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Patatin-Like Phospholipase Domain-Containing Protein 2 (PNPLA2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146979

PNPLA2 is an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in the PNPLA2 gene are linked to neutral lipid storage disease with myopathy. More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Patatin-like phospholipase domain-containing protein 2 (PNPLA2), Monoclonal Antibody
Full Product Name
Mouse Anti Human Patatin-like phospholipase domain-containing protein 2, Clone PAT18E6AT
Product Gene Name
Product Synonym Names
Patatin-like phospholipase domain-containing protein 2; Adipose triglyceride lipase; Desnutrin Transport-secretion protein 2; TTS2.2; Calcium-independent phospholipase A2; IPLA2-zeta Pigment epithelium-derived factor; TTS2; PNPLA2; ATGL; PEDF-R; FP17548; TTS-2.2; DKFZp667M109; 1110001C14Rik; PNPLA2 PAT18E6AT Antibody; Patatin-like phospholipase domain-containing protein 2, Clone PAT18E6AT, Mouse Anti Human
Clonality
Monoclonal
Isotype
IgG2b heavy chain and k light chain
Clone Number
PAT18E6AT
Host
Mouse
Species Reactivity
Human
Form/Format
Sterile filtered colorless solution
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide
Purity/Purification
Purified from mouse ascitic fluids by protein-A affinity chromatography
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at-20 degree C.
Prevent freeze thaw cycles
Molecular Weight
19,875 Da
OMIM
AY894804 mRNA
3D Structure
ModBase 3D Structure for Q96AD5
Immunogen
Anti-human PNPLA2 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PNPLA2 protein 30-504 amino acids purified from E Coli
Applications Tested/Suitable for anti-PNPLA2 antibody
ELISA (EIA), Western Blot (WB), Flow cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Other Notes

Small volumes of anti-PNPLA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PNPLA2 purchase

MBS146979 is an antibody targeting PNPLA2. Also known as Mouse Anti Human Patatin-like phospholipase domain-containing protein 2, Clone PAT18E6AT. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PNPLA2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Patatin-like phospholipase domain-containing protein 2
NCBI Official Synonym Full Names
patatin like phospholipase domain containing 2
NCBI Official Symbol
PNPLA2
NCBI Official Synonym Symbols
ATGL; TTS2; PEDF-R; FP17548; TTS-2.2; iPLA2zeta; 1110001C14Rik
UniProt Protein Name
Patatin-like phospholipase domain-containing protein 2
UniProt Synonym Protein Names
Adipose triglyceride lipase; Calcium-independent phospholipase A2; Desnutrin; IPLA2-zeta; Pigment epithelium-derived factor; TTS2.2; Transport-secretion protein 2; TTS2
UniProt Gene Name
PNPLA2
UniProt Synonym Gene Names
ATGL; TTS2
NCBI Protein Information
patatin-like phospholipase domain-containing protein 2

NCBI Summary for PNPLA2

This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy. [provided by RefSeq, Jul 2010]

UniProt Comments for PNPLA2

Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674). Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes (PubMed:16239926). May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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