Human HBQ1 Recombinant Protein – Cat# MBS146497

Hemoglobin Theta 1 (HBQ1) Human Recombinant Protein

Name: HBQ1 Recombinant Protein; Hemoglobin Theta 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS146497
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146497

Description: HBQ1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 165 amino acids (1-142) and having a molecular mass of 17.9kDa.HBQ1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Hemoglobin Theta 1 (HBQ1), Recombinant Protein

Full Product Name

Recombinant Human Hemoglobin Theta 1

Product Gene Name

HBQ1 recombinant protein

Product Synonym Names

HBQ1 Human; Hemoglobin Theta 1 Human Recombinant; Hemoglobin Theta 1; Hemoglobin Theta-1 Chain; Hemoglobin Subunit Theta-1; Theta-1-globin

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMAL SAED RALVRALWKK LGSNVGVYTT EALERTFLAF PATKTYFSHL DLSPGSSQVR AHGQKVADAL SLAVERLDDL PHALSALSHL HACQLRVDPA SFQLLGHCLL VTLARHYPGD FSPALQASLD KFLSHVISAL VSEYR

Host

E Coli

Form/Format

The HBQ1 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol.
Sterile filtered colorless solution.

Purity/Purification

Greater than 90% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

15,508 Da

OMIM

142240

3D Structure

ModBase 3D Structure for P09105

Product Categories/Family for HBQ1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Hemoglobin

Other Notes

Small volumes of HBQ1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HBQ1 purchase

MBS146497 is a recombinant protein targeting HBQ1. Also known as Recombinant Human Hemoglobin Theta 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for HBQ1. It may not necessarily be applicable to this product.

NCBI GI #

4885395

NCBI GeneID

3049

NCBI Accession #

NP_005322.1

UniProt Primary Accession #

P09105

UniProt Secondary Accession #

Q13723; Q1W6G5

UniProt Related Accession #

P09105

GenBank Nucleotide #

NM_005331.4

NCBI Official Full Name

hemoglobin subunit theta-1

NCBI Official Synonym Full Names

hemoglobin, theta 1

NCBI Official Symbol

HBQ1

NCBI Official Synonym Symbols

HBQ

UniProt Protein Name

Hemoglobin subunit theta-1

UniProt Synonym Protein Names

Hemoglobin theta-1 chain; Theta-1-globin

Protein Family

Hemoglobin

UniProt Gene Name

HBQ1

UniProt Entry Name

HBAT_HUMAN

NCBI Protein Information

hemoglobin subunit theta-1; hemoglobin theta-1 chain; theta-1-globin

NCBI Summary for HBQ1

Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue. [provided by RefSeq, Jul 2008]

UniProt Comments for HBQ1

HBQ1: Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: hemoglobin complex

Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: oxygen transport

Research Articles on HBQ1

1. 2 new Spanish alpha-thalassemia mutations were found. In both mutations, both alpha genes were deleted, the gene theta; and the region HS40.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HBQ1 recombinant protein

Reference Product	PubMed Publications
HBB recombinant protein	>2 publications with HBQ1 and HBB
HBE1 recombinant protein	>2 publications with HBQ1 and HBE1
HBD recombinant protein	>2 publications with HBQ1 and HBD
HBA2 recombinant protein	>1 publications with HBQ1 and HBA2
HBZ recombinant protein	>1 publications with HBQ1 and HBZ
HBA1 recombinant protein	>1 publications with HBQ1 and HBA1
NGB recombinant protein	>1 publications with HBQ1 and NGB

Diseases associated with HBQ1 recombinant protein

Disease Name	Pubmed Publications
Anemia Antibodies	>1 publications with HBQ1 and Anemia