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Stabilin-2 (STAB2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1470645

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Stabilin-2 (Stab2), Recombinant Protein
Full Product Name
Recombinant Mouse Stabilin-2 (Stab2) , partial
Product Gene Name
Stab2 recombinant protein
Product Synonym Gene Name
Stab2
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
277,532 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q8R4U0
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Stab2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Stab2 purchase

MBS1470645 is a recombinant protein targeting Stab2. Also known as Recombinant Mouse Stabilin-2 (Stab2) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Stab2. It may not necessarily be applicable to this product.

NCBI GI #
20149764
NCBI GeneID
192188
NCBI Accession #
NP_619614.1
UniProt Primary Accession #
Q8R4U0
UniProt Secondary Accession #
Q8BM87
UniProt Related Accession #
Q8R4U0
GenBank Nucleotide #
NM_138673.2
NCBI Official Full Name
stabilin-2
NCBI Official Synonym Full Names
stabilin 2
NCBI Official Symbol
Stab2
NCBI Official Synonym Symbols
FELL; FEEL-2; STAB-2; MFEEL-2
UniProt Protein Name
Stabilin-2
UniProt Synonym Protein Names
Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; FEEL-2
Protein Family
Stabilin
UniProt Gene Name
Stab2
UniProt Synonym Gene Names
FEEL-2
NCBI Protein Information
stabilin-2

UniProt Comments for Stab2

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed short form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.
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Research Articles on Stab2

1. Stab2 recognizes phospatidylserine exposed on apoptotic cells for sensing as an "eat-me" signal.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Stab2 recombinant protein

 Reference Product  PubMed Publications
 Cd44 recombinant protein  >11 publications with Stab2 and Cd44
 Lyve1 recombinant protein  >3 publications with Stab2 and Lyve1
 Hoxc9 recombinant protein  >1 publications with Stab2 and Hoxc9

Pathways associated with Stab2 recombinant protein

 Products by Pathway  Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Hyaluronan Metabolism Pathway antibodies  Hyaluronan Metabolism Pathway Diagram
 Hyaluronan Uptake And Degradation Pathway antibodies  Hyaluronan Uptake And Degradation Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 Scavenging By Class H Receptors Pathway antibodies  Scavenging By Class H Receptors Pathway Diagram
 Vesicle-mediated Transport Pathway antibodies  Vesicle-mediated Transport Pathway Diagram

Diseases associated with Stab2 recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >5 publications with Stab2 and Inflammation
 Liver Diseases Antibodies  >4 publications with Stab2 and Liver Diseases
 Disease Models, Animal Antibodies  >3 publications with Stab2 and Disease Models, Animal
 Liver Neoplasms Antibodies  >3 publications with Stab2 and Liver Neoplasms
 Adenocarcinoma Antibodies  >2 publications with Stab2 and Adenocarcinoma
 Neoplasm Metastasis Antibodies  >2 publications with Stab2 and Neoplasm Metastasis
 Fibrosis Antibodies  >1 publications with Stab2 and Fibrosis
 Growth Disorders Antibodies  >1 publications with Stab2 and Growth Disorders
 Kidney Diseases Antibodies  >1 publications with Stab2 and Kidney Diseases
 Hypertension Antibodies  >1 publications with Stab2 and Hypertension

Organs/Tissues associated with Stab2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >27 publications with Stab2 and Liver
 Lymph Node Antibodies  >14 publications with Stab2 and Lymph Node
 Spleen Antibodies  >12 publications with Stab2 and Spleen
 Brain Antibodies  >5 publications with Stab2 and Brain
 Kidney Antibodies  >4 publications with Stab2 and Kidney
 Embryonic Tissue Antibodies  >4 publications with Stab2 and Embryonic Tissue
 Eye Antibodies  >2 publications with Stab2 and Eye
 Lung Antibodies  >1 publications with Stab2 and Lung
 Mammary Gland Antibodies  >1 publications with Stab2 and Mammary Gland
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