Mouse LAMP2 Recombinant Protein – Cat# MBS146908

Lysosomal-Associated Membrane Protein 2 (LAMP2) Mouse Recombinant Protein

Name: LAMP2 Recombinant Protein; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS146908
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146908

LAMP2 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 362 amino acids (26-379 a.a.) and having a molecular mass of 40.2kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). LAMP2 is… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lysosomal-Associated Membrane Protein 2 (LAMP2), Recombinant Protein

Full Product Name

Recombinant Mouse Lysosomal-Associated Membrane Protein 2

Product Gene Name

LAMP2 recombinant protein

Product Synonym Names

LAMP2 Mouse; Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B; Lysosomal membrane glycoprotein type B; LGP-B; CD107b; Lysosomal-Associated Membrane Protein 2 Mouse Recombinant

Sequence

LIVNLTDSKG TCLYAEWEMN FTITYETTNQ TNKTITIAVP DKATHDGSSC GDDRNSAKIM IQFGFAVSWA VNFTKEASHY SIHDIVLSYN TSDSTVFPGA VAKGVHTVKN PENFKVPLDV IFKCNSVLTY NLTPVVQKYW GIHLQAFVQN GTVSKNEQVC EEDQTPTTVA PIIHTTAPST TTTLTPTSTP TPTPTPTPTV GNYSIRNGNT TCLLATMGLQ LNITEEKVPF IFNINPATTN FTGSCQPQSA QLRLNNSQIK YLDFIFAVKN EKRFYLKEVN VYMYLANGSA FNISNKNLSF WDAPLGSSYM CNKEQVLSVS RAFQINTFNL KVQPFNVTKG QYSTAQDCSA DEDNLEH HHH HH

Host

Sf9, Baculovirus cells

Form/Format

Sterile filtered clear solution.
LAMP2 protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.

3D Structure

ModBase 3D Structure for P17047

Product Categories/Family for LAMP2 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of LAMP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LAMP2 purchase

MBS146908 is a recombinant protein targeting LAMP2. Also known as Recombinant Mouse Lysosomal-Associated Membrane Protein 2. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for LAMP2. It may not necessarily be applicable to this product.

NCBI GI #

63054837

NCBI GeneID

16784

NCBI Accession #

NP_001017959.1

UniProt Primary Accession #

P17047

UniProt Secondary Accession #

Q3TXG5; Q8BSG8; A2A430

UniProt Related Accession #

P17047

GenBank Nucleotide #

NM_001017959.2

NCBI Official Full Name

lysosome-associated membrane glycoprotein 2 isoform 1

NCBI Official Synonym Full Names

lysosomal-associated membrane protein 2

NCBI Official Symbol

Lamp2

NCBI Official Synonym Symbols

Mac3; LGP-B; CD107b; Lamp-2; Lamp II; Lamp-2a; Lamp-2b; Lamp-2c

UniProt Protein Name

Lysosome-associated membrane glycoprotein 2

UniProt Synonym Protein Names

CD107 antigen-like family member B; Lysosomal membrane glycoprotein type B; LGP-B; CD_antigen: CD107b

Protein Family

Lysosome-associated membrane glycoprotein

UniProt Gene Name

Lamp2

UniProt Synonym Gene Names

Lamp-2; LAMP-2; Lysosome-associated membrane protein 2; LGP-B

NCBI Protein Information

lysosome-associated membrane glycoprotein 2

UniProt Comments for LAMP2

LAMP2: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. Defects in LAMP2 are the cause of Danon disease (DAND); also known as glycogen storage disease type 2B (GSD2B). DAND is a lysosomal glycogen storage disease characterized by the clinical triad of cardiomyopathy, vacuolar myopathy and mental retardation. It is often associated with an accumulation of glycogen in muscle and lysosomes. Belongs to the LAMP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: X A3.3|X 22.67 cM

Cellular Component: endosome; extracellular space; late endosome; late endosome membrane; lipid raft; lysosomal membrane; lysosome; membrane; phagocytic vesicle membrane; platelet dense granule membrane

Molecular Function: enzyme binding; protein domain specific binding

Biological Process: muscle maintenance; protein stabilization; regulation of protein stability

Research Articles on LAMP2

1. LAMP-2 in the central nervous system has a possible role in the degradation of the various macromolecules in lysosomes and an additional function concerning protection from oxidative stress, especially in the substantia nigra.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LAMP2 recombinant protein

Reference Product	PubMed Publications
Rab7 recombinant protein	>17 publications with LAMP2 and Rab7
Cd63 recombinant protein	>11 publications with LAMP2 and Cd63
Hspa8 recombinant protein	>9 publications with LAMP2 and Hspa8
Uchl1 recombinant protein	>1 publications with LAMP2 and Uchl1
Gba recombinant protein	>1 publications with LAMP2 and Gba
Anxa4 recombinant protein	>1 publications with LAMP2 and Anxa4

Pathways associated with LAMP2 recombinant protein

Products by Pathway	Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Platelet Activation, Signaling And Aggregation Pathway antibodies	Platelet Activation, Signaling And Aggregation Pathway Diagram
Platelet Degranulation Pathway antibodies	Platelet Degranulation Pathway Diagram
Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies	Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram
Senescence And Autophagy Pathway antibodies	Senescence And Autophagy Pathway Diagram
Tuberculosis Pathway antibodies	Tuberculosis Pathway Diagram

Diseases associated with LAMP2 recombinant protein

Disease Name	Pubmed Publications
Heart Diseases Antibodies	>81 publications with LAMP2 and Heart Diseases
Cardiomyopathies Antibodies	>73 publications with LAMP2 and Cardiomyopathies
Neurobehavioral Manifestations Antibodies	>54 publications with LAMP2 and Neurobehavioral Manifestations
Glycogen Storage Disease Type IIb Antibodies	>53 publications with LAMP2 and Glycogen Storage Disease Type IIb
Disease Models, Animal Antibodies	>23 publications with LAMP2 and Disease Models, Animal
Immune System Diseases Antibodies	>18 publications with LAMP2 and Immune System Diseases
Cardiomegaly Antibodies	>17 publications with LAMP2 and Cardiomegaly
Inflammation Antibodies	>17 publications with LAMP2 and Inflammation
Kidney Diseases Antibodies	>14 publications with LAMP2 and Kidney Diseases
Movement Disorders Antibodies	>14 publications with LAMP2 and Movement Disorders

Organs/Tissues associated with LAMP2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>51 publications with LAMP2 and Brain