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Phosphoglycerate Mutase 1 (PGAM1) Mouse Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146827

Description: PGAM1 Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 278 amino acids (1-254) and having a molecular mass of 31.4kDa.PGAM1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Phosphoglycerate Mutase 1 (PGAM1), Active Protein
Full Product Name
Recombinant Mouse Phosphoglycerate Mutase 1, Active
Product Gene Name
PGAM1 active protein
Product Synonym Names
PGAM1 Mouse, Active; Phosphoglycerate mutase 1; BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B; PGAM-B; Pgam1; Pgam-1; 2310050F24Rik; Phosphoglycerate Mutase 1 Mouse Recombinant, Active
Sequence
MGSSHHH HHH SSGLVPRGSH MGSHMA AYKL VLIRHGESAW NLENRFSGWY DADLSPAGHE EAKRGGQALR DAGYEFDICF TSVQKRAIRT LWTVLDAIDQ MWLPVVRTWR LNERHYGGLT GLNKAETAAK HGEAQVKIWR RSYDVPPPPM EPDHPFYSNI SKDRRYADLT EDQLPSCESL KDTIARALPF WNEEIVPQIK EGKRVLIAAH GNSLRGIVKH LEGLSEEAIM ELNLPTGIPI VYELDKNLKP IKPMQFLGDE ETVRKAMEAV AAQGKVKK
Host
E Coli
Form/Format
Sterile filtered clear colorless solution.
The PGAM1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Molecular Weight
28,832 Da
3D Structure
ModBase 3D Structure for Q9DBJ1
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Specific activity is >150units/mg, in which One unit will convert 1.0 umole of 3-phosphoglycerate to 2-phosphoglcerate per minute at pH 7.6 at 37C.

Product Categories/Family for PGAM1 active protein

Enzymes

Other Notes

Small volumes of PGAM1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PGAM1 purchase

MBS146827 is an active protein targeting PGAM1. Also known as Recombinant Mouse Phosphoglycerate Mutase 1, Active. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PGAM1. It may not necessarily be applicable to this product.

NCBI GI #
114326546
NCBI GeneID
18648
NCBI Accession #
NP_075907.2
UniProt Primary Accession #
Q9DBJ1
UniProt Secondary Accession #
Q9D6W0; Q9ERT3
UniProt Related Accession #
Q9DBJ1
GenBank Nucleotide #
NM_023418.2
NCBI Official Full Name
phosphoglycerate mutase 1
NCBI Official Synonym Full Names
phosphoglycerate mutase 1
NCBI Official Symbol
Pgam1
NCBI Official Synonym Symbols
Pgam-1; 2310050F24Rik
UniProt Protein Name
Phosphoglycerate mutase 1
UniProt Synonym Protein Names
BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B; PGAM-B
Protein Family
Phosphoglycerate mutase
UniProt Gene Name
Pgam1
UniProt Synonym Gene Names
PGAM-B
NCBI Protein Information
phosphoglycerate mutase 1

UniProt Comments for PGAM1

PGAM1: Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. Homodimer. In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.

Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 3.1.3.13; EC 5.4.2.11; EC 5.4.2.4; Isomerase; Phosphatase (non-protein)

Chromosomal Location of Human Ortholog: 19|19 C3

Cellular Component: cytoplasm; cytosol; membrane; myelin sheath; nucleus

Molecular Function: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; phosphoglycerate mutase activity; protein kinase binding

Biological Process: gluconeogenesis; glycolysis; regulation of glycolysis; regulation of pentose-phosphate shunt; respiratory burst
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Research Articles on PGAM1

1. PGAM1 correlates with spermatogenic dysfunction and affects the function of cell proliferation, apoptosis and migration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PGAM1 active protein

 Products by Pathway  Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Central Carbon Metabolism In Cancer Pathway antibodies  Central Carbon Metabolism In Cancer Pathway Diagram
 Central Carbon Metabolism In Cancer Pathway antibodies  Central Carbon Metabolism In Cancer Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Gluconeogenesis Pathway antibodies  Gluconeogenesis Pathway Diagram
 Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies  Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram
 Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies  Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram

Diseases associated with PGAM1 active protein

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >4 publications with PGAM1 and Carcinoma
 Disease Models, Animal Antibodies  >3 publications with PGAM1 and Disease Models, Animal
 Carcinoma, Hepatocellular Antibodies  >1 publications with PGAM1 and Carcinoma, Hepatocellular
 Hepatitis Antibodies  >1 publications with PGAM1 and Hepatitis
 Hyperplasia Antibodies  >1 publications with PGAM1 and Hyperplasia
 Liver Neoplasms Antibodies  >1 publications with PGAM1 and Liver Neoplasms
 Necrosis Antibodies  >1 publications with PGAM1 and Necrosis
 Carcinoma, Non-Small-Cell Lung Antibodies  >1 publications with PGAM1 and Carcinoma, Non-Small-Cell Lung
 Mammary Neoplasms, Animal Antibodies  >1 publications with PGAM1 and Mammary Neoplasms, Animal
 Carcinoma, Squamous Cell Antibodies  >1 publications with PGAM1 and Carcinoma, Squamous Cell

Organs/Tissues associated with PGAM1 active protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >13 publications with PGAM1 and Brain
 Blood Antibodies  >6 publications with PGAM1 and Blood
 Muscle Antibodies  >4 publications with PGAM1 and Muscle
 Heart Antibodies  >3 publications with PGAM1 and Heart
 Liver Antibodies  >3 publications with PGAM1 and Liver
 Lung Antibodies  >3 publications with PGAM1 and Lung
 Testis Antibodies  >3 publications with PGAM1 and Testis
 Ovary Antibodies  >2 publications with PGAM1 and Ovary
 Kidney Antibodies  >2 publications with PGAM1 and Kidney
 Artery Antibodies  >2 publications with PGAM1 and Artery
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