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3-Oxoacyl-ACP Synthase (OXSM) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146358

Description: OXSM Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 455 amino acids (28-459) and having a molecular mass of 48.1kDa.OXSM is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary… More details

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Product Overview

Online Datasheet in PDF
Product Name
3-Oxoacyl-ACP Synthase (OXSM), Recombinant Protein
Full Product Name
Recombinant Human 3-Oxoacyl-ACP Synthase, Mitochondrial
Product Gene Name
Product Synonym Names
OXSM Human; 3-Oxoacyl-ACP Synthase, Mitochondrial Human Recombinant; 3-Oxoacyl-ACP Synthase Mitochondrial; Type II Mitochondrial Beta-Ketoacyl Synthase; 3-Ketoacyl-Acyl Carrier Protein Synthase; FASN2D; KASI; EC 2.3.1; Beta-Ketoacyl-ACP Synthase
Sequence
MGSSHHH HHH SSGLVPRGSH MGSKRK FFGT VPISRLHRRV VITGIGLVTP LGVGTHLVWD RLIGGESGIV SLVGEEYKSI PCSVAAYVPR GSDEGQFNEQ NFVSKSDIKS MSSPTIMAIG AAELAMKDSG WHPQSEADQV ATGVAIGMGM IPLEVVSETA LNFQTKGYNK VSPFFVPKIL VNMAAGQVSI RYKLKGPNHA VSTACTTGAH AVGDSFRFIA HGDADVMVAG GTDSCISPLS LAGFSRARAL STNSDPKLAC RPFHPKRDGF VMGEGAAVLV LEEYEHAVQR RARIYAEVLG YGLSGDAGHI TAPDPEGEGA LRCMAAALKD AGVQPEEISY INAHATSTPL GDAAENKAIK HLFKDHAYAL AVSSTKGATG HLLGAAGAVE AAFTTLACYY QKLPPTLNLD CSEPEFDLNY VPLKAQEWKT EKRFIGLTNS FGFGGTNATL CIAGL.
Host
E Coli
Form/Format
The OXSM solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.15M NaCl, 1mM DTT and 10% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Molecular Weight
40,035 Da
OMIM
610324
3D Structure
ModBase 3D Structure for Q9NWU1

Product Categories/Family for OXSM recombinant protein

Other Notes

Small volumes of OXSM recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OXSM purchase

MBS146358 is a recombinant protein targeting OXSM. Also known as Recombinant Human 3-Oxoacyl-ACP Synthase, Mitochondrial. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for OXSM. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial isoform 2
NCBI Official Synonym Full Names
3-oxoacyl-ACP synthase, mitochondrial
NCBI Official Symbol
OXSM
NCBI Official Synonym Symbols
KS; KASI; FASN2D
UniProt Protein Name
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
UniProt Synonym Protein Names
Beta-ketoacyl-ACP synthase
UniProt Gene Name
OXSM
UniProt Entry Name
OXSM_HUMAN
NCBI Protein Information
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; 3-ketoacyl-acyl carrier protein synthase; 3-oxoacyl-acyl-carrier-protein synthase; acyl-malonyl acyl carrier protein-condensing enzyme; beta-ketoacyl synthase; beta-ketoacyl-ACP synthase; type II mitochondrial beta-ketoacyl synthase

NCBI Summary for OXSM

This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]

UniProt Comments for OXSM

OXSM: May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the beta-ketoacyl-ACP synthases family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.3.1.41; Lipid Metabolism - fatty acid biosynthesis; Mitochondrial

Chromosomal Location of Human Ortholog: 3p24.2

Cellular Component: mitochondrion; cytoplasm

Molecular Function: 3-oxoacyl-[acyl-carrier-protein] synthase activity

Biological Process: medium-chain fatty acid biosynthetic process; acyl-CoA metabolic process; short-chain fatty acid biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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