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GMP Reductase 2 (GMPR2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1471841

Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role… More details

$575 / 0.02 mg (Baculovirus) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GMP reductase 2 (GMPR2), Recombinant Protein
Full Product Name
Recombinant Human GMP reductase 2
Product Gene Name
Product Synonym Names
Guanosine 5'-monophosphate oxidoreductase 2; Guanosine monophosphate reductase 2
Sequence
MTSCLPALRF IATPRLSAMP HIDNDVKLDF KDVLLRPKRS TLKSRSEVDL TRSFSFRNSK QTYSGVPIIA ANMDTVGTFE MAKVLCKFSL FTAVHKHYSL VQWQEFAGQN PDCLEHLAAS SGTGSSDFEQ LEQILEAIPQ VKYICLDVAN GYSEHFVEFV KDVRKRFPQH TIMAGNVVTG EMVEELILSG ADIIKVGIGP GSVCTTRKKT GVGYPQLSAV MECADAAHGL KGHIISDGGC SCPGDVAKAF GAGADFVMLG GMLAGHSESG GELIERDGKK YKLFYGMSSE MAMKKYAGGV AEYRASEGKT VEVPFKGDVE HTIRDILGGI RSTCTYVGAA KLKELSRRTT FIRVTQQVNP IFSEAC
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Molecular Weight
55.8 kDa
Sequence Positions
1-366aa; Full Length of Isoform 2
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
610781
3D Structure
ModBase 3D Structure for Q9P2T1
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for GMPR2 recombinant protein

NADPH-dependent GMP reductase isoenzyme of human (GMPR2)

Other Notes

Small volumes of GMPR2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GMPR2 purchase

MBS1471841 is a recombinant protein targeting GMPR2. Also known as Recombinant Human GMP reductase 2. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for GMPR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GMP reductase 2 isoform 2
NCBI Official Synonym Full Names
guanosine monophosphate reductase 2
NCBI Official Symbol
GMPR2
NCBI Official Synonym Symbols
GMPR 2
UniProt Protein Name
GMP reductase 2
UniProt Synonym Protein Names
Guanosine 5'-monophosphate oxidoreductase 2
Protein Family
UniProt Gene Name
GMPR2
UniProt Synonym Gene Names
GMPR 2; Guanosine monophosphate reductase 2
UniProt Entry Name
GMPR2_HUMAN
NCBI Protein Information
GMP reductase 2

UniProt Comments for GMPR2

GMPR2: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation. Belongs to the IMPDH/GMPR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleotide Metabolism - purine; EC 1.7.1.7; Oxidoreductase

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: cytosol

Molecular Function: GMP reductase activity; metal ion binding

Biological Process: GMP metabolic process; nucleobase, nucleoside and nucleotide metabolic process; purine base metabolic process; purine salvage
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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