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Dicarbonyl/L-Xylulose Reductase (DCXR) Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS147096

Description: DCXR Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 264 amino acids (1-244 a.a.) and having a molecular mass of 28 kDa. The DCXR is fused to a 20 amino acids His-Tag at N-terminus and purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Dicarbonyl/L-Xylulose Reductase (DCXR), Active Protein
Full Product Name
Recombinant Human Dicarbonyl/L-Xylulose Reductase, Bioactive
Product Gene Name
Product Synonym Names
DCR; HCR2; HCRII; KIDCR; P34H; SDR20C1; Dicarbonyl/L-Xylulose Reductase; EC=1.1.1.10; Carbonyl reductase II; Kidney dicarbonyl reductase; Sperm surface protein P34H; DCXR Human, Bioactive; Dicarbonyl/L-Xylulose Reductase Human Recombinant, Bioactive
Sequence
MGSSHHHHHH SSGLVPRGSH MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG FWAC
Host
Escherichia Coli
Form/Format
Sterile filtered colorless solution
(0.5mg/ml) solution containing 20mM Tris-HClbuffer (pH 8.0), 1mM DTT, 20% glycerol and 50mM NaCl
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
Molecular Weight
25,913 Da
OMIM
AB013846 mRNA
3D Structure
ModBase 3D Structure for Q7Z4W1
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Specific activity is > 1, 800 pmol/min/ug and isdefined as the amount of enzyme that oxidize 1pmole of xylitol to L-xyluloseper minute at pH 10.0 at 37C

Product Categories/Family for DCXR active protein

Other Notes

Small volumes of DCXR active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DCXR purchase

MBS147096 is an active protein targeting DCXR. Also known as Recombinant Human Dicarbonyl/L-Xylulose Reductase, Bioactive. Host: Escherichia Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for DCXR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
L-xylulose reductase
NCBI Official Synonym Full Names
dicarbonyl and L-xylulose reductase
NCBI Official Symbol
DCXR
NCBI Official Synonym Symbols
XR; DCR; HCR2; P34H; HCRII; KIDCR; PNTSU; SDR20C1
UniProt Protein Name
L-xylulose reductase
UniProt Synonym Protein Names
Carbonyl reductase II; Dicarbonyl/L-xylulose reductase; Kidney dicarbonyl reductase; kiDCR; Short chain dehydrogenase/reductase family 20C member 1; Sperm surface protein P34H
UniProt Gene Name
DCXR
UniProt Synonym Gene Names
SDR20C1; XR; kiDCR
NCBI Protein Information
L-xylulose reductase

NCBI Summary for DCXR

The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]
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UniProt Comments for DCXR

Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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