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ELMO Domain-Containing Protein 3 (ELMOD3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1470976

MBS1470976 is a recombinant protein targeting ELMOD3. Also known as Recombinant Human ELMO domain-containing protein 3 (ELMOD3). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1115 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ELMO domain-containing protein 3 (ELMOD3), Recombinant Protein
Full Product Name
Recombinant Human ELMO domain-containing protein 3 (ELMOD3)
Product Gene Name
ELMOD3 recombinant protein
Product Synonym Gene Name
ELMOD3
Sequence
MNEKSCSFHS KEELRDGQGE RLSAGYSPSY DKDKSVLAFR GIPISELKNH GILQALTTEA YEWEPRVVST EVVRAQEEWE AVDTIQPETG SQASSEQPGQ LISFSEALQH FQTVDLSPFK KRIQPTIRRT GLAALRHYLF GPPKLHQRLR EERDLVLTIA QCGLDSQDPV HGRVLQTIYK KLTGSKFDCA LHGNHWEDLG FQGANPATDL RGAGFLALLH LLYLVMDSKT LPMAQEIFRL SRHHIQQFPF CLMSVNITHI AIQALREECL SRECNRQQKV IPVVNSFYAA TFLHLAHVWR TQRKTISDSG FVLKELEVLA KKSPRRLLKT LELYLARVSK GQASLLGAQK CYGPEAPPFK DLTFTGESDL QSHSSEGVWL I
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
44,344 Da
Sequence Positions
1-381, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
615427
3D Structure
ModBase 3D Structure for Q96FG2
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ELMOD3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ELMOD3. It may not necessarily be applicable to this product.

NCBI GI #
203098474
NCBI GeneID
84173
NCBI Accession #
NP_001128493.1
UniProt Primary Accession #
Q96FG2
UniProt Secondary Accession #
Q2M1K3; Q2XSU3; Q2XSU4; Q8NAC1; Q8TCK4; Q8WV70; Q8WY75; Q9H6Q8; B8ZZD6; D6W5K4
UniProt Related Accession #
Q96FG2
GenBank Nucleotide #
NM_001135021.1
NCBI Official Full Name
ELMO domain-containing protein 3
NCBI Official Synonym Full Names
ELMO domain containing 3
NCBI Official Symbol
ELMOD3
NCBI Official Synonym Symbols
LST3; RBED1; RBM29; DFNB88
UniProt Protein Name
ELMO domain-containing protein 3
UniProt Synonym Protein Names
RNA-binding motif and ELMO domain-containing protein 1; RNA-binding motif protein 29; RNA-binding protein 29
Protein Family
ELMO domain-containing protein
UniProt Gene Name
ELMOD3
UniProt Synonym Gene Names
RBED1; RBM29
NCBI Protein Information
ELMO domain-containing protein 3

NCBI Summary for ELMOD3

This gene encodes a member of the engulfment and cell motility family of GTPase-activating proteins that regulate Arf GTPase proteins. Members of this family are defined by a conserved engulfment and cell motility domain. In rat cochlea, the encoded protein is found in stereocilia, kinocilia and cuticular plate of developing hair cells suggesting a function for this protein in cochlear sensory cells. An allelic variant of this family has been associated with autosomal recessive nonsyndromic deafness-88 in humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
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UniProt Comments for ELMOD3

Acts as a GTPase-activating protein (GAP) for ARL2 with low specific activity.

Research Articles on ELMOD3

1. The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 resulted in loss of GAP activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with ELMOD3 recombinant protein

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >1 publications with ELMOD3 and Kidney Diseases

Organs/Tissues associated with ELMOD3 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with ELMOD3 and Kidney
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