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Retinoic Acid-Induced Protein 1 (RAI1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1465761

This gene is located within the Smith-Magenis syndrome region on chromosome 17. It is highly similar to its mouse counterpart and is expressed at high levels mainly in neuronal tissues. This protein includes a polymorphic polyglutamine tract in the N-terminal… More details

$760 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Retinoic acid-induced protein 1 (Rai1), Recombinant Protein
Full Product Name
Recombinant Mouse Retinoic acid-induced protein 1 (Rai1) , partial
Product Gene Name
Rai1 recombinant protein
Product Synonym Gene Name
Rai1
Sequence
RLQSCYCCDG QGDGGEEVAQ ADKSRKHECS KEAPTEPGGD TQEHWVHEAC AVWTSGVYLV AGKLFGLQEA MKVAVDMPCT SCHEPGATIS CSYKGCIHTY HYPCANDTGC TFIEENFTLK CPKHKRLPL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
196,084 Da
Sequence Positions
1761-1889aa; Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q61818
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Rai1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rai1 purchase

MBS1465761 is a recombinant protein targeting Rai1. Also known as Recombinant Mouse Retinoic acid-induced protein 1 (Rai1) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Rai1. It may not necessarily be applicable to this product.

NCBI GI #
83649745
NCBI GeneID
19377
NCBI Accession #
NP_001032853.1
UniProt Primary Accession #
Q61818
UniProt Secondary Accession #
Q6ZPH7; Q8CEV1; B1AU87
UniProt Related Accession #
Q61818
GenBank Nucleotide #
NM_001037764.1
NCBI Official Full Name
retinoic acid-induced protein 1
NCBI Official Synonym Full Names
retinoic acid induced 1
NCBI Official Symbol
Rai1
NCBI Official Synonym Symbols
Gt1
UniProt Protein Name
Retinoic acid-induced protein 1
Protein Family
Decapping nuclease
UniProt Gene Name
Rai1
UniProt Synonym Gene Names
Kiaa1820
NCBI Protein Information
retinoic acid-induced protein 1

UniProt Comments for Rai1

Transcriptional regulator of the circadian clock components: CLOCK, ARNTL/BMAL1, ARNTL2/BMAL2, PER1/3, CRY1/2, NR1D1/2 and RORA/C. Positively regulates the transcriptional activity of CLOCK a core component of the circadian clock. Regulates transcription through chromatin remodeling by interacting with other proteins in chromatin as well as proteins in the basic transcriptional machinery. May be important for embryonic and postnatal development. May be involved in neuronal differentiation.
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Research Articles on Rai1

1. Rai1 preferentially occupies DNA regions near active promoters and promotes the expression of a group of genes involved in circuit assembly and neuronal communication. Behavioral analyses demonstrated that pan-neural loss of Rai1 causes deficits in motor function, learning, and food intake.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Rai1 recombinant protein

 Disease Name  Pubmed Publications
 Smith-Magenis Syndrome Antibodies  >47 publications with Rai1 and Smith-Magenis Syndrome
 Congenital Abnormalities Antibodies  >41 publications with Rai1 and Congenital Abnormalities
 Intellectual Disability Antibodies  >25 publications with Rai1 and Intellectual Disability
 Neurobehavioral Manifestations Antibodies  >24 publications with Rai1 and Neurobehavioral Manifestations
 Craniofacial Abnormalities Antibodies  >18 publications with Rai1 and Craniofacial Abnormalities
 Obesity Antibodies  >10 publications with Rai1 and Obesity
 Potocki-Lupski syndrome Antibodies  >9 publications with Rai1 and Potocki-Lupski syndrome
 Central Nervous System Diseases Antibodies  >7 publications with Rai1 and Central Nervous System Diseases
 Child Development Disorders, Pervasive Antibodies  >5 publications with Rai1 and Child Development Disorders, Pervasive
 Growth Disorders Antibodies  >4 publications with Rai1 and Growth Disorders

Organs/Tissues associated with Rai1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with Rai1 and Brain
 Heart Antibodies  >5 publications with Rai1 and Heart
 Muscle Antibodies  >2 publications with Rai1 and Muscle
 Skin Antibodies  >2 publications with Rai1 and Skin
 Kidney Antibodies  >2 publications with Rai1 and Kidney
 Liver Antibodies  >1 publications with Rai1 and Liver
 Embryonic Tissue Antibodies  >1 publications with Rai1 and Embryonic Tissue
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