• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

O-Glucosyltransferase 1 (POGLUT1) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146804

Description: POGLUT1 Human Recombinant produced in in Sf9 Baculovirus cells is a single, non-glycosylated polypeptide chain containing 377 amino acids (24-392a.a) and having a molecular mass of 44.5kDa (Migrates at 40-57kDa on SDS-PAGE under reducing… More details

$250 / 0.001 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
O-Glucosyltransferase 1 (POGLUT1), Recombinant Protein
Full Product Name
Recombinant Human Protein O-Glucosyltransferase 1
Product Synonym Names
POGLUT1 Human; POGLUT1; C3orf9; CLP46; hCLP46; KDELCL1; KTELC1; Protein O-glucosyltransferase 1; CAP10-like 46 kDa protein; KTEL motif-containing protein 1; Myelodysplastic syndromes relative protein; O-glucosyltransferase Rumi homolog; hRumi; Protein O-xylosyltransferase; MDSRP; Protein O-Glucosyltransferase 1 Human Recombinant
Sequence
RQKESGSKWK VFIDQINRSL ENYEPCSSQN CSCYHGVIEE DLTPFRGGIS RKMMAEVVRR KLGTHYQITK NRLYRENDCM FPSRCSGVEH FILEVIGRLP DMEMVINVRD YPQVPKWMEP AIPVFSFSKT SEYHDIMYPA WTFWEGGPAV WPIYPTGLGR WDLFREDLVR SAAQWPWKKK NSTAYFRGSR TSPERDPLIL LSRKNPKLVD AEYTKNQAWK SMKDTLGKPA AKDVHLVDHC KYKYLFNFRG VAASFRFKHL FLCGSLVFHV GDEWLEFFYP QLKPWVHYIP VKTDLSNVQE LLQFVKANDD VAQEIAERGS QFIRNHLQMD DITCYWENLL SEYSKFLSYN VTRRKGYDQI IPKMLKTEL< u>L EHHHHHH
Host
Sf9, Baculovirus cells
Form/Format
Sterile filtered colorless solution.
The POGLUT1 solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Molecular Weight
46,189 Da
OMIM
AY298903 mRNA
3D Structure
ModBase 3D Structure for Q8NBL1

Product Categories/Family for POGLUT1 recombinant protein

Other Notes

Small volumes of POGLUT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for POGLUT1 purchase

MBS146804 is a recombinant protein targeting POGLUT1. Also known as Recombinant Human Protein O-Glucosyltransferase 1. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for POGLUT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein O-glucosyltransferase 1
NCBI Official Synonym Full Names
protein O-glucosyltransferase 1
NCBI Official Symbol
POGLUT1
NCBI Official Synonym Symbols
Rumi; CLP46; MDSRP; C3orf9; KTELC1; LGMD2Z; MDS010; hCLP46; KDELCL1
UniProt Protein Name
Protein O-glucosyltransferase 1
UniProt Synonym Protein Names
CAP10-like 46 kDa protein; hCLP46; KTEL motif-containing protein 1; Myelodysplastic syndromes relative protein; O-glucosyltransferase Rumi homolog; hRumi; Protein O-xylosyltransferase (EC:2.4.2.26
UniProt Gene Name
POGLUT1
UniProt Synonym Gene Names
C3orf9; CLP46; KTELC1; MDSRP; hCLP46; hRumi
NCBI Protein Information
protein O-glucosyltransferase 1

NCBI Summary for POGLUT1

This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Show more

UniProt Comments for POGLUT1

KTELC1: UDP-glucosyltransferase. Belongs to the glycosyltransferase 90 family.

Protein type: EC 2.4.2.26; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q13.33

Cellular Component: endoplasmic reticulum lumen

Molecular Function: glucosyltransferase activity; UDP-glucosyltransferase activity; UDP-xylosyltransferase activity

Biological Process: glycolipid metabolic process; positive regulation of Notch signaling pathway; protein amino acid O-linked glycosylation

Disease: Dowling-degos Disease 4; Muscular Dystrophy, Limb-girdle, Type 2z
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000