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C Receptor (PROCR) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS147227

Description: PROCR Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 435 amino acids (18-210a.a.) and having a molecular mass of 49.3kDa (Molecular size on SDS-PAGE will appear at approximately… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
c Receptor (PROCR), Recombinant Protein
Full Product Name
Recombinant Human Protein-c Receptor, Sf9
Product Gene Name
PROCR recombinant protein
Product Synonym Names
Proteasomal ubiquitin receptor ADRM1; 110 kDa cell membrane glycoprotein; Gp110; Adhesion-regulating molecule 1; ARM-1; Proteasome regulatory particle non-ATPase 13; hRpn13; Rpn13 homolog; ADRM1; ARM1; Rpn13; PROCR Human, Sf9; Protein-c Receptor Human Recombinant, Sf9
Sequence
ADP SQDASDG LQRLHMLQIS YFRDPYHVWY QGNASLGGHL THVLEGPDTN TTIIQLQPLQ EPESWARTQS GLQSYLLQFH GLVRLVHQER TLAFPLTIRC FLGCELPPEG SRAHVFFEVA VNGSSFVSFR PERALWQADT QVTSGVVTFT LQQLNAYNRT RYELREFLED TCVQYVQKHI SAENTKGSQT SRSYTSLEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH.
Host
Sf9, Baculovirus cells
Form/Format
Sterile filtered colorless solution
Protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
Molecular Weight
26,671 Da
OMIM
L35545 mRNA
3D Structure
ModBase 3D Structure for Q9UNN8

Product Categories/Family for PROCR recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Other; PROCR Human; Sf9

Other Notes

Small volumes of PROCR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PROCR purchase

MBS147227 is a recombinant protein targeting PROCR. Also known as Recombinant Human Protein-c Receptor, Sf9. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for PROCR. It may not necessarily be applicable to this product.

NCBI GI #
13626550
NCBI GeneID
10544
NCBI Accession #
Q9UNN8.1
UniProt Primary Accession #
Q9UNN8
UniProt Secondary Accession #
Q14218; Q6IB56; Q96CB3; Q9ULX1; B2RC04
UniProt Related Accession #
Q9UNN8
NCBI Official Full Name
Endothelial protein C receptor
NCBI Official Synonym Full Names
protein C receptor
NCBI Official Symbol
PROCR
NCBI Official Synonym Symbols
CCCA; EPCR; CCD41
UniProt Protein Name
Endothelial protein C receptor
UniProt Synonym Protein Names
Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD_antigen: CD201
Protein Family
Endothelial protein C receptor
UniProt Gene Name
PROCR
UniProt Synonym Gene Names
EPCR; APC receptor
NCBI Protein Information
endothelial protein C receptor

NCBI Summary for PROCR

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]
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UniProt Comments for PROCR

Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.

Research Articles on PROCR

1. analysis of renal endothelial PROCR expression and shedding during diabetic nephropathy

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PROCR recombinant protein

 Reference Product  PubMed Publications
 APC recombinant protein  >74 publications with PROCR and APC
 THBD recombinant protein  >8 publications with PROCR and THBD
 PROC recombinant protein  >6 publications with PROCR and PROC
 CCL2 recombinant protein  >3 publications with PROCR and CCL2
 CAV1 recombinant protein  >3 publications with PROCR and CAV1
 F2R recombinant protein  >2 publications with PROCR and F2R
 F2RL1 recombinant protein  >1 publications with PROCR and F2RL1

Diseases associated with PROCR recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >79 publications with PROCR and Inflammation
 Cardiovascular Diseases Antibodies  >66 publications with PROCR and Cardiovascular Diseases
 Necrosis Antibodies  >31 publications with PROCR and Necrosis
 Nervous System Diseases Antibodies  >21 publications with PROCR and Nervous System Diseases
 Disease Models, Animal Antibodies  >13 publications with PROCR and Disease Models, Animal
 Heart Diseases Antibodies  >12 publications with PROCR and Heart Diseases
 Breast Neoplasms Antibodies  >9 publications with PROCR and Breast Neoplasms
 Kidney Diseases Antibodies  >8 publications with PROCR and Kidney Diseases
 Hemorrhage Antibodies  >7 publications with PROCR and Hemorrhage
 Lung Neoplasms Antibodies  >5 publications with PROCR and Lung Neoplasms

Organs/Tissues associated with PROCR recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >155 publications with PROCR and Blood
 Vascular Antibodies  >111 publications with PROCR and Vascular
 Lung Antibodies  >21 publications with PROCR and Lung
 Brain Antibodies  >13 publications with PROCR and Brain
 Bone Antibodies  >12 publications with PROCR and Bone
 Heart Antibodies  >11 publications with PROCR and Heart
 Kidney Antibodies  >10 publications with PROCR and Kidney
 Embryonic Tissue Antibodies  >9 publications with PROCR and Embryonic Tissue
 Muscle Antibodies  >9 publications with PROCR and Muscle
 Umbilical Cord Antibodies  >9 publications with PROCR and Umbilical Cord
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