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Mitotic Spindle Assembly Checkpoint Protein MAD2B (mad2l2) Xenopus Tropicalis Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1471423

MBS1471423 is a recombinant protein targeting mad2l2. Also known as Recombinant Xenopus tropicalis Mitotic spindle assembly checkpoint protein MAD2B (mad2l2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$865 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mitotic spindle assembly checkpoint protein MAD2B (mad2l2), Recombinant Protein
Full Product Name
Recombinant Xenopus tropicalis Mitotic spindle assembly checkpoint protein MAD2B (mad2l2)
Product Synonym Gene Name
mad2l2
Sequence
MTTLTRQDLN FGQVVADILC EFLEVAVHLI LYVREVYPIG IFQKRKKYNV PVQMSCHPEL NRYIQDTLHC VKPLIEKNDV EKVVVVILDK EHHPVERFVF EIAQPPLLSI SSDSLLSHVE QLLRAFILKI SVCDAVLDNN PPGCTFTLLV HTREAATRNM EKIQVIKDFP WILADEQDVH MQEPRLIPLK TMTSDILKMQ LYVEERAQKS T
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
24,401 Da
Sequence Positions
1-211, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q28H85
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of mad2l2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for mad2l2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mitotic spindle assembly checkpoint protein MAD2B isoform 1
NCBI Official Synonym Full Names
mitotic arrest deficient 2 like 2
NCBI Official Symbol
mad2l2
NCBI Official Synonym Symbols
mad2b
UniProt Protein Name
Mitotic spindle assembly checkpoint protein MAD2B
UniProt Synonym Protein Names
Mitotic arrest deficient 2-like protein 2; MAD2-like protein 2
UniProt Gene Name
mad2l2
UniProt Synonym Gene Names
MAD2-like protein 2
NCBI Protein Information
mitotic spindle assembly checkpoint protein MAD2B

UniProt Comments for mad2l2

Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Through transcriptional regulation may play a role in epithelial-mesenchymal transdifferentiation ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with mad2l2 recombinant protein

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