Human TNFRSF4 Recombinant Protein – Cat# MBS147066

TNF Receptor Superfamily Member 4 (TNFRSF4) Human Recombinant Protein

Name: TNFRSF4 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS147066
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS147066

Description: TNFRSF4 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 425 amino acids (29-214a.a.) and having a molecular mass of 46.9Da. (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). TNFRSF4 is… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TNF Receptor Superfamily Member 4 (TNFRSF4), Recombinant Protein

Full Product Name

Recombinant Human TNF Receptor Superfamily Member 4

Product Gene Name

TNFRSF4 recombinant protein

Product Synonym Names

TNFRSF4; TNF Receptor Superfamily Member 4; TAX Transcriptionally-Activated Glycoprotein 1 Receptor; OX40L Receptor; ACT35 Antigen; CD134 Antigen; TXGP1L; Tax-Transcriptionally Activated Glycoprotein 1 Receptor; Tumor Necrosis Factor Receptor Superfamily; Member 4; Tumor Necrosis Factor Receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40 Cell Surface Antigen; OX40 Homologue; ATC35 Antigen; OX40 Antigen; ACT35; CD134; IMD16; OX40. ; TNFRSF4 Human; TNF Receptor Superfamily Member 4 Human Recombinant

Sequence

LHCVGDTYPS NDRCCHECRP GNGMVSRCSR SQNTVCRPCG PGFYNDVVSS KPCKPCTWCN LRSGSERKQL CTATQDTVCR CRAGTQPLDS YKPGVDCAPC PPGHFSPGDN QACKPWTNCT LAGKHTLQPA SNSSDAICED RDPPATQPQE TQGPPARPIT VQPTEAWPRT SQGPSTRPVE VPGGRALEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH

Host

Sf9, Baculovirus cells

Form/Format

Sterile filtered colorless solution
Protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles

Molecular Weight

29,341 Da

OMIM

X75962 mRNA

3D Structure

ModBase 3D Structure for P43489

Product Categories/Family for TNFRSF4 recombinant protein

Cytokines and Growth Factors; Cytokines; Tumor Necrosis Factor; TNFRSF4 Human

Other Notes

Small volumes of TNFRSF4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TNFRSF4 purchase

MBS147066 is a recombinant protein targeting TNFRSF4. Also known as Recombinant Human TNF Receptor Superfamily Member 4. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for TNFRSF4. It may not necessarily be applicable to this product.

NCBI GI #

1171933

NCBI GeneID

7293

NCBI Accession #

P43489.1

UniProt Primary Accession #

P43489

UniProt Secondary Accession #

Q13663; Q2M312; Q5T7M0

UniProt Related Accession #

P43489

NCBI Official Full Name

Tumor necrosis factor receptor superfamily member 4

NCBI Official Synonym Full Names

TNF receptor superfamily member 4

NCBI Official Symbol

TNFRSF4

NCBI Official Synonym Symbols

OX40; ACT35; CD134; IMD16; TXGP1L

UniProt Protein Name

Tumor necrosis factor receptor superfamily member 4

UniProt Synonym Protein Names

ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD_antigen: CD134

Protein Family

Tumor necrosis factor receptor superfamily

UniProt Gene Name

TNFRSF4

UniProt Synonym Gene Names

TXGP1L

NCBI Protein Information

tumor necrosis factor receptor superfamily member 4

NCBI Summary for TNFRSF4

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]

UniProt Comments for TNFRSF4

Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.

Research Articles on TNFRSF4

1. this study demonstrates that cSCCs contain an abundance of Tregs which can suppress tumoral effector T cell function and that activation of the costimulatory receptor OX40 enhances tumoral T cell responses.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TNFRSF4 recombinant protein

Reference Product	PubMed Publications
TNFSF4 recombinant protein	>190 publications with TNFRSF4 and TNFSF4
TNFRSF9 recombinant protein	>40 publications with TNFRSF4 and TNFRSF9
IL2RA recombinant protein	>15 publications with TNFRSF4 and IL2RA
TNFSF9 recombinant protein	>7 publications with TNFRSF4 and TNFSF9
IL2RG recombinant protein	>3 publications with TNFRSF4 and IL2RG
IL2RB recombinant protein	>3 publications with TNFRSF4 and IL2RB
TRAF1 recombinant protein	>2 publications with TNFRSF4 and TRAF1
TRAF5 recombinant protein	>2 publications with TNFRSF4 and TRAF5

Pathways associated with TNFRSF4 recombinant protein

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Downstream Signaling In Naive CD8+ T Cells Pathway antibodies	Downstream Signaling In Naive CD8+ T Cells Pathway Diagram

Diseases associated with TNFRSF4 recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>294 publications with TNFRSF4 and Necrosis
Immune System Diseases Antibodies	>123 publications with TNFRSF4 and Immune System Diseases
Autoimmune Diseases Antibodies	>58 publications with TNFRSF4 and Autoimmune Diseases
Disease Models, Animal Antibodies	>56 publications with TNFRSF4 and Disease Models, Animal
Inflammation Antibodies	>49 publications with TNFRSF4 and Inflammation
Lung Diseases Antibodies	>23 publications with TNFRSF4 and Lung Diseases
Nervous System Diseases Antibodies	>23 publications with TNFRSF4 and Nervous System Diseases
Cardiovascular Diseases Antibodies	>21 publications with TNFRSF4 and Cardiovascular Diseases
Neoplasms, Experimental Antibodies	>21 publications with TNFRSF4 and Neoplasms, Experimental
Brain Diseases Antibodies	>14 publications with TNFRSF4 and Brain Diseases

Organs/Tissues associated with TNFRSF4 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>341 publications with TNFRSF4 and Blood
Lymph Node Antibodies	>47 publications with TNFRSF4 and Lymph Node
Lung Antibodies	>23 publications with TNFRSF4 and Lung
Skin Antibodies	>22 publications with TNFRSF4 and Skin
Intestine Antibodies	>8 publications with TNFRSF4 and Intestine
Kidney Antibodies	>6 publications with TNFRSF4 and Kidney
Stomach Antibodies	>1 publications with TNFRSF4 and Stomach