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Sjogren Syndrome/Scleroderma Autoantigen 1 (SSSCA1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146463

Description: SSSCA1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 222 amino acids (1-199aa) and having a molecular mass of 23.9kDa. SSSCA1 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Sjogren Syndrome/Scleroderma Autoantigen 1 (SSSCA1), Recombinant Protein
Full Product Name
Recombinant Human Sjogren Syndrome/Scleroderma Autoantigen 1
Product Synonym Names
SSSCA1 Human; Sjogren Syndrome/Scleroderma Autoantigen 1 Human Recombinant; Sjogren Syndrome/Scleroderma Autoantigen 1; Sjogren'S Syndrome/Scleroderma Autoantigen 1; Autoantigen P27; Centromeric Autoantigen (27kD); p27; Sjoegren Syndrome/Scleroderma Autoantigen 1
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMAL NGAE VDDFSWEPPT EAETKVLQAR RERQDRISRL MGDYLLRGYR MLGETCADCG TILLQDKQRK IYCVACQELD SDVDKDNPAL NAQAALSQAR EHQLASASEL PLGSRPAPQP PVPRPEHCEG AAAGLKAAQG PPAPAVPPNT DVMACTQTAL LQKLTWASAE LGSSTSLETS IQLCGLIRAC AEALRSLQQL QH
Host
E Coli
Form/Format
SSSCA1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Molecular Weight
21,474 Da
OMIM
606044
3D Structure
ModBase 3D Structure for O60232

Other Notes

Small volumes of SSSCA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SSSCA1 purchase

MBS146463 is a recombinant protein targeting SSSCA1. Also known as Recombinant Human Sjogren Syndrome/Scleroderma Autoantigen 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SSSCA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Sjoegren syndrome/scleroderma autoantigen 1 isoform 1
NCBI Official Synonym Full Names
Sjogren syndrome/scleroderma autoantigen 1
NCBI Official Symbol
SSSCA1
NCBI Official Synonym Symbols
p27
UniProt Protein Name
Sjoegren syndrome/scleroderma autoantigen 1
UniProt Synonym Protein Names
Autoantigen p27
UniProt Gene Name
SSSCA1
UniProt Entry Name
SSA27_HUMAN
NCBI Protein Information
Sjoegren syndrome/scleroderma autoantigen 1; Sjogren's syndrome/scleroderma autoantigen 1; autoantigen p27; centromeric autoantigen (27kD)

NCBI Summary for SSSCA1

This antigen is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established. [provided by RefSeq, Jul 2008]

UniProt Comments for SSSCA1

SSSCA1: Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies.

Chromosomal Location of Human Ortholog: 11q13.1

Molecular Function: identical protein binding; protein binding

Biological Process: mitosis; cell division

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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