• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Receptor-Type Tyrosine-Protein Phosphatase U (PTPRU) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1464088

MBS1464088 is a recombinant protein targeting PTPRU. Also known as Recombinant Human Receptor-type tyrosine-protein phosphatase U (PTPRU), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$2100 / 0.5 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Receptor-type tyrosine-protein phosphatase U (PTPRU), Recombinant Protein
Full Product Name
Recombinant Human Receptor-type tyrosine-protein phosphatase U (PTPRU), partial
Product Gene Name
PTPRU recombinant protein
Product Synonym Gene Name
PTPRU
Sequence
ET ETPAAGCTFE EASDPAVPCE YSQAQYDDFQ WEQVRIHPGT RAPADLPHGS YLMVNTSQHA PGQRAHVIFQ SLSENDTHCV QFSYFLYSRD GHSPGTLGVY VRVNGGPLGS AVWNMTGSHG RQWHQAELAV STFWPNEYQV LFEALISPDR RGYMGLDDIL LLSYPCAKAP HFSRLGDVEV NAGQNASFQC MAAGRAAEAE RFLLQRQSGA LVPAAGVRHI SHRRFLATFP LAAVSRAEQD LYRCVSQAPR GAGVSNFAEL IVKEPPTPIA PPQLLRAGPT YLIIQLNTNS IIGDGPIVRK EIEYRMARGP WAEVHAVSLQ TYKLWHLDPD TEYEISVLLT RPGDGGTGRP GPPLISRTKC AEPMRAPKGL AFAEIQARQL TLQWEPLGYN VTRCHTYTVS LCYHYTLGSS HNQTIRECVK TEQGVSRYTI KNLLPYRNVH VRLVLTNPEG RKEGKEVTFQ TDEDVPSGIA AESLTFTPLE DMIFLKWEEP QEPNGLITQY EISYQSIESS DPAVNVPGPR RTISKLRNET YHVFSNLHPG TTYLFSVRAR TGKGFGQAAL TEITTNISAP SFDYADMPSP LGESENTITV LLRPAQGRGA PISVYQVIVE EERARRLRRE PGGQDCFPVP LTFEAALARG LVHYFGAELA ASSLPEAMPF TVGDNQTYRG FWNPPLEPRK AYLIYFQAAS HLKGETRLNC IRIARKAACK ESKRPLEVSQ RSEEMGLIL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
161,648 Da
Sequence Positions
19-749
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
602454
3D Structure
ModBase 3D Structure for Q92729
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PTPRU recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPRU. It may not necessarily be applicable to this product.

NCBI GI #
303304997
NCBI GeneID
10076
NCBI Accession #
NP_001181930.1
UniProt Primary Accession #
Q92729
UniProt Secondary Accession #
O00197; P78399; Q59HA4; Q5SYU4; Q5SYU5; Q92735; Q92850; A6H8L1
UniProt Related Accession #
Q92729
GenBank Nucleotide #
NM_001195001.1
NCBI Official Full Name
receptor-type tyrosine-protein phosphatase U isoform 4
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type U
NCBI Official Symbol
PTPRU
NCBI Official Synonym Symbols
FMI; PTP; PCP-2; PTP-J; PTPRO; PTPU2; PTP-PI; PTP-RO; PTPPSI; hPTP-J; R-PTP-U; R-PTP-PSI
UniProt Protein Name
Receptor-type tyrosine-protein phosphatase U
UniProt Synonym Protein Names
Pancreatic carcinoma phosphatase 2; PCP-2; Protein-tyrosine phosphatase J; PTP-J; hPTP-J; Protein-tyrosine phosphatase pi; PTP pi; Protein-tyrosine phosphatase receptor omicron; PTP-RO; Receptor-type protein-tyrosine phosphatase psi; R-PTP-psi
Protein Family
Receptor-type tyrosine-protein phosphatase
UniProt Gene Name
PTPRU
UniProt Synonym Gene Names
FMI; PCP2; PTPRO; R-PTP-U; PCP-2; PTP-J; hPTP-J; PTP pi; PTP-RO; R-PTP-psi
NCBI Protein Information
receptor-type tyrosine-protein phosphatase U

NCBI Summary for PTPRU

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported. [provided by RefSeq, Aug 2010]
Show more

UniProt Comments for PTPRU

Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis.

Research Articles on PTPRU

1. PTPRU is required for gastric cancer cell proliferation and migration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PTPRU recombinant protein

 Products by Pathway  Pathway Diagram
 EPO Receptor Signaling Pathway antibodies  EPO Receptor Signaling Pathway Diagram
 Kit Receptor Signaling Pathway antibodies  Kit Receptor Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By SCF-KIT Pathway antibodies  Signaling By SCF-KIT Pathway Diagram

Diseases associated with PTPRU recombinant protein

 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >3 publications with PTPRU and Lung Diseases
 Nervous System Diseases Antibodies  >2 publications with PTPRU and Nervous System Diseases
 Brain Diseases Antibodies  >1 publications with PTPRU and Brain Diseases
 Inflammation Antibodies  >1 publications with PTPRU and Inflammation

Organs/Tissues associated with PTPRU recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >5 publications with PTPRU and Lung
 Brain Antibodies  >5 publications with PTPRU and Brain
 Kidney Antibodies  >3 publications with PTPRU and Kidney
 Bone Antibodies  >2 publications with PTPRU and Bone
 Bone Marrow Antibodies  >2 publications with PTPRU and Bone Marrow
 Ganglia Antibodies  >1 publications with PTPRU and Ganglia
 Prostate Antibodies  >1 publications with PTPRU and Prostate
 Muscle Antibodies  >1 publications with PTPRU and Muscle
 Testis Antibodies  >1 publications with PTPRU and Testis
 Embryonic Tissue Antibodies  >1 publications with PTPRU and Embryonic Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000