Human EDA2R Recombinant Protein – Cat# MBS147188

Ectodysplasin A2 Receptor (EDA2R) Human Recombinant Protein

Name: EDA2R Recombinant Protein; Ectodysplasin A2 Receptor; Human; MyBioSource
Brand: MyBioSource
SKU: MBS147188
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS147188

Description: EDA2R Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 380 amino acids (1-138a.a.) and having a molecular mass of 42.5kDa (Molecular size on SDS-PAGE will appear at approximately… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ectodysplasin A2 Receptor (EDA2R), Recombinant Protein

Full Product Name

Recombinant Human Ectodysplasin A2 Receptor, Sf9

Product Gene Name

EDA2R recombinant protein

Product Synonym Names

Tumor necrosis factor receptor superfamily member 27; X-linked ectodysplasin-A2 receptor; EDA-A2 receptor; Ectodysplasin A2 Receptor; X-Linked Ectodysplasin-A2 Receptor; EDA-A2 Receptor; TNFRSF27; XEDAR; Tumor Necrosis Factor Receptor Superfamily Member XEDAR; Tumor Necrosis Factor Receptor Superfamily Member 27; Ectodysplasin A2 Isoform Receptor; EDA-A2R; EDAA2R; EDA2R Human, Sf9; Ectodysplasin A2 Receptor Human Recombinant, Sf9

Sequence

ADP MDCQENE YWDQWGRCVT CQRCGPGQEL SKDCGYGEGG DAYCTACPPR RYKSSWGHHR CQSCITCAVI NRVQKVNCTA TSNAVCGDCL PRFYRKTRIG GLQDQECIPC TKQTPTSEVQ CAFQLSLVEA DAPTVPPQEA TLEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SRDELTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGKHHHHHH .

Host

Sf9, Baculovirus cells

Form/Format

Sterile filtered clear solution
Protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4), 20% glycerol and 1mM DTT

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles

Molecular Weight

32,959 Da

OMIM

AF298812 mRNA

3D Structure

ModBase 3D Structure for Q9HAV5

Product Categories/Family for EDA2R recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Ectodysplasin; EDA2R Human; Sf9

Other Notes

Small volumes of EDA2R recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EDA2R purchase

MBS147188 is a recombinant protein targeting EDA2R. Also known as Recombinant Human Ectodysplasin A2 Receptor, Sf9. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for EDA2R. It may not necessarily be applicable to this product.

NCBI GI #

313104030

NCBI GeneID

60401

NCBI Accession #

Q9HAV5.2

UniProt Primary Accession #

Q9HAV5

UniProt Secondary Accession #

Q5VYX9; Q5VYY0; Q6UWM2; Q8IZA6

UniProt Related Accession #

Q9HAV5

NCBI Official Full Name

Tumor necrosis factor receptor superfamily member 27

NCBI Official Synonym Full Names

ectodysplasin A2 receptor

NCBI Official Symbol

EDA2R

NCBI Official Synonym Symbols

XEDAR; EDAA2R; EDA-A2R; TNFRSF27

UniProt Protein Name

Tumor necrosis factor receptor superfamily member 27

UniProt Synonym Protein Names

X-linked ectodysplasin-A2 receptor; EDA-A2 receptor

Protein Family

Tumor necrosis factor receptor superfamily

UniProt Gene Name

EDA2R

UniProt Synonym Gene Names

TNFRSF27; XEDAR; EDA-A2 receptor

NCBI Protein Information

tumor necrosis factor receptor superfamily member 27

NCBI Summary for EDA2R

The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016]

UniProt Comments for EDA2R

Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.

Research Articles on EDA2R

1. We found evidence for AR but not EDA2R as the candidate gene at the androgenetic alopecia risk locus on chromosome X.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with EDA2R recombinant protein

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
TNFR2 Non-canonical NF-kB Pathway antibodies	TNFR2 Non-canonical NF-kB Pathway Diagram
TNFs Bind Their Physiological Receptors Pathway antibodies	TNFs Bind Their Physiological Receptors Pathway Diagram

Diseases associated with EDA2R recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>11 publications with EDA2R and Necrosis
Congenital Abnormalities Antibodies	>2 publications with EDA2R and Congenital Abnormalities
Inflammation Antibodies	>2 publications with EDA2R and Inflammation
Breast Neoplasms Antibodies	>2 publications with EDA2R and Breast Neoplasms
Carcinoma Antibodies	>1 publications with EDA2R and Carcinoma
Ovarian Neoplasms Antibodies	>1 publications with EDA2R and Ovarian Neoplasms
Neoplasms, Experimental Antibodies	>1 publications with EDA2R and Neoplasms, Experimental
Lung Neoplasms Antibodies	>1 publications with EDA2R and Lung Neoplasms

Organs/Tissues associated with EDA2R recombinant protein

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>7 publications with EDA2R and Skin
Brain Antibodies	>3 publications with EDA2R and Brain
Bone Antibodies	>2 publications with EDA2R and Bone
Muscle Antibodies	>1 publications with EDA2R and Muscle
Lung Antibodies	>1 publications with EDA2R and Lung
Embryonic Tissue Antibodies	>1 publications with EDA2R and Embryonic Tissue