Mouse HMGCS1 Recombinant Protein – Cat# MBS1465861

Hydroxymethylglutaryl-Coa Synthase (HMGCS1) Mouse Recombinant Protein

Name: HMGCS1 Recombinant Protein; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS1465861
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1465861

This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. More details

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Hydroxymethylglutaryl-CoA synthase (Hmgcs1), Recombinant Protein

Full Product Name

Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, cytoplasmic

Product Gene Name

Hmgcs1 recombinant protein

Product Synonym Names

3-hydroxy-3-methylglutaryl coenzyme A synthase

Sequence

MPGSLPLNAE ACWPKDVGIV ALEIYFPSQY VDQAELEKYD GVDAGKYTIG LGQARMGFCT DREDINSLCL TVVQKLMERH SLSYDCIGRL EVGTETIIDK SKSVKSNLMQ LFEESGNTDI EGIDTTNACY GGTAAVFNAV NWVESSSWDG RYALVVAGDI AIYATGNARP TGGVGAVALL IGPNAPLIFD RGLRGTHMQH AYDFYKPDML SEYPVVDGKL SIQCYLSALD RCYSVYRKKI RAQWQKEGKD KDFTLNDFGF MIFHSPYCKL VQKSLARMFL NDFLNDQNRD KNSIYSGLEA FGDVKLEDTY FDRDVEKAFM KASSELFNQK TKASLLVSNQ NGNMYTSSVY GSLASVLAQY SPQQLAGKRV GVFSYGSGLA ATLYSLKVTQ DATPGSALDK ITASLCDLKS RLDSRTCVAP DVFAENMKLR EDTHHLANYI PQCSIDSLFE GTWYLVRVDE KHRRTYARRP FTNDHSLDEG MGLVHSNTAT EHIPSPAKKV PRLPATSAES ESAVISNGEH

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Molecular Weight

59.6 kDa

Sequence Positions

1-520aa; Full Length

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q8JZK9

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Hmgcs1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Hmgcs1 purchase

MBS1465861 is a recombinant protein targeting Hmgcs1. Also known as Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, cytoplasmic. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Hmgcs1. It may not necessarily be applicable to this product.

NCBI GI #

612339316

NCBI GeneID

208715

NCBI Accession #

NP_001278368.1

UniProt Primary Accession #

Q8JZK9

UniProt Secondary Accession #

Q3UXI4

UniProt Related Accession #

Q8JZK9

GenBank Nucleotide #

NM_001291439.1

NCBI Official Full Name

hydroxymethylglutaryl-CoA synthase, cytoplasmic

NCBI Official Synonym Full Names

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1

NCBI Official Symbol

Hmgcs1

NCBI Official Synonym Symbols

B130032C06Rik

UniProt Protein Name

Hydroxymethylglutaryl-CoA synthase, cytoplasmic

UniProt Synonym Protein Names

3-hydroxy-3-methylglutaryl coenzyme A synthase

Protein Family

Hydroxymethylglutaryl-CoA synthase

UniProt Gene Name

Hmgcs1

UniProt Synonym Gene Names

HMG-CoA synthase

UniProt Entry Name

HMCS1_MOUSE

NCBI Protein Information

hydroxymethylglutaryl-CoA synthase, cytoplasmic

UniProt Comments for Hmgcs1

HMGCS1: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Belongs to the HMG-CoA synthase family.

Protein type: Carbohydrate Metabolism - butanoate; Lipid Metabolism - synthesis and degradation of ketone bodies; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 2.3.3.10; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Transferase

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus; plasma membrane

Molecular Function: catalytic activity; drug binding; hydroxymethylglutaryl-CoA synthase activity; isomerase activity; organic acid binding; protein homodimerization activity; transferase activity

Biological Process: cholesterol biosynthetic process; cholesterol metabolic process; isoprenoid biosynthetic process; lipid metabolic process; metabolic process; response to organic nitrogen; steroid biosynthetic process; steroid metabolic process; sterol biosynthetic process

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Hmgcs1 recombinant protein

Reference Product	PubMed Publications
Hmgcr recombinant protein	>24 publications with Hmgcs1 and Hmgcr
Sqle recombinant protein	>8 publications with Hmgcs1 and Sqle
Idi1 recombinant protein	>6 publications with Hmgcs1 and Idi1
Srebf2 recombinant protein	>4 publications with Hmgcs1 and Srebf2
Acat2 recombinant protein	>3 publications with Hmgcs1 and Acat2
Acaa1a recombinant protein	>1 publications with Hmgcs1 and Acaa1a
Mvd recombinant protein	>1 publications with Hmgcs1 and Mvd

Pathways associated with Hmgcs1 recombinant protein

Products by Pathway	Pathway Diagram
Butanoate Metabolism Pathway antibodies	Butanoate Metabolism Pathway Diagram
Butanoate Metabolism Pathway antibodies	Butanoate Metabolism Pathway Diagram
C5 Isoprenoid Biosynthesis, Mevalonate Pathway antibodies	C5 Isoprenoid Biosynthesis, Mevalonate Pathway Diagram
C5 Isoprenoid Biosynthesis, Mevalonate Pathway antibodies	C5 Isoprenoid Biosynthesis, Mevalonate Pathway Diagram
Cholesterol Biosynthesis Pathway antibodies	Cholesterol Biosynthesis Pathway Diagram
Cholesterol Biosynthesis Pathway antibodies	Cholesterol Biosynthesis Pathway Diagram
Endochondral Ossification Pathway antibodies	Endochondral Ossification Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram

Diseases associated with Hmgcs1 recombinant protein

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>8 publications with Hmgcs1 and Fatty Liver
Liver Diseases Antibodies	>8 publications with Hmgcs1 and Liver Diseases
Inflammation Antibodies	>5 publications with Hmgcs1 and Inflammation
Carcinoma, Hepatocellular Antibodies	>4 publications with Hmgcs1 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>4 publications with Hmgcs1 and Liver Neoplasms
Hepatitis Antibodies	>4 publications with Hmgcs1 and Hepatitis
Cardiovascular Diseases Antibodies	>4 publications with Hmgcs1 and Cardiovascular Diseases
Weight Loss Antibodies	>3 publications with Hmgcs1 and Weight Loss
Mental Disorders Antibodies	>3 publications with Hmgcs1 and Mental Disorders
Disease Models, Animal Antibodies	>3 publications with Hmgcs1 and Disease Models, Animal

Organs/Tissues associated with Hmgcs1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>23 publications with Hmgcs1 and Liver
Blood Antibodies	>13 publications with Hmgcs1 and Blood
Lung Antibodies	>3 publications with Hmgcs1 and Lung
Ovary Antibodies	>3 publications with Hmgcs1 and Ovary
Brain Antibodies	>3 publications with Hmgcs1 and Brain
Bone Antibodies	>3 publications with Hmgcs1 and Bone
Spinal Cord Antibodies	>2 publications with Hmgcs1 and Spinal Cord
Connective Tissue Antibodies	>2 publications with Hmgcs1 and Connective Tissue
Heart Antibodies	>2 publications with Hmgcs1 and Heart
Muscle Antibodies	>1 publications with Hmgcs1 and Muscle