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Uteroglobin (rSCGB1A1) Rat Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146434

Description: SCGB1A1 Rat Recombinant produced in E Coli is a homodimeric non-glycosylated polypeptide chains consisting of two 77 amino acids and having a molecular mass of 17.0kDa. Introduction: Uteroglobin (SCGB1A1) which belongs to the Secretoglobin… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Uteroglobin (rSCGB1A1), Active Protein
Full Product Name
Recombinant Rat Uteroglobin
Product Gene Name
rSCGB1A1 active protein
Product Synonym Names
SCGB1A1 Rat; Uteroglobin Rat Recombinant; Uteroglobin; Clara cell 17 kDa protein; Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; PCB-binding protein; Secretoglobin family 1A member 1; Scgb1a1; Ugb; Utg; UG; CC16; CCSP; PCB-BP
Sequence
SSDICPGFLQ VLEALLLGSE SNYEAALKPF NPASDLQNAG TQLKRLVDTL PQETRINIVK LTEKILTSPL CEQDLRV&nb sp;
Host
E Coli
Form/Format
SCGB1A1 protein was lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity/Purification
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Preparation and Storage
Lyophilized SCGB1A1 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution SCGB1A1 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Molecular Weight
10,449 Da
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Solubility
It is recommended to reconstitute the lyophilized SCGB1A1 in sterile 18M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
Fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 ?g/ml, corresponding to a specific activity of >200IU/mg.

Product Categories/Family for rSCGB1A1 active protein

Cytokines and Growth Factors; Cytokines; Uteroglobin

Other Notes

Small volumes of rSCGB1A1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for rSCGB1A1 purchase

MBS146434 is an active protein targeting rSCGB1A1. Also known as Recombinant Rat Uteroglobin. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for rSCGB1A1. It may not necessarily be applicable to this product.

NCBI GI #
6981694
NCBI GeneID
25575
NCBI Accession #
NP_037183
UniProt Related Accession #
P17559
GenBank Nucleotide #
NM_013051.1
NCBI Official Full Name
uteroglobin
NCBI Official Synonym Full Names
secretoglobin, family 1A, member 1 (uteroglobin)
NCBI Official Symbol
Scgb1a1
NCBI Official Synonym Symbols
Ugb; CC10; CCSP; PCBB
UniProt Protein Name
Uteroglobin
UniProt Synonym Protein Names
Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; PCB-binding protein; Secretoglobin family 1A member 1
Protein Family
Uteroglobin
UniProt Gene Name
Scgb1a1
UniProt Synonym Gene Names
Cc10; Ugb; Utg; CCPBP; CC10
UniProt Entry Name
UTER_RAT
NCBI Protein Information
uteroglobin; CCPBP; PCB-binding protein; Uteroglobin (Clara cell secretory protein); clara cell phospholipid-binding protein; clara cells 10 kDa secretory protein; secretoglobin family 1A member 1

NCBI Summary for rSCGB1A1

binds polychlorinated biphenyls [RGD, Feb 2006]

UniProt Comments for rSCGB1A1

SCGB1A1: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Belongs to the secretoglobin family.

Protein type: Cell cycle regulation; Endoplasmic reticulum; Nuclear envelope; Vesicle; Inhibitor; Secreted; Secreted, signal peptide

Cellular Component: extracellular space; rough endoplasmic reticulum; endoplasmic reticulum; cytoplasm; nuclear envelope; intracellular; secretory granule

Molecular Function: phospholipase A2 inhibitor activity

Biological Process: response to drug; negative regulation of interleukin-4 production; response to glucocorticoid stimulus; response to lipopolysaccharide; negative regulation of transcription from RNA polymerase II promoter; regulation of mRNA stability; signal transduction; response to organic substance; response to xenobiotic stimulus; negative regulation of interleukin-13 production; response to silicon dioxide; negative regulation of T cell proliferation; response to ozone; negative regulation of interferon-gamma production; response to cytokine stimulus; negative regulation of catalytic activity; regulation of inflammatory response; negative regulation of interleukin-5 production
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Research Articles on rSCGB1A1

1. Silica exposure causes dynamic changes of SP-D and CC16 protein expression in lung tissue and bronchoalveolar lavage fluid.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with rSCGB1A1 active protein

 Reference Product  PubMed Publications
 Foxa2 active protein  >10 publications with rSCGB1A1 and Foxa2
 Foxa1 active protein  >9 publications with rSCGB1A1 and Foxa1
 Scgb3a2 active protein  >5 publications with rSCGB1A1 and Scgb3a2
 Scgb3a1 active protein  >2 publications with rSCGB1A1 and Scgb3a1
 Spdef active protein  >2 publications with rSCGB1A1 and Spdef
 Sftpa1 active protein  >1 publications with rSCGB1A1 and Sftpa1
 Sftpb active protein  >1 publications with rSCGB1A1 and Sftpb
 Prl active protein  >1 publications with rSCGB1A1 and Prl

Pathways associated with rSCGB1A1 active protein

 Products by Pathway  Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram

Diseases associated with rSCGB1A1 active protein

 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >297 publications with rSCGB1A1 and Lung Diseases
 Inflammation Antibodies  >139 publications with rSCGB1A1 and Inflammation
 Lung Injury Antibodies  >133 publications with rSCGB1A1 and Lung Injury
 Asthma Antibodies  >78 publications with rSCGB1A1 and Asthma
 Lung Neoplasms Antibodies  >58 publications with rSCGB1A1 and Lung Neoplasms
 Respiration Disorders Antibodies  >39 publications with rSCGB1A1 and Respiration Disorders
 Pneumonia Antibodies  >39 publications with rSCGB1A1 and Pneumonia
 Adenocarcinoma Antibodies  >35 publications with rSCGB1A1 and Adenocarcinoma
 Necrosis Antibodies  >34 publications with rSCGB1A1 and Necrosis
 Hyperplasia Antibodies  >32 publications with rSCGB1A1 and Hyperplasia

Organs/Tissues associated with rSCGB1A1 active protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >478 publications with rSCGB1A1 and Lung
 Embryonic Tissue Antibodies  >22 publications with rSCGB1A1 and Embryonic Tissue
 Ovary Antibodies  >1 publications with rSCGB1A1 and Ovary
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