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Star-Related Lipid Transfer Domain Containing 5 (STARD5) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146494

Description: STARD5 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain topological domain containing 236 amino acids (1-213 a.a) and having a molecular mass of 26.2kDa. STARD5 is fused to a 23 amino acid His-tag at N-terminus… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
StAR-Related Lipid Transfer Domain Containing 5 (STARD5), Recombinant Protein
Full Product Name
Recombinant Human StAR-Related Lipid Transfer Domain Containing 5
Product Synonym Names
STARD5 Human; StAR-Related Lipid Transfer Domain Containing 5 Human Recombinant; StAR-Related Lipid Transfer (START) Domain Containing 5; START Domain-Containing Protein 5; StARD5
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMDP ALAA QMSEAVAEKM LQYRRDTAGW KICREGNGVS VSWRPSVEFP GNLYRGEGIV YGTLEEVWDC VKPAVGGLRV KWDENVTGFE IIQSITDTLC VSRTSTPSAA MKLISPRDFV DLVLVKRYED GTISSNATHV EHPLCPPKPG FVRGFNHPCG CFCEPLPGEP TKTNLVTFFH TDLSGYLPQN VVDSFFPRSM TRFYANLQKA VKQFHE
Host
E Coli
Form/Format
STARD5 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 0.1M NaCl, 1mM DTT and 20% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Molecular Weight
7,094 Da
OMIM
607050
3D Structure
ModBase 3D Structure for Q9NSY2

Other Notes

Small volumes of STARD5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STARD5 purchase

MBS146494 is a recombinant protein targeting STARD5. Also known as Recombinant Human StAR-Related Lipid Transfer Domain Containing 5. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for STARD5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
stAR-related lipid transfer protein 5
NCBI Official Synonym Full Names
StAR-related lipid transfer (START) domain containing 5
NCBI Official Symbol
STARD5
UniProt Protein Name
StAR-related lipid transfer protein 5
UniProt Synonym Protein Names
START domain-containing protein 5; StARD5
UniProt Gene Name
STARD5
UniProt Synonym Gene Names
StARD5
UniProt Entry Name
STAR5_HUMAN
NCBI Protein Information
stAR-related lipid transfer protein 5; START domain containing 5; START domain-containing protein 5

NCBI Summary for STARD5

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008]
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UniProt Comments for STARD5

STARD5: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q26

Cellular Component: cytosol

Molecular Function: bile acid binding

Biological Process: steroid metabolic process; C21-steroid hormone biosynthetic process; lipid transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with STARD5 recombinant protein

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