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B-Cell Receptor CD22 (CD22) Pan Paniscus Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1464254

MBS1464254 is a recombinant protein targeting CD22. Also known as Recombinant Pan paniscus B-cell receptor CD22 (CD22). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1015 / 0.05 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
B-cell receptor CD22 (CD22), Recombinant Protein
Full Product Name
Recombinant Pan paniscus B-cell receptor CD22 (CD22)
Product Gene Name
Product Synonym Gene Name
CD22; SIGLEC2
Product Synonym Names
B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2; Siglec-2; CD_antigen=; CD22
Sequence
D SSKWAFEHPE TLYAWEGACV WIPCTYRALD RDLESFILFH NPEYNKNTSK FDGTRLYEST EDGKVPSEQK RVQFLGDKNK NCTLSIHPVH VNDSGQLGLR MESKTAKWME RIHLNVSERP FPPHIQLPPE IQESQEVTLT CLLNFSCYGY PIQLQWLLEG VPMRQAAVTS TSLTIKSVFT RSELKFSPQW SHHGKIVTCQ LQDADGKFLS NDTVQLNVKH TPKLEIKVTP SDAIVREGES VTMTCEVSSS NPEYTTISWL KDGTSLKKQN TLMLNLHEVT KDQSGKYCCQ VSNDVGPGRS AEVFLQVQYA PE
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
37,757 Da
Sequence Positions
20-332aa; Extracellular domain
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9N1E5
Species
Pan paniscus (Pygmy chimpanzee) (Bonobo)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CD22 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD22. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
B-cell receptor CD22
NCBI Official Symbol
CD22
NCBI Official Synonym Symbols
SIGLEC2; siglec-2
UniProt Protein Name
B-cell receptor CD22
UniProt Synonym Protein Names
Sialic acid-binding Ig-like lectin 2; Siglec-2; CD_antigen: CD22
Protein Family
UniProt Gene Name
CD22
UniProt Synonym Gene Names
SIGLEC2; Siglec-2
UniProt Entry Name
CD22_PANPA
NCBI Protein Information
CD22 molecule; Sialic acid-binding Ig-like lectin 2

UniProt Comments for CD22

Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid (). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling cascade key molecules.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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