EGF Like Domain Multiple 6 (EGFL6) Human Recombinant Protein

Description: EGF Like Domain Multiple 6 Human Recombinant produced in HEK cells is a polypeptide chain (Asn22-Arg363) containing a total of 348 amino acids (including a 6xHis tag at C-terminus) and having a predicted molecular mass of 40kDa. The EGFL6 is purified by proprietary chromatographic techniques.
Introduction: Epidermal Growth Factor­like Domain Multiple 6 (EGFL6) belongs to the EGF repeat superfamily of proteins, whose members are involved in the regulation of cell cycle, proliferation, and developmental processes. EGFL6 gene product contains a signal peptide, suggesting that EGFL6 is secreted; an EGF repeat region consisting of four complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is assumed to have an adhesive function. Within shared regions, human EGFL6 shares 75% and 78% amino acid sequence identity with the mouse and rat orthologs, respectively. EGFL6 is expressed in various fetal tissues during early development such as the lung, heart, liver, spleen, cochlea and the placenta, as well as meningioma tumors.

Small volumes of EGFL6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS146746 is a recombinant protein targeting EGFL6. Also known as Recombinant Human EGF Like Domain Multiple 6. Host: HEK (Human embryonic kidney cells).