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Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase (TACO1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146405

Description: TACO1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 260 amino acids (61-297 a.a) and having a molecular mass of 28.8kDa.TACO1 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase (TACO1), Recombinant Protein
Full Product Name
Recombinant Human Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase
Product Gene Name
Product Synonym Names
TACO1 Human; Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase Human Recombinant; Translational Activator Of Mitochondrially Encoded Cytochrome C Oxidase; CCDC44; Coiled-Coil Domain-Containing Protein 44; Coiled-Coil Domain Containing 44; Clone HQ0477 PRO0477p; Translational Activator Of Cytochrome C Oxidase 1; Translational Activator Of Mitochondrially-Encoded Cytochrome C Oxidase I
Sequence
MGSSHHH HHH SSGLVPRGSH MGSNKW SKVR HIKGPKDVER SRIFSKLCLN IRLAVKEGGP NPEHNSNLAN ILEVCRSKHM PKSTIETALK MEKSKDTYLL YEGRGPGGSS LLIEALSNSS HKCQADIRHI LNKNGGVMAV GARHSFDKKG VIVVEVEDRE KKAVNLERAL EMAIEAGAED VKETEDEEER NVFKFICDAS SLHQVRKKLD SLGLCSVSCA LEFIPNSKVQ LAEPDLEQAA HLIQALSNHE DVIHVYDNIE
Host
E Coli
Form/Format
TACO1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered clear solution.
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Molecular Weight
32,477 Da
OMIM
256000
3D Structure
ModBase 3D Structure for Q9BSH4

Other Notes

Small volumes of TACO1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TACO1 purchase

MBS146405 is a recombinant protein targeting TACO1. Also known as Recombinant Human Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TACO1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
translational activator of cytochrome c oxidase 1
NCBI Official Synonym Full Names
translational activator of mitochondrially encoded cytochrome c oxidase I
NCBI Official Symbol
TACO1
NCBI Official Synonym Symbols
CCDC44
UniProt Protein Name
Translational activator of cytochrome c oxidase 1
UniProt Synonym Protein Names
Coiled-coil domain-containing protein 44; Translational activator of mitochondrially-encoded cytochrome c oxidase I
UniProt Gene Name
TACO1
UniProt Synonym Gene Names
CCDC44
UniProt Entry Name
TACO1_HUMAN
NCBI Protein Information
translational activator of cytochrome c oxidase 1; clone HQ0477 PRO0477p; coiled-coil domain-containing protein 44

NCBI Summary for TACO1

This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010]

UniProt Comments for TACO1

CCDC44: Acts as a translational activator of mitochondrially- encoded cytochrome c oxidase 1. Defects in TACO1 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency. Belongs to the TACO1 family.

Chromosomal Location of Human Ortholog: 17q23.3

Cellular Component: nucleoplasm; mitochondrion; nucleus

Biological Process: regulation of translation

Disease: Mitochondrial Complex Iv Deficiency
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TACO1 recombinant protein

 Reference Product  PubMed Publications
 COX10 recombinant protein  >1 publications with TACO1 and COX10

Organs/Tissues associated with TACO1 recombinant protein

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