ST6GAL1 Recombinant Protein – Cat# MBS146798

ST6 Beta-Galactosamide Alpha-2, 6-Sialyltranferase 1 (ST6GAL1) Recombinant Protein

Name: ST6GAL1 Recombinant Protein; MyBioSource
Brand: MyBioSource
SKU: MBS146798
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146798

Description: ST6GAL1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 389 amino acids (27-406 a.a.) and having a molecular mass of 44.6kDa (Migrates at 40-57kDa on SDS-PAGE under reducing conditions). ST6GAL1 is… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ST6 Beta-Galactosamide Alpha-2, 6-Sialyltranferase 1 (ST6GAL1), Recombinant Protein

Full Product Name

Recombinant Human ST6 Beta-Galactosamide Alpha-2,6-Sialyltranferase 1, Sf9

Product Gene Name

ST6GAL1 recombinant protein

Product Synonym Names

ST6GAL1 Human, sf9; ST6 Beta-Galactoside Alpha-2;6-Sialyltransferase 1; ST6 Beta-Galactosamide Alpha-2;6-Sialyltranferase 1; ST6Gal I; CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2;6-Sialyltransferase 1;B-Cell Antigen CD75; Alpha 2;6-ST 1; EC 2.4.99.1; ST6GalI; SIAT1; CMP-N-Acetylneuraminate Beta-Galactosamide Alpha-2;6-Sialyltransferase; Sialyltransferase 1 (Beta-Galactoside Alpha-2;6-Sialyltransferase); ST6 N-Acetylgalactosaminide Alpha-2;6-Sialyltransferase 1; Sialyltransferase 1; ST6N; ST6 Beta-Galactosamide Alpha-2, 6-Sialyltranferase 1, sf9 Human Recombinant

Sequence

ADP KEKKKGS YYDSFKLQTK EFQVLKSLGK LAMGSDSQSV SSSSTQDPHR GRQTLGSLRG LAKAKPEASF QVWNKDSSSK NLIPRLQKIW KNYLSMNKYK VSYKGPGPGI KFSAEALRCH LRDHVNVSMV EVTDFPFNTS EWEGYLPKES IRTKAGPWGR CAVVSSAGSL KSSQLGREID DHDAVLRFNG APTANFQQDV GTKTTIRLMN SQLVTTEKRF LKDSLYNEGI LIVWDPSVYH SDIPKWYQNP DYNFFNNYKT YRKLHPNQPF YILKPQMPWE LWDILQEISP EEIQPNPPSS GMLGIIIMMT LCDQVDIYEF LPSKRKTDVC YYYQKFFDSA CTMGAYHPLL YEKNLVKHLN QGTDEDIYLL GKATLPGFRT IHCHHHH HH

Host

Sf9, Baculovirus cells

Form/Format

Sterile filtered colorless solution.
ST6GAL1 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Molecular Weight

20,764 Da

OMIM

X17247 mRNA

3D Structure

ModBase 3D Structure for P15907

Product Categories/Family for ST6GAL1 recombinant protein

Enzymes

Other Notes

Small volumes of ST6GAL1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ST6GAL1 purchase

MBS146798 is a recombinant protein targeting ST6GAL1. Also known as Recombinant Human ST6 Beta-Galactosamide Alpha-2,6-Sialyltranferase 1, Sf9. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for ST6GAL1. It may not necessarily be applicable to this product.

NCBI GI #

4506949

NCBI GeneID

6480

NCBI Accession #

NP_003023.1

UniProt Primary Accession #

P15907

UniProt Secondary Accession #

A8KA14; B2R513; D3DNV3

UniProt Related Accession #

P15907

GenBank Nucleotide #

NM_003032.2

NCBI Official Full Name

beta-galactoside alpha-2,6-sialyltransferase 1 isoform a

NCBI Official Synonym Full Names

ST6 beta-galactoside alpha-2,6-sialyltransferase 1

NCBI Official Symbol

ST6GAL1

NCBI Official Synonym Symbols

ST6N; SIAT1; ST6GalI

UniProt Protein Name

Beta-galactoside alpha-2,6-sialyltransferase 1

UniProt Synonym Protein Names

B-cell antigen CD75; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI; Sialyltransferase 1

Protein Family

Beta-galactoside alpha-2,6-sialyltransferase

UniProt Gene Name

ST6GAL1

UniProt Synonym Gene Names

SIAT1; Alpha 2,6-ST 1; ST6GalI

NCBI Protein Information

beta-galactoside alpha-2,6-sialyltransferase 1

NCBI Summary for ST6GAL1

This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009]

UniProt Comments for ST6GAL1

SIAT1: a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. Is normally found in the trans cisternae of the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found.

Protein type: EC 2.4.99.1; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; Transferase

Chromosomal Location of Human Ortholog: 3q27.3

Cellular Component: Golgi membrane

Molecular Function: beta-galactoside alpha-2,6-sialyltransferase activity; protein binding; sialyltransferase activity

Biological Process: humoral immune response; N-acetylneuraminate metabolic process; O-glycan processing; oligosaccharide metabolic process; protein amino acid N-linked glycosylation via asparagine

Research Articles on ST6GAL1

1. High ST6GAL1 expression is associated with aging.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ST6GAL1 recombinant protein

Reference Product	PubMed Publications
CD22 recombinant protein	>3 publications with ST6GAL1 and CD22

Pathways associated with ST6GAL1 recombinant protein

Products by Pathway	Pathway Diagram
Asparagine N-linked Glycosylation Pathway antibodies	Asparagine N-linked Glycosylation Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
N-Glycan Antennae Elongation Pathway antibodies	N-Glycan Antennae Elongation Pathway Diagram
N-Glycan Biosynthesis Pathway antibodies	N-Glycan Biosynthesis Pathway Diagram
N-Glycan Biosynthesis Pathway antibodies	N-Glycan Biosynthesis Pathway Diagram
N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway antibodies	N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway Diagram
N-glycan Biosynthesis, Complex Type Pathway antibodies	N-glycan Biosynthesis, Complex Type Pathway Diagram
N-glycan Biosynthesis, Complex Type Pathway antibodies	N-glycan Biosynthesis, Complex Type Pathway Diagram
O-linked Glycosylation Of Mucins Pathway antibodies	O-linked Glycosylation Of Mucins Pathway Diagram
Other Types Of O-glycan Biosynthesis Pathway antibodies	Other Types Of O-glycan Biosynthesis Pathway Diagram

Diseases associated with ST6GAL1 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>35 publications with ST6GAL1 and Neoplasms
Liver Diseases Antibodies	>8 publications with ST6GAL1 and Liver Diseases
Liver Neoplasms Antibodies	>5 publications with ST6GAL1 and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>3 publications with ST6GAL1 and Carcinoma, Hepatocellular
Inflammation Antibodies	>3 publications with ST6GAL1 and Inflammation
Cell Transformation, Neoplastic Antibodies	>3 publications with ST6GAL1 and Cell Transformation, Neoplastic
Diabetes Mellitus, Type 2 Antibodies	>3 publications with ST6GAL1 and Diabetes Mellitus, Type 2
Hyperplasia Antibodies	>2 publications with ST6GAL1 and Hyperplasia
Disease Models, Animal Antibodies	>2 publications with ST6GAL1 and Disease Models, Animal
Kidney Diseases Antibodies	>2 publications with ST6GAL1 and Kidney Diseases

Organs/Tissues associated with ST6GAL1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>27 publications with ST6GAL1 and Blood
Liver Antibodies	>11 publications with ST6GAL1 and Liver
Lymph Antibodies	>7 publications with ST6GAL1 and Lymph
Lymph Node Antibodies	>7 publications with ST6GAL1 and Lymph Node
Stomach Antibodies	>6 publications with ST6GAL1 and Stomach
Vascular Antibodies	>5 publications with ST6GAL1 and Vascular
Lung Antibodies	>5 publications with ST6GAL1 and Lung
Brain Antibodies	>4 publications with ST6GAL1 and Brain
Bone Antibodies	>3 publications with ST6GAL1 and Bone
Heart Antibodies	>3 publications with ST6GAL1 and Heart