Human CPA4 Recombinant Protein – Cat# MBS146790

Carboxypeptidase A4 (CPA4) Human Recombinant Protein

Name: CPA4 Recombinant Protein; Carboxypeptidase A4; Human; MyBioSource
Brand: MyBioSource
SKU: MBS146790
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146790

Description: CPA4 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 413 amino acids (17-421a.a.) and having a molecular mass of 46.6kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). CPA4 is… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Carboxypeptidase A4 (CPA4), Recombinant Protein

Full Product Name

Recombinant Human Carboxypeptidase A4

Product Gene Name

CPA4 recombinant protein

Product Synonym Names

CPA4 Human; Carboxypeptidase A4; Carboxypeptidase A3; CPA3; EC 3.4.17.1; EC 3.4.17.-; EC 3.4.17; Carboxypeptidase A4; Carboxypeptidase A3; Carboxypeptidase A4 Human Recombinant

Sequence

GQEKFFGDQV LRINVRNGDE ISKLSQLVNS NNLKLNFWKS PSSFNRPVDV LVPSVSLQAF KSFLRSQGLE YAVTIEDLQA LLDNEDDEMQ HNEGQERSSN NFNYGAYHSL EAIYHEMDNI AADFPDLARR VKIGHSFENR PMYVLKFSTG KGVRRPAVWL NAGIHSREWI SQATAIWTAR KIVSDYQRDP AITSILEKMD IFLLPVANPD GYVYTQTQNR LWRKTRSRNP GSSCIGADPN RNWNASFAGK GASDNPCSEV YHGPHANSEV EVKSVVDFIQ KHGNFKGFID LHSYSQLLMY PYGYSVKKAP DAEELDKVAR LAAKALASVS GTEYQVGPTC TTVYPASGSS IDWAYDNGIK FAFTFELRDT GTYGFLLPAN QIIPTAEETW LGLKTIMEHV RDNLYLE HHH HHH.

Host

Sf9, Baculovirus cells

Form/Format

Sterile filtered colorless solution.
CPA4 protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Molecular Weight

43,570 Da

OMIM

AF095719 mRNA

3D Structure

ModBase 3D Structure for Q9UI42

Product Categories/Family for CPA4 recombinant protein

Enzymes

Other Notes

Small volumes of CPA4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CPA4 purchase

MBS146790 is a recombinant protein targeting CPA4. Also known as Recombinant Human Carboxypeptidase A4. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for CPA4. It may not necessarily be applicable to this product.

NCBI GI #

254540196

NCBI GeneID

51200

NCBI Accession #

NP_001156918.1

UniProt Primary Accession #

Q9UI42

UniProt Secondary Accession #

Q86UY9; B7Z576

UniProt Related Accession #

Q9UI42

GenBank Nucleotide #

NM_001163446.1

NCBI Official Full Name

carboxypeptidase A4 isoform 2

NCBI Official Synonym Full Names

carboxypeptidase A4

NCBI Official Symbol

CPA4

NCBI Official Synonym Symbols

CPA3

UniProt Protein Name

Carboxypeptidase A4

UniProt Synonym Protein Names

Carboxypeptidase A3

Protein Family

Carboxypeptidase

UniProt Gene Name

CPA4

UniProt Synonym Gene Names

CPA3

NCBI Protein Information

carboxypeptidase A4

NCBI Summary for CPA4

This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008]

UniProt Comments for CPA4

CPA4: Metalloprotease that could be involved in the histone hyperacetylation pathway. Belongs to the peptidase M14 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.17.-; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q32.2

Cellular Component: extracellular space

Molecular Function: metallocarboxypeptidase activity

Research Articles on CPA4

1. The crystal structure of the human CPA4 carboxypeptidase in complex with SmCI, a peptide protease inhibitor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with CPA4 recombinant protein

Disease Name	Pubmed Publications
Intestinal Neoplasms Antibodies	>1 publications with CPA4 and Intestinal Neoplasms
Liver Neoplasms Antibodies	>1 publications with CPA4 and Liver Neoplasms
Lung Neoplasms Antibodies	>1 publications with CPA4 and Lung Neoplasms
Breast Neoplasms Antibodies	>1 publications with CPA4 and Breast Neoplasms
Hyperplasia Antibodies	>1 publications with CPA4 and Hyperplasia

Organs/Tissues associated with CPA4 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>5 publications with CPA4 and Brain
Lung Antibodies	>3 publications with CPA4 and Lung
Liver Antibodies	>3 publications with CPA4 and Liver
Kidney Antibodies	>3 publications with CPA4 and Kidney
Embryonic Tissue Antibodies	>1 publications with CPA4 and Embryonic Tissue
Vascular Antibodies	>1 publications with CPA4 and Vascular
Heart Antibodies	>1 publications with CPA4 and Heart