Human CAMLG Recombinant Protein – Cat# MBS146626

Calcium Modulating Ligand (CAMLG) Human Recombinant Protein

Name: CAMLG Recombinant Protein; Calcium Modulating Ligand; Human; MyBioSource
Brand: MyBioSource
SKU: MBS146626
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146626

Description: CAMLG Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 212 amino acids (1-189) and having a molecular mass of 23.2kDa.CAMLG is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Calcium Modulating Ligand (CAMLG), Recombinant Protein

Full Product Name

Recombinant Human Calcium Modulating Ligand

Product Gene Name

CAMLG recombinant protein

Product Synonym Names

CAMLG Human; Calcium Modulating Ligand Human Recombinant; Calcium Modulating Ligand; Calcium-Modulating Cyclophilin Ligand; Calcium-Signal Modulating Cyclophilin Ligand; Cyclophilin B-Binding Protein; CAML

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMES MAVA TDGGERPGVP AGSGLSASQR RAELRRRKLL MNSEQRINRI MGFHRPGSGA EEESQTKSKQ QDSDKLNSLS VPSVSKRVVL GDSVSTGTTD QQGGVAEVKG TQLGDKLDSF IKPPECSSDV NLELRQRNRG DLTADSVQRG SRHGLEQYLS RFEEAMKLRK QLISEKPSQE DGNTTEEFDS FR

Host

E Coli

Form/Format

The CAMLG solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol.
Sterile filtered colorless solution.

Purity/Purification

Greater than 90% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

32,953 Da

OMIM

601118

3D Structure

ModBase 3D Structure for P49069

Product Categories/Family for CAMLG recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Calcium Binding Protein

Other Notes

Small volumes of CAMLG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CAMLG purchase

MBS146626 is a recombinant protein targeting CAMLG. Also known as Recombinant Human Calcium Modulating Ligand. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CAMLG. It may not necessarily be applicable to this product.

NCBI GI #

4502559

NCBI GeneID

819

NCBI Accession #

NP_001736.1

UniProt Primary Accession #

P49069

UniProt Secondary Accession #

A1L3Y3

UniProt Related Accession #

P49069

GenBank Nucleotide #

NM_001745.3

NCBI Official Full Name

calcium signal-modulating cyclophilin ligand

NCBI Official Synonym Full Names

calcium modulating ligand

NCBI Official Symbol

CAMLG

NCBI Official Synonym Symbols

CAML

UniProt Protein Name

Calcium signal-modulating cyclophilin ligand

Protein Family

Calcium signal-modulating cyclophilin ligand

UniProt Gene Name

CAMLG

UniProt Synonym Gene Names

CAML; CAML

UniProt Entry Name

CAMLG_HUMAN

NCBI Protein Information

calcium signal-modulating cyclophilin ligand; calcium-modulating cyclophilin ligand; calcium-signal modulating cyclophilin ligand; cyclophilin B-binding protein

NCBI Summary for CAMLG

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]

UniProt Comments for CAMLG

CAMLG: Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 5q23

Cellular Component: membrane; endoplasmic reticulum; integral to membrane

Molecular Function: protein binding; cell adhesion molecule binding

Biological Process: receptor recycling; epidermal growth factor receptor signaling pathway; viral reproduction; defense response; signal transduction

Research Articles on CAMLG

1. Found that the calcium-modulating cyclophilin ligand (CAMLG), which is involved in Ca(2+) signaling, was the major host cell PilA binding protein.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CAMLG recombinant protein

Reference Product	PubMed Publications
BST2 recombinant protein	>3 publications with CAMLG and BST2
TMUB1 recombinant protein	>2 publications with CAMLG and TMUB1
TNFRSF13B recombinant protein	>2 publications with CAMLG and TNFRSF13B
PKHD1 recombinant protein	>1 publications with CAMLG and PKHD1
EGFR recombinant protein	>1 publications with CAMLG and EGFR
PRLR recombinant protein	>1 publications with CAMLG and PRLR
RNF122 recombinant protein	>1 publications with CAMLG and RNF122

Diseases associated with CAMLG recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>2 publications with CAMLG and Necrosis
Carcinoma Antibodies	>1 publications with CAMLG and Carcinoma
Kidney Diseases Antibodies	>1 publications with CAMLG and Kidney Diseases

Organs/Tissues associated with CAMLG recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>2 publications with CAMLG and Liver
Bone Antibodies	>1 publications with CAMLG and Bone
Thyroid Antibodies	>1 publications with CAMLG and Thyroid
Vascular Antibodies	>1 publications with CAMLG and Vascular
Prostate Antibodies	>1 publications with CAMLG and Prostate
Kidney Antibodies	>1 publications with CAMLG and Kidney
Thymus Antibodies	>1 publications with CAMLG and Thymus
Uncharacterized Tissue Antibodies	>1 publications with CAMLG and Uncharacterized Tissue
Brain Antibodies	>1 publications with CAMLG and Brain