPAPQ PPLNCPPGLE YLSQIDQILI HQQIELLEVL TGFETNNKYE IKNSFGQRVY FAAEDTDCCT RNCCGPSRPF TLRIIDNMGQ EVITLERPLR CSSCCCPCCL QEIEIQAPPG VPIGYVIQTW HPCLPKFTIQ NEKREDVLKI SGPCVVCSCC GDVDFEIKSL DEQCVVGKIS KHWTGILREA FTDADNFGIQ FPLDLDVK

Host

E Coli

Form/Format

PLSCR1 protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl,30% glycerol and 1mM DTT.
Sterile Filtered clear solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Molecular Weight

26,825 Da

OMIM

604170

3D Structure

ModBase 3D Structure for O15162

Product Categories/Family for PLSCR1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of PLSCR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLSCR1 purchase

MBS146295 is a recombinant protein targeting PLSCR1. Also known as Recombinant Human Phospholipid Scramblase 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PLSCR1. It may not necessarily be applicable to this product.

NCBI GI #

10863877

NCBI GeneID

5359

NCBI Accession #

NP_066928.1

UniProt Primary Accession #

O15162

UniProt Secondary Accession #

B2R8H8; B4DTE8

UniProt Related Accession #

O15162

GenBank Nucleotide #

NM_021105.2

NCBI Official Full Name

phospholipid scramblase 1

NCBI Official Synonym Full Names

phospholipid scramblase 1

NCBI Official Symbol

PLSCR1

NCBI Official Synonym Symbols

MMTRA1B

UniProt Protein Name

Phospholipid scramblase 1

UniProt Synonym Protein Names

Ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; MmTRA1b

Protein Family

Phospholipid scramblase

UniProt Gene Name

PLSCR1

UniProt Synonym Gene Names

PL scramblase 1

UniProt Entry Name

PLS1_HUMAN

NCBI Protein Information

phospholipid scramblase 1; PL scramblase 1; ca(2+)-dependent phospholipid scramblase 1; erythrocyte phospholipid scramblase

UniProt Comments for PLSCR1

PLSCR1: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family.

Protein type: Calcium-binding; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q23

Cellular Component: Golgi apparatus; extracellular matrix; membrane; integral to plasma membrane; plasma membrane; nucleolus; nucleus; cytosol; lipid raft

Molecular Function: phospholipid scramblase activity; protein binding; enzyme binding; DNA binding; calcium ion binding; CD4 receptor binding; SH3 domain binding; epidermal growth factor receptor binding

Biological Process: platelet activation; negative regulation of viral genome replication; apoptosis; positive regulation of innate immune response; acute-phase response; positive regulation of transcription from RNA polymerase II promoter; phospholipid scrambling; defense response to virus; regulation of mast cell activation; phosphatidylserine biosynthetic process

Research Articles on PLSCR1

1. affinity of SCR for cholesterol-rich domains in membranes

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PLSCR1 recombinant protein

Reference Product	PubMed Publications
SRC recombinant protein	>8 publications with PLSCR1 and SRC
CD4 recombinant protein	>1 publications with PLSCR1 and CD4
OXSR1 recombinant protein	>1 publications with PLSCR1 and OXSR1
ITPR1 recombinant protein	>1 publications with PLSCR1 and ITPR1
SHC1 recombinant protein	>1 publications with PLSCR1 and SHC1
BACE1 recombinant protein	>1 publications with PLSCR1 and BACE1

Pathways associated with PLSCR1 recombinant protein

Products by Pathway	Pathway Diagram
EGFR1 Signaling Pathway antibodies	EGFR1 Signaling Pathway Diagram

Diseases associated with PLSCR1 recombinant protein

Disease Name	Pubmed Publications
Hepatitis Antibodies	>5 publications with PLSCR1 and Hepatitis
Liver Diseases Antibodies	>4 publications with PLSCR1 and Liver Diseases
Inflammation Antibodies	>4 publications with PLSCR1 and Inflammation
Cardiovascular Diseases Antibodies	>4 publications with PLSCR1 and Cardiovascular Diseases
Carcinoma, Hepatocellular Antibodies	>3 publications with PLSCR1 and Carcinoma, Hepatocellular
Brain Diseases Antibodies	>2 publications with PLSCR1 and Brain Diseases
Necrosis Antibodies	>2 publications with PLSCR1 and Necrosis
Ovarian Neoplasms Antibodies	>2 publications with PLSCR1 and Ovarian Neoplasms
Liver Neoplasms Antibodies	>2 publications with PLSCR1 and Liver Neoplasms
Hypertrophy Antibodies	>1 publications with PLSCR1 and Hypertrophy

Organs/Tissues associated with PLSCR1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>24 publications with PLSCR1 and Blood
Bone Antibodies	>6 publications with PLSCR1 and Bone
Liver Antibodies	>6 publications with PLSCR1 and Liver
Bone Marrow Antibodies	>5 publications with PLSCR1 and Bone Marrow
Adipose Tissue Antibodies	>3 publications with PLSCR1 and Adipose Tissue
Connective Tissue Antibodies	>3 publications with PLSCR1 and Connective Tissue
Brain Antibodies	>2 publications with PLSCR1 and Brain
Muscle Antibodies	>2 publications with PLSCR1 and Muscle
Vascular Antibodies	>2 publications with PLSCR1 and Vascular
Kidney Antibodies	>2 publications with PLSCR1 and Kidney