Mouse mIL36G Active Protein – Cat# MBS146376

Interleukin-36 Gamma (mIL36G) Mouse Active Protein

Name: mIL36G Active Protein; Interleukin-36 Gamma; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS146376
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146376

Description: IL36G Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 152 amino acids and having a molecular mass of 17.3kDa.The IL36G is purified by proprietary chromatographic techniques.Introduction: IL-36gamma… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Interleukin-36 Gamma (mIL36G), Active Protein

Full Product Name

Recombinant Mouse Interleukin-36 Gamma

Product Gene Name

mIL36G active protein

Product Synonym Names

IL36G Mouse; Interleukin-36 Gamma Mouse Recombinant; Interleukin-36 gamma; Interleukin-1 family member 9; IL-1F9; Il36g; Il1f9

Sequence

GRETPDFGEV FDLDQQVWIF RNQALVTVPR SHRVTPVSVT ILPCKYPESL EQDKGIAIYL GIQNPDKCLF CKEVNGHPTL LLKEEKILDL YHHPEPMKPF LFYHTRTGGT STFESVAFPG HYIASSKTGN PIFLTSKKGE YYNINFNLDI KS

Host

E Coli

Form/Format

Lyophilized from a 0.2 um filtered concentrated solution in 20mM Tris-HCl, pH 8.5, 150mM NaCl and Tween-20.
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Preparation and Storage

Lyophilized IL36g Mouse although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IL36g should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.

Molecular Weight

18,733 Da

3D Structure

ModBase 3D Structure for Q8R460

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Solubility

It is recommended to reconstitute the lyophilized IL36g in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Biological Activity

The ED50 as determined by inducing IL-6 secretion in murine NIH/3T3 cells is less than 10 ng/ml, corresponding to a specific activity of > 1.0x105 IU/mg.

Product Categories/Family for mIL36G active protein

Cytokines and Growth Factors; Cytokines; Interleukin

Other Notes

Small volumes of mIL36G active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for mIL36G purchase

MBS146376 is an active protein targeting mIL36G. Also known as Recombinant Mouse Interleukin-36 Gamma. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for mIL36G. It may not necessarily be applicable to this product.

NCBI GI #

25008588

NCBI Accession #

Q8R460.1

UniProt Primary Accession #

Q8R460

UniProt Secondary Accession #

Q14BB6

NCBI Official Full Name

Interleukin-36 gamma

UniProt Protein Name

Interleukin-36 gamma

UniProt Synonym Protein Names

Interleukin-1 family member 9; IL-1F9

Protein Family

Interleukin

UniProt Gene Name

Il36g

UniProt Synonym Gene Names

Il1f9; IL-1F9

UniProt Entry Name

IL36G_MOUSE

UniProt Comments for mIL36G

Functions as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2/IL1RL2. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP (). Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. May play a role in proinflammatory responses during particular neutrophilic airway inflammation. May be involved in the innate immune response to fungal pathogens. Induces the production of proinflammatory cytokines in bone marrow-derived dendritic cells (BMDCs), including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23. Involved in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II. Induces the production of IFN-gamma, IL-4 and IL-17 by cultured CD4+ T-cells and splenocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.