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Transforming Growth Factor Beta Receptor Associated Protein 1 (TGFBRAP1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146374

Description: TGFBRAP1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 296 amino acids (601-860 a.a) and having a molecular mass of 33kDa.TGFBRAP1 is fused to a 36 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Transforming Growth Factor Beta Receptor Associated Protein 1 (TGFBRAP1), Recombinant Protein
Full Product Name
Recombinant Human Transforming Growth Factor Beta Receptor Associated Protein 1
Product Synonym Names
TGFBRAP1 Human; Transforming Growth Factor Beta Receptor Associated Protein 1 Human Recombinant; TRAP-1; TRAP1; Transforming growth factor-beta receptor-associated protein 1; TGF-beta receptor-associated protein 1
Sequence
MRGSHHH HHH GMASMTGGQQ MGRDLYDDDD KDRWGS KRLQ KEEYHTHLAV LYLEEVLLQR ASASGKGAEA TETQAKLRRL LQKSDLYRVH FLLERLQGAG LPMESAILHG KLGEHEKALH ILVHELQDFA AAEDYCLWCS EGRDPPHRQQ LFHTLLAIYL HAGPTAHELA VAAVDLLNRH ATEFDAAQVL QMLPDTWSVQ LLCPFLMGAM RDSIHARRTM QVALGLARSE NLIYTYDKMK LKGSSIQLSD KKLCQICQNP FCEPVFVRYP NGGLVHTHCA ASRHTNPSSS SPGTRT
Host
E Coli
Form/Format
TGFBRAP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 80% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Molecular Weight
97,158 Da
OMIM
606237
3D Structure
ModBase 3D Structure for Q8WUH2

Other Notes

Small volumes of TGFBRAP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TGFBRAP1 purchase

MBS146374 is a recombinant protein targeting TGFBRAP1. Also known as Recombinant Human Transforming Growth Factor Beta Receptor Associated Protein 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TGFBRAP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transforming growth factor-beta receptor-associated protein 1
NCBI Official Synonym Full Names
transforming growth factor, beta receptor associated protein 1
NCBI Official Symbol
TGFBRAP1
NCBI Official Synonym Symbols
TRAP1; TRAP-1
UniProt Protein Name
Transforming growth factor-beta receptor-associated protein 1
UniProt Gene Name
TGFBRAP1
UniProt Synonym Gene Names
TGF-beta receptor-associated protein 1; TRAP-1; TRAP1
UniProt Entry Name
TGFA1_HUMAN
NCBI Protein Information
transforming growth factor-beta receptor-associated protein 1; TGF beta receptor associated protein -1; TGF-beta receptor-associated protein 1

UniProt Comments for TGFBRAP1

TGFBRAP1: Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. Belongs to the TRAP1 family.

Chromosomal Location of Human Ortholog: 2q12.1

Cellular Component: membrane; cytoplasm

Molecular Function: protein binding; SMAD binding; transforming growth factor beta receptor binding

Biological Process: vesicle-mediated transport; intracellular protein transport; regulation of transcription, DNA-dependent; regulation of catalytic activity; transforming growth factor beta receptor signaling pathway; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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