Human BTN3A1 Recombinant Protein – Cat# MBS147243

Butyrophilin Subfamily 3 Member A1 (BTN3A1) Human Recombinant Protein

Name: BTN3A1 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS147243
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS147243

Description: BTN3A1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 464 amino acids (30-254a.a.) and having a molecular mass of 51.1kDa (Molecular size on SDS-PAGE will appear at approximately… More details

$250 / 0.001 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Butyrophilin Subfamily 3 Member A1 (BTN3A1), Recombinant Protein

Full Product Name

Recombinant Human Butyrophilin Subfamily 3 Member A1

Product Gene Name

BTN3A1 recombinant protein

Product Synonym Names

Butyrophilin Subfamily 3 Member A1; BTF5; DJ45P21.3 (Butyrophilin; Subfamily 3; Member A1); Butyrophilin; Subfamily 3; Member A1; CD277 Antigen; BTN3.1; BT3.1; CD277; Butyrophilin subfamily 3 member A1; BTN3A1 Human; Butyrophilin Subfamily 3 Member A1 Human Recombinant

Sequence

QFSVLGPSGP ILAMVGEDAD LPCHLFPTMS AETMELKWVS SSLRQVVNVY ADGKEVEDRQ SAPYRGRTSI LRDGITAGKA ALRIHNVTAS DSGKYLCYFQ DGDFYEKALV ELKVAALGSD LHVDVKGYKD GGIHLECRST GWYPQPQIQW SNNKGENIPT VEAPVVADGV GLYAVAASVI MRGSSGEGVS CTIRSSLLGL EKTASISIAD PFFRSAQRWI AALAGLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH.

Host

Sf9, Baculovirus cells

Form/Format

Sterile filtered colorless solution
Protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles

Molecular Weight

52,019 Da

OMIM

Y07827 mRNA

3D Structure

ModBase 3D Structure for O00481

Product Categories/Family for BTN3A1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Other; BTN3A1 Human

Other Notes

Small volumes of BTN3A1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BTN3A1 purchase

MBS147243 is a recombinant protein targeting BTN3A1. Also known as Recombinant Human Butyrophilin Subfamily 3 Member A1. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for BTN3A1. It may not necessarily be applicable to this product.

NCBI GI #

117949374

NCBI GeneID

11119

NCBI Accession #

O00481.3

UniProt Primary Accession #

O00481

UniProt Secondary Accession #

Q0P515; Q147X5; Q53F15; Q99420; Q9HCY1; A2A278; A8K2C8; B4DIQ1; B4DRM2; E9PGB4; E9PHG8

UniProt Related Accession #

O00481

NCBI Official Full Name

Butyrophilin subfamily 3 member A1

NCBI Official Synonym Full Names

butyrophilin subfamily 3 member A1

NCBI Official Symbol

BTN3A1

NCBI Official Synonym Symbols

BTF5; BT3.1; CD277; BTN3.1

UniProt Protein Name

Butyrophilin subfamily 3 member A1

UniProt Synonym Protein Names

CD_antigen: CD277

Protein Family

Butyrophilin subfamily

UniProt Gene Name

BTN3A1

UniProt Synonym Gene Names

BTF5

NCBI Protein Information

butyrophilin subfamily 3 member A1

NCBI Summary for BTN3A1

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

UniProt Comments for BTN3A1

Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

Research Articles on BTN3A1

1. results show that ligand binding to BTN3A1 induces a conformational change within the intracellular domain that involves the JM region and is required for full activation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with BTN3A1 recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>2 publications with BTN3A1 and Necrosis
Inflammation Antibodies	>1 publications with BTN3A1 and Inflammation

Organs/Tissues associated with BTN3A1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>18 publications with BTN3A1 and Blood
Brain Antibodies	>2 publications with BTN3A1 and Brain
Mammary Gland Antibodies	>1 publications with BTN3A1 and Mammary Gland