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Endocrine Gland Vascular Endothelial Growth Factor (mEG VEGF) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146611

Description: EG-VEGF Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 86 amino acids and having a molecular mass of 9.6kDa.Introduction: Endocrine gland-derived vascular endothelial growth factor (EG-VEGF)… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Endocrine Gland Vascular Endothelial Growth Factor (mEG VEGF), Recombinant Protein
Full Product Name
Recombinant Mouse Endocrine Gland Vascular Endothelial Growth Factor
Product Gene Name
mEG VEGF recombinant protein
Product Synonym Names
EG VEGF Mouse; Endocrine Gland Vascular Endothelial Growth Factor Mouse Recombinant; PK1; Prokineticin 1; EG-VEGF; Prok1; Endocrine-gland-derived vascular endothelial growth factor
Sequence
AVITGACERD IQCGAGTCCA ISLWLRGLRL CTPLGREGEE CHPGSHKIPF LRKRQHHTCP CSPSLLCSRF PDGRYRCFRD LKNANF
Host
E Coli
Form/Format
Lyophilized from a 0.2 um filtered concentrated solution in PBS pH7.4 and 3% Trehalose.
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity/Purification
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Preparation and Storage
Lyophilized EG-VEGF Human Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution EG-VEGF should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.
Molecular Weight
10,078 Da
3D Structure
ModBase 3D Structure for Q14A28
Solubility
It is recommended to reconstitute the lyophilized Endocrine Gland Vascular Endothelial Growth Factor in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Product Categories/Family for mEG VEGF recombinant protein

Cytokines and Growth Factors; Growth Factors; VEGF

Other Notes

Small volumes of mEG VEGF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for mEG VEGF purchase

MBS146611 is a recombinant protein targeting mEG VEGF. Also known as Recombinant Mouse Endocrine Gland Vascular Endothelial Growth Factor. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for mEG VEGF. It may not necessarily be applicable to this product.

NCBI GI #
117676357
NCBI GeneID
246691
NCBI Accession #
NP_001037847.1
UniProt Primary Accession #
Q14A28
UniProt Secondary Accession #
Q0P609; Q8K457
UniProt Related Accession #
Q14A28
GenBank Nucleotide #
NM_001044382.1
NCBI Official Full Name
prokineticin-1
NCBI Official Synonym Full Names
prokineticin 1
NCBI Official Symbol
Prok1
NCBI Official Synonym Symbols
EG-VEGF
UniProt Protein Name
Prokineticin-1
UniProt Synonym Protein Names
Endocrine-gland-derived vascular endothelial growth factor
UniProt Gene Name
Prok1
UniProt Entry Name
PROK1_MOUSE
NCBI Protein Information
prokineticin-1; EG-VEGF; endocrine-gland-derived vascular endothelial growth factor; prok1

UniProt Comments for mEG VEGF

PROK1: Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. Belongs to the AVIT (prokineticin) family.

Protein type: Cell cycle regulation; Secreted; Secreted, signal peptide

Cellular Component: extracellular region

Molecular Function: G-protein-coupled receptor binding; growth factor activity

Biological Process: circadian rhythm; activation of MAPK activity; positive regulation of cell division; positive regulation of cell proliferation; angiogenesis; regulation of angiogenesis
Show more

Research Articles on mEG VEGF

1. Prokineticin-1 (Prok-1) works coordinately with glial cell line-derived neurotrophic factor (GDNF) to mediate proliferation and differentiation of enteric neural crest cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with mEG VEGF recombinant protein

 Reference Product  PubMed Publications
 Prokr1 recombinant protein  >28 publications with mEG VEGF and Prokr1
 Prok2 recombinant protein  >23 publications with mEG VEGF and Prok2
 Prokr2 recombinant protein  >17 publications with mEG VEGF and Prokr2

Pathways associated with mEG VEGF recombinant protein

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with mEG VEGF recombinant protein

 Disease Name  Pubmed Publications
 Premature Birth Antibodies  >3 publications with mEG VEGF and Premature Birth
 Hyperplasia Antibodies  >2 publications with mEG VEGF and Hyperplasia
 Inflammation Antibodies  >2 publications with mEG VEGF and Inflammation
 Nervous System Diseases Antibodies  >1 publications with mEG VEGF and Nervous System Diseases
 Pain Antibodies  >1 publications with mEG VEGF and Pain

Organs/Tissues associated with mEG VEGF recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >2 publications with mEG VEGF and Kidney
 Liver Antibodies  >2 publications with mEG VEGF and Liver
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