Human GCSAM Recombinant Protein – Cat# MBS146565

Germinal Center-Associated (GCSAM) Human Recombinant Protein

Name: GCSAM Recombinant Protein; Germinal Center-Associated; Human; MyBioSource
Brand: MyBioSource
SKU: MBS146565
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146565

Description: GCSAM Human Recombinant produced in E Coli is a single polypeptide chain containing 201 amino acids (1-178) and having a molecular mass of 23 kDa. GCSAM is fused to 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Germinal Center-Associated (GCSAM), Recombinant Protein

Full Product Name

Recombinant Human Germinal Center-Associated, Signaling and Motility

Product Gene Name

GCSAM recombinant protein

Product Synonym Names

GCSAM Human; Germinal Center-Associated, Signaling and Motility Human Recombinant; GCAT2; HGAL; Germinal center-associated signaling and motility protein; Germinal center B-cell-expressed transcript 2 protein; Germinal center-associated lymphoma protein; GAL; GCET2

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMGN SLLR ENRRQQNTQE MPWNVRMQSP KQRTSRCWDH HIAEGCFCLP WKKILIFEKR QDSQNENERM SSTPIQDNVD QTYSEELCYT LINHRVLCTR PSGNSAEEYY ENVPCKAERP RESLGGTETE YSLLHMPSTD PRHARSPEDE YELLMPHRIS SHFLQQPRPL MAPSETQFSH L

Host

E Coli

Form/Format

The GCSAM solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 1mM DTT.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 85% as determined by SDS-PAGE.

Molecular Weight

19,206 Da

OMIM

607792

3D Structure

ModBase 3D Structure for Q8N6F7

Product Categories/Family for GCSAM recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of GCSAM recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GCSAM purchase

MBS146565 is a recombinant protein targeting GCSAM. Also known as Recombinant Human Germinal Center-Associated, Signaling and Motility. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GCSAM. It may not necessarily be applicable to this product.

NCBI GI #

298231242

NCBI GeneID

257144

NCBI Accession #

NP_001177188.1

UniProt Primary Accession #

Q8N6F7

UniProt Secondary Accession #

C9JD17; C9JUG6

UniProt Related Accession #

Q8N6F7

GenBank Nucleotide #

NM_001190259.1

NCBI Official Full Name

germinal center-associated signaling and motility protein isoform 3

NCBI Official Synonym Full Names

germinal center-associated, signaling and motility

NCBI Official Symbol

GCSAM

NCBI Official Synonym Symbols

HGAL; GCAT2; GCET2

UniProt Protein Name

Germinal center-associated signaling and motility protein

UniProt Synonym Protein Names

Germinal center B-cell-expressed transcript 2 protein; Germinal center-associated lymphoma protein; hGAL

Protein Family

Germinal center-associated signaling and motility protein

UniProt Gene Name

GCSAM

UniProt Synonym Gene Names

GAL; GCET2; hGAL

UniProt Entry Name

GCSAM_HUMAN

NCBI Protein Information

germinal center-associated signaling and motility protein; germinal center B-cell-expressed transcript 2 protein; germinal center expressed transcript 2; germinal center-associated lymphoma protein; human germinal center-associated lymphoma

NCBI Summary for GCSAM

This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

UniProt Comments for GCSAM

GCET2: a protein expressed in normal germinal center B cells, immature B and T cells. Induced by IL4. Its expression strongly predicts survival in diffuse large B-cell lymphoma.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: cytoplasm; plasma membrane

Molecular Function: protein binding; actin binding; protein kinase binding; myosin II binding

Biological Process: regulation of B cell receptor signaling pathway

Research Articles on GCSAM

1. HGAL and LMO2 may be useful adjuncts in the identification of follicular lymphoma of the nongastric gastrointestinal tract.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.