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Histone-Lysine N-Methyltransferase SUVR2 (SUVR2) Arabidopsis Thaliana Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1468880

MBS1468880 is a recombinant protein targeting SUVR2. Also known as Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase SUVR2 (SUVR2) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Histone-lysine N-methyltransferase SUVR2 (SUVR2), Recombinant Protein
Full Product Name
Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase SUVR2 (SUVR2) , partial
Product Gene Name
SUVR2 recombinant protein
Product Synonym Gene Name
SUVR2
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
79,363 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9FNC7
Species
Arabidopsis thaliana (Mouse-ear cress)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SUVR2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SUVR2. It may not necessarily be applicable to this product.

NCBI GI #
145334713
NCBI GeneID
834422
NCBI Accession #
NP_001078702.1
UniProt Primary Accession #
Q9FNC7
UniProt Secondary Accession #
Q0WKU5; Q941L4
UniProt Related Accession #
Q9FNC7
GenBank Nucleotide #
NM_001085233.2
NCBI Official Full Name
SET-domain containing protein lysine methyltransferase family protein
NCBI Official Symbol
SUVR2
NCBI Official Synonym Symbols
MRH10.10; MRH10_10; SDG18; SET DOMAIN PROTEIN 18
UniProt Protein Name
Probable inactive histone-lysine N-methyltransferase SUVR2
UniProt Synonym Protein Names
Protein SET DOMAIN GROUP 18; Suppressor of variegation 3-9-related protein 2; Su(var)3-9-related protein 2
Protein Family
Probable inactive histone-lysine N-methyltransferase
UniProt Gene Name
SUVR2
UniProt Synonym Gene Names
SDG18; SET18; Su(var)3-9-related protein 2
NCBI Protein Information
SET-domain containing protein lysine methyltransferase family protein

NCBI Summary for SUVR2

Encodes SUVR2, one of the four closely related Arabidopsis SUVR proteins that belong to the SU(VAR)3-9 subgroup of SET-domain proteins. Proteins containing the evolutionarily conserved SET domain are involved in regulation of eukaryotic gene expression and chromatin structure through their histone lysine methyltransferase (HMTase) activity. SUVR1, SUVR2 and SUVR4 proteins contain a novel domain at their N-terminus, and a SUVR specific region preceding the SET domain. Localized to the nucleolus, maybe involved in regulation of rRNA expression.
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UniProt Comments for SUVR2

Probable inactive histone-lysine methyltransferase that acts as regulator of transctiptional gene silencing independently of histone H3K9 methylation. Contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci. Forms a complex with SUVR1 and associates with the SNF2-related chromatin-remodeling proteins CHR19, CHR27, and CHR28, thereby mediating nucleosome positioning and transcriptional silencing. Does not possess histone-lysine methyltransferase activity in vitro, and the conserved catalytic sites of SUVR2 are dispensable for its function in transcriptional gene silencing.
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Research Articles on SUVR2

1. This study suggests that the involvement of SUVR2 in transcriptional gene silencing is related to nucleosome positioning mediated by its associated chromatin-remodeling proteins.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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