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Dynactin 2 (DCTN2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146501

MBS146501 is a recombinant protein targeting DCTN2. Also known as Recombinant Human Dynactin 2 (1-406 a.a.). More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dynactin 2 (DCTN2), Recombinant Protein
Full Product Name
Recombinant Human Dynactin 2 (1-406 a.a.)
Product Gene Name
DCTN2 recombinant protein
Product Synonym Names
DCTN2 (1-406)
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMAD PKYA DLPGIARNEP DVYETSDLPE DDQAEFDAFA QELEELTSTS VEHIIVNPNA AYDKFKDKRV GTKGLDFSDR IGKTKRTGYE SGEYEMLGEG LGVKETPQQK YQRLLHEVQE LTTEVEKIKT TVKESATEEK LTPVLLAKQL AALKQQLVAS HLEKLLGPDA AINLTDPDGA LAKRLLLQLE ATKNSKGGSG GKTTGTPPDS SLVTYELHSR PEQDKFSQAA KVAELEKRLT ELETAVRCDQ DAQNPLSAGL QGACLMETVE LLQAKVSALD LAVLDQVEAR LQSVLGKVNE IAKHKASVED ADTQSKVHQL YETIQRWSPI ASTLPELVQR LVTIKQLHEQ AMQFGQLLTH LDTTQQMIAN SLKDNTTLLT QVQTTMRENL ATVEGNFASI DERMKKLGK.
Molecular Weight
44,117 Da

Product Categories/Family for DCTN2 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of DCTN2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DCTN2. It may not necessarily be applicable to this product.

NCBI GI #
148692542
NCBI GeneID
69654
NCBI Accession #
EDL24489.1
UniProt Related Accession #
Q99KJ8
NCBI Official Full Name
dynactin 2
NCBI Official Synonym Full Names
dynactin 2
NCBI Official Symbol
Dctn2
NCBI Official Synonym Symbols
p50; RBP50; C87049; DCTN-50; GMP23-48K; 2310042E05Rik; C130077D06Rik
UniProt Protein Name
Dynactin subunit 2
UniProt Synonym Protein Names
50 kDa dynein-associated polypeptide; Dynactin complex 50 kDa subunit; DCTN-50; Growth cone membrane protein 23-48K; GMP23-48K; p50 dynamitin
Protein Family
Dynactin
UniProt Gene Name
Dctn2
UniProt Synonym Gene Names
DCTN-50; GMP23-48K
UniProt Entry Name
DCTN2_MOUSE
NCBI Protein Information
dynactin subunit 2; 50 kDa dynein-associated polypeptide; dynactin complex 50 kDa subunit; growth cone membrane protein 23-48K; p50 dynamitin

UniProt Comments for DCTN2

dynactin 2: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development. Belongs to the dynactin subunit 2 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding; Motor; Cytoskeletal; Motility/polarity/chemotaxis; Cell cycle regulation

Cellular Component: kinetochore; dynein complex; microtubule; centrosome; dynactin complex; growth cone; cytoskeleton; membrane; cell; cytoplasm; vesicle

Molecular Function: protein binding; spectrin binding; motor activity

Biological Process: mitosis; cell proliferation; mitotic spindle organization and biogenesis; melanosome transport; microtubule-based process
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Research Articles on DCTN2

1. Altered levels of Cep135 and p50 by RNAi and protein overexpression caused the release of endogenous partner molecules from centrosomes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DCTN2 recombinant protein

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies  Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Centrosome Maturation Pathway antibodies  Centrosome Maturation Pathway Diagram
 G2/M Transition Pathway antibodies  G2/M Transition Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram

Diseases associated with DCTN2 recombinant protein

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >1 publications with DCTN2 and Adenocarcinoma
 Breast Neoplasms Antibodies  >1 publications with DCTN2 and Breast Neoplasms
 Nervous System Diseases Antibodies  >1 publications with DCTN2 and Nervous System Diseases

Organs/Tissues associated with DCTN2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with DCTN2 and Brain
 Bone Antibodies  >1 publications with DCTN2 and Bone
 Liver Antibodies  >1 publications with DCTN2 and Liver
 Spinal Cord Antibodies  >1 publications with DCTN2 and Spinal Cord
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