Human ACP5 Active Protein – Cat# MBS147092

Acid Phosphatase-5 (ACP5) Human Active Protein

Name: ACP5 Active Protein; Acid Phosphatase-5; Human; MyBioSource
Brand: MyBioSource
SKU: MBS147092
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS147092

Description: ACP5 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 304 amino acids (22-325 a.a.) and having a molecular mass of 34.3kDa (Migrates at 28-40kDa on SDS-PAGE under reducing conditions).… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Acid Phosphatase-5 (ACP5), Active Protein

Full Product Name

Recombinant Human Acid Phosphatase-5

Product Gene Name

ACP5 active protein

Product Synonym Names

Acid Phosphatase 5; Tartrate Resistant; Tartrate-Resistant Acid ATPase; Human Purple Acid Phosphatase; EC 3.1.3.2; TrATPase; Tartrate-Resistant Acid Phosphatase Type 5; Tartrate-Resistant Acid Phosphatase 5a; Tartrate-Resistant Acid Phosphatase 5b; Tartrate-Resistant Acid Phosphatase; Type 5 Acid Phosphatase; TRACP5a; TRACP5b; TR-AP; HPAP; TRAP; ACP5; ACP5 Human; Acid Phosphatase-5 Human Recombinant

Sequence

ATPALRFVAV GDWGGVPNAP FHTAREMANA KEIARTVQIL GADFILSLGD NFYFTGVQDI NDKRFQETFE DVFSDRSLRK VPWYVLAGNH DHLGNVSAQI AYSKISKRWN FPSPFYRLHF KIPQTNVSVA IFMLDTVTLC GNSDDFLSQQ PERPRDVKLA RTQLSWLKKQ LAAAREDYVL VAGHYPVWSI AEHGPTHCLV KQLRPLLATY GVTAYLCGHD HNLQYLQDEN GVGYVLSGAG NFMDPSKRHQ RKVPNGYLRF HYGTEDSLGG FAYVEISSKE MTVTYIEASG KSLFKTRLPR RARP

Host

Sf9, Baculovirus cells

Form/Format

Sterile filtered colorless solution
Protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles

Molecular Weight

36,599 Da

OMIM

J04430 mRNA

3D Structure

ModBase 3D Structure for P13686

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Specific activity is >10, 000 units/mg, and is defined as the amount of enzyme that hydrolyze 1.0 nmoles of p-nitrophenyl phosphate (pNPP) per minute at pH 5.0 at 37 degree C

Product Categories/Family for ACP5 active protein

Enzymes; Phosphatase; ACP5 Human

Other Notes

Small volumes of ACP5 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ACP5 purchase

MBS147092 is an active protein targeting ACP5. Also known as Recombinant Human Acid Phosphatase-5. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for ACP5. It may not necessarily be applicable to this product.

NCBI GI #

56757583

NCBI GeneID

NCBI Accession #

P13686.3

UniProt Primary Accession #

P13686

UniProt Secondary Accession #

Q2TAB1; Q6IAS6; Q9UCJ5; Q9UCJ6; Q9UCJ7; A8K3V2

UniProt Related Accession #

P13686

NCBI Official Full Name

Tartrate-resistant acid phosphatase type 5

NCBI Official Synonym Full Names

acid phosphatase 5, tartrate resistant

NCBI Official Symbol

ACP5

NCBI Official Synonym Symbols

HPAP; TRAP; TRACP5a; TRACP5b; TrATPase

UniProt Protein Name

Tartrate-resistant acid phosphatase type 5

UniProt Synonym Protein Names

Tartrate-resistant acid ATPase; TrATPase; Type 5 acid phosphatase

Protein Family

Acyl carrier protein

UniProt Gene Name

ACP5

UniProt Synonym Gene Names

TR-AP; TrATPase

NCBI Protein Information

tartrate-resistant acid phosphatase type 5

NCBI Summary for ACP5

This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008]

UniProt Comments for ACP5

Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.

Research Articles on ACP5

1. Nidogen-2, a protein shown to be expressed intracellularly and for secretion by pre-adipocytes, was shown to interact, through its globular G3 domain, with TRAP 5a in vitro.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ACP5 active protein

Reference Product	PubMed Publications
CSF1R active protein	>7 publications with ACP5 and CSF1R
SPP1 active protein	>6 publications with ACP5 and SPP1

Pathways associated with ACP5 active protein

Products by Pathway	Pathway Diagram
Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies	Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram
Defective BTD Causes Biotidinase Deficiency Pathway antibodies	Defective BTD Causes Biotidinase Deficiency Pathway Diagram
Defective CD320 Causes Methylmalonic Aciduria Pathway antibodies	Defective CD320 Causes Methylmalonic Aciduria Pathway Diagram
Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies	Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram
Defective GIF Causes Intrinsic Factor Deficiency Pathway antibodies	Defective GIF Causes Intrinsic Factor Deficiency Pathway Diagram
Defective HLCS Causes Multiple Carboxylase Deficiency Pathway antibodies	Defective HLCS Causes Multiple Carboxylase Deficiency Pathway Diagram
Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway antibodies	Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway Diagram
Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway antibodies	Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway Diagram
Defective MMAB Causes Methylmalonic Aciduria Type CblB Pathway antibodies	Defective MMAB Causes Methylmalonic Aciduria Type CblB Pathway Diagram
Defective MMACHC Causes Methylmalonic Aciduria And Homocystinuria Type CblC Pathway antibodies	Defective MMACHC Causes Methylmalonic Aciduria And Homocystinuria Type CblC Pathway Diagram

Diseases associated with ACP5 active protein

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>4 publications with ACP5 and Liver Diseases
Inflammation Antibodies	>4 publications with ACP5 and Inflammation
Necrosis Antibodies	>3 publications with ACP5 and Necrosis
Carcinoma, Hepatocellular Antibodies	>2 publications with ACP5 and Carcinoma, Hepatocellular
Lung Diseases Antibodies	>2 publications with ACP5 and Lung Diseases
Atherosclerosis Antibodies	>2 publications with ACP5 and Atherosclerosis
Spondyloenchondrodysplasia Antibodies	>2 publications with ACP5 and Spondyloenchondrodysplasia
Obesity Antibodies	>2 publications with ACP5 and Obesity
Cardiovascular Diseases Antibodies	>1 publications with ACP5 and Cardiovascular Diseases
Hepatomegaly Antibodies	>1 publications with ACP5 and Hepatomegaly

Organs/Tissues associated with ACP5 active protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>42 publications with ACP5 and Bone
Blood Antibodies	>9 publications with ACP5 and Blood
Liver Antibodies	>8 publications with ACP5 and Liver
Connective Tissue Antibodies	>7 publications with ACP5 and Connective Tissue
Lung Antibodies	>3 publications with ACP5 and Lung
Uterus Antibodies	>2 publications with ACP5 and Uterus
Kidney Antibodies	>2 publications with ACP5 and Kidney
Brain Antibodies	>2 publications with ACP5 and Brain
Eye Antibodies	>1 publications with ACP5 and Eye
Parathyroid Antibodies	>1 publications with ACP5 and Parathyroid