Human RAET1E Recombinant Protein – Cat# MBS147256

Retinoic Acid Early Transcript 1e (RAET1E) Human Recombinant Protein

Name: RAET1E Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS147256
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS147256

Description: RAET1E Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 204 amino acids (31-225 a.a.) and having a molecular mass of 23.4kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).… More details

$250 / 0.001 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Retinoic Acid Early Transcript 1E (RAET1E), Recombinant Protein

Full Product Name

Recombinant Human Retinoic Acid Early Transcript 1E, Sf9

Product Gene Name

RAET1E recombinant protein

Product Synonym Names

Retinoic Acid Early Transcript 1E; Lymphocyte Effector Toxicity Activation Ligand; RAE-1-Like Transcript 4; NKG2DL4; N2DL-4; LETAL; ULBP4; RL-4; NKG2D Ligand 4; BA350J20.7; RAET1E2; N2DL4; RAET1E Human, Sf9; Retinoic Acid Early Transcript 1E Human Recombinant, Sf9

Sequence

ADP HSLCFNF TIKSLSRPGQ PWCEAQVFLN KNLFLQYNSD NNMVKPLGLL GKKVYATSTW GELTQTLGEV GRDLRMLLCD IKPQIKTSDP STLQVEMFCQ REAERCTGAS WQFATNGEKS LLFDAMNMTW TVINHEASKI KETWKKDRGL EKYFRKLSKG DCDHWLREFL GHWEAMPEPT VSPVNASDIH WSSSSLPDHH HHHH.

Host

Sf9, Baculovirus cells

Form/Format

Sterile filtered colorless solution
Protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles

Molecular Weight

32,300 Da

OMIM

AY069961 mRNA

3D Structure

ModBase 3D Structure for Q8TD07

Product Categories/Family for RAET1E recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Retinoic Acid Early Transcript; RAET1E Human; Sf9

Other Notes

Small volumes of RAET1E recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAET1E purchase

MBS147256 is a recombinant protein targeting RAET1E. Also known as Recombinant Human Retinoic Acid Early Transcript 1E, Sf9. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for RAET1E. It may not necessarily be applicable to this product.

NCBI GI #

47605907

NCBI GeneID

135250

NCBI Accession #

Q8TD07.1

UniProt Primary Accession #

Q8TD07

UniProt Secondary Accession #

Q5VYB7; Q5VYB8; Q8TEZ2; Q96L41; A6YF59

UniProt Related Accession #

Q8TD07

NCBI Official Full Name

Retinoic acid early transcript 1E

NCBI Official Synonym Full Names

retinoic acid early transcript 1E

NCBI Official Symbol

RAET1E

NCBI Official Synonym Symbols

RL-4; LETAL; ULBP4; N2DL-4; NKG2DL4; RAET1E2; bA350J20.7

UniProt Protein Name

Retinoic acid early transcript 1E

UniProt Synonym Protein Names

Lymphocyte effector toxicity activation ligand

Protein Family

NKG2D ligand

UniProt Gene Name

RAET1E

UniProt Synonym Gene Names

N2DL-4; NKG2DL4

NCBI Protein Information

retinoic acid early transcript 1E; NKG2D ligand 4

NCBI Summary for RAET1E

This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]

UniProt Comments for RAET1E

Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.

Research Articles on RAET1E

1. Blocking the interaction of NKG2D with its ligands deleted the sensitizing effects of HCQ. In addition, we showed that HCQ did not affect the synthesis or degradation of ULBP4, but induced the translocation of ULBP4 from the cytoplasm to the cell membrane

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with RAET1E recombinant protein

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies	Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
Natural Killer Cell Mediated Cytotoxicity Pathway antibodies	Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
Natural Killer Cell Mediated Cytotoxicity Pathway antibodies	Natural Killer Cell Mediated Cytotoxicity Pathway Diagram

Diseases associated with RAET1E recombinant protein

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>3 publications with RAET1E and Disease Models, Animal
Atherosclerosis Antibodies	>2 publications with RAET1E and Atherosclerosis
Cardiovascular Diseases Antibodies	>2 publications with RAET1E and Cardiovascular Diseases
Arteriosclerosis Antibodies	>2 publications with RAET1E and Arteriosclerosis
Carcinoma, Hepatocellular Antibodies	>1 publications with RAET1E and Carcinoma, Hepatocellular
Nervous System Diseases Antibodies	>1 publications with RAET1E and Nervous System Diseases
Liver Diseases Antibodies	>1 publications with RAET1E and Liver Diseases
Liver Neoplasms Antibodies	>1 publications with RAET1E and Liver Neoplasms
Inflammation Antibodies	>1 publications with RAET1E and Inflammation
Necrosis Antibodies	>1 publications with RAET1E and Necrosis

Organs/Tissues associated with RAET1E recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>2 publications with RAET1E and Liver
Brain Antibodies	>1 publications with RAET1E and Brain
Skin Antibodies	>1 publications with RAET1E and Skin
Cervix Antibodies	>1 publications with RAET1E and Cervix