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Four and A Half LIM Domains 2 (FHL2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS147011

Four And A Half LIM Domains 2 (FHL2) belongs to the four-and-a-half-LIM-only protein family. Family members are comprised of 2 highly conserved, tandemly arranged, zinc finger domains with 4 highly conserved cysteines binding a zinc atom in each zinc finger.… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Four And A Half LIM Domains 2 (FHL2), Monoclonal Antibody
Full Product Name
Mouse Anti Human Four And A Half LIM Domains 2
Product Gene Name
Product Synonym Names
AAG11; DRAL; FHL-2; SLIM-3; SLIM3; Four and a half LIM domains protein 2; LIM domain protein DRAL; Skeletal muscle LIM-protein 3; FHL2; RNA Binding Motif Protein 18; RNA-Binding Motif Protein 18; RBM18; FHL2 Antibody; Mouse Anti Human Four And A Half LIM Domains 2
Clonality
Monoclonal
Isotype
IgG1 heavy chain and k light chain
Clone Number
PAT21D11AT
Host
Mouse
Species Reactivity
Human
Form/Format
Sterile filtered colorless solution
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide
Purity/Purification
Purified from mouse ascitic fluids by protein-A affinity chromatography
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at-20 degree C.
Prevent freeze thaw cycles
Molecular Weight
15,890 Da
OMIM
L42176 mRNA
Immunogen
Anti-human FHL2 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FHL2 protein 1-279 amino acids purified from E Coli
Applications Tested/Suitable for anti-FHL2 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-FHL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FHL2 purchase

MBS147011 is an antibody targeting FHL2. Also known as Mouse Anti Human Four And A Half LIM Domains 2. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FHL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Four and a half LIM domains 2
NCBI Official Synonym Full Names
four and a half LIM domains 2
NCBI Official Symbol
FHL2
NCBI Official Synonym Symbols
DRAL; AAG11; FHL-2; SLIM3; SLIM-3
UniProt Protein Name
Four and a half LIM domains protein 2
UniProt Synonym Protein Names
LIM domain protein DRAL; Skeletal muscle LIM-protein 3; SLIM-3
UniProt Gene Name
FHL2
UniProt Synonym Gene Names
DRAL; SLIM3; FHL-2; SLIM-3
NCBI Protein Information
four and a half LIM domains protein 2

NCBI Summary for FHL2

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2016]
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UniProt Comments for FHL2

May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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