Human TRIP10 Recombinant Protein – Cat# MBS146628

Thyroid Hormone Receptor Interactor 10 (TRIP10) Human Recombinant Protein

Name: TRIP10 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS146628
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146628

Description: TRIP10 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 309 amino acids (260-545) and having a molecular mass of 34.6 kDa.TRIP10 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Thyroid Hormone Receptor Interactor 10 (TRIP10), Recombinant Protein

Full Product Name

Recombinant Human Thyroid Hormone Receptor Interactor 10

Product Gene Name

TRIP10 recombinant protein

Product Synonym Names

TRIP10 Human; Thyroid Hormone Receptor Interactor 10 Human Recombinant; Cdc42-interacting protein 4; Protein Felic; Salt tolerant protein; hSTP; Thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10; TRIP10; CIP4; STOT; STP; HSTP

Sequence

MGSSHHH HHH SSGLVPRGSH MGSDPK NDSH VLIELHKSGF ARPGDVEFED FSQPMNRAPS DSSLGTPSDG RPELRGPGRS RTKRWPFGKK NKTVVTEDFS HLPPEQQRKR LQQQLEERSR ELQKEVDQRE ALKKMKDVYE KTPQMGDPAS LEPQIAETLS NIERLKLEVQ KYEAWLAEAE SRVLSNRGDS LSRHARPPDP PASAPPDSSS NSASQDTKES SEEPPSEESQ DTPIYTEFDE DFEEEPTSPI GHCVAIYHFE GSSEGTISMA EGEDLSLMEE DKGDGWTRVR RKEGGEGYVP TSYLRVTLN.

Host

E Coli

Form/Format

The TRIP10 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol, 1mM DTT.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

39,583 Da

OMIM

604504

3D Structure

ModBase 3D Structure for Q15642

Product Categories/Family for TRIP10 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of TRIP10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRIP10 purchase

MBS146628 is a recombinant protein targeting TRIP10. Also known as Recombinant Human Thyroid Hormone Receptor Interactor 10. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIP10. It may not necessarily be applicable to this product.

NCBI GI #

572874682

NCBI GeneID

9322

NCBI Accession #

NP_001275891.1

UniProt Primary Accession #

Q15642

UniProt Secondary Accession #

O15184; Q53G22; Q5TZN1; Q6FI24; Q8NFL1; Q8TCY1; Q8TDX3; Q96RJ1; B2R8A6; B7WP22; D6W645

UniProt Related Accession #

Q15642

GenBank Nucleotide #

NM_001288962.1

NCBI Official Full Name

cdc42-interacting protein 4 isoform 1

NCBI Official Synonym Full Names

thyroid hormone receptor interactor 10

NCBI Official Symbol

TRIP10

NCBI Official Synonym Symbols

STP; CIP4; HSTP; STOT; TRIP-10

UniProt Protein Name

Cdc42-interacting protein 4

UniProt Synonym Protein Names

Protein Felic; Salt tolerant protein; hSTP; Thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10

Protein Family

Cdc42-interacting protein

UniProt Gene Name

TRIP10

UniProt Synonym Gene Names

CIP4; STOT; STP; hSTP; TR-interacting protein 10; TRIP-10

UniProt Entry Name

CIP4_HUMAN

NCBI Protein Information

cdc42-interacting protein 4; TR-interacting protein 10; protein Felic; salt tolerant protein; salt tolerator; thyroid receptor-interacting protein 10

UniProt Comments for TRIP10

TRIP10: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N- WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. Belongs to the FNBP1 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; Golgi apparatus; cytoskeleton; cell projection; intracellular membrane-bound organelle; lysosome; perinuclear region of cytoplasm; cytoplasm; cell cortex; cytosol; phagocytic cup

Molecular Function: identical protein binding; protein binding; lipid binding

Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; cell communication; endocytosis; signal transduction; actin cytoskeleton organization and biogenesis

Research Articles on TRIP10

1. CIP4 controls cell-cell cohesion and is required for the acquisition of an invasive phenotype in breast tumors

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TRIP10 recombinant protein

Products by Pathway	Pathway Diagram
Insulin Pathway antibodies	Insulin Pathway Diagram
Insulin Signaling Pathway antibodies	Insulin Signaling Pathway Diagram
Insulin Signaling Pathway antibodies	Insulin Signaling Pathway Diagram
Insulin-mediated Glucose Transport Pathway antibodies	Insulin-mediated Glucose Transport Pathway Diagram
Rho GTPase Cycle Pathway antibodies	Rho GTPase Cycle Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By Rho GTPases Pathway antibodies	Signaling By Rho GTPases Pathway Diagram

Diseases associated with TRIP10 recombinant protein

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>3 publications with TRIP10 and Immune System Diseases
Hypertension Antibodies	>3 publications with TRIP10 and Hypertension
Nervous System Diseases Antibodies	>2 publications with TRIP10 and Nervous System Diseases
Brain Diseases Antibodies	>2 publications with TRIP10 and Brain Diseases
Liver Neoplasms Antibodies	>2 publications with TRIP10 and Liver Neoplasms
Lung Diseases Antibodies	>1 publications with TRIP10 and Lung Diseases
Cognition Disorders Antibodies	>1 publications with TRIP10 and Cognition Disorders
Blood Coagulation Disorders Antibodies	>1 publications with TRIP10 and Blood Coagulation Disorders
Fibrosis Antibodies	>1 publications with TRIP10 and Fibrosis
Liver Diseases Antibodies	>1 publications with TRIP10 and Liver Diseases

Organs/Tissues associated with TRIP10 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>6 publications with TRIP10 and Blood
Thyroid Antibodies	>6 publications with TRIP10 and Thyroid
Brain Antibodies	>5 publications with TRIP10 and Brain
Muscle Antibodies	>5 publications with TRIP10 and Muscle
Kidney Antibodies	>4 publications with TRIP10 and Kidney
Nerve Antibodies	>3 publications with TRIP10 and Nerve
Heart Antibodies	>2 publications with TRIP10 and Heart
Liver Antibodies	>2 publications with TRIP10 and Liver
Lung Antibodies	>2 publications with TRIP10 and Lung
Skin Antibodies	>1 publications with TRIP10 and Skin